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Glioblastoma Clinical Trials

Browse 285 glioblastoma clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

for
Glioma, IDH Mutation, Astrocytoma, Oligodendroglioma
Location: Philadelphia PA
Sponsor: Stephen Bagley, MD, MSCE

Sex: All

Age: 18+

Code: NCT05345002

Phase2, Recruiting
Active & Responsive

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

for
Central Nervous System Tumor, Diffuse Intrinsic Pontine Glioma,
Location: Seattle WA
Sponsor: Seattle Children's Hospital

Sex: All

Age: 1 - 26

Code: NCT04185038

Phase1, Recruiting
Active & Responsive

A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy

for
Phase 1b, Open Label, REC-617, RB1-Negative, Leiomyosarcoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07633756

Phase1, Recruiting
Active & Responsive

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: New York NY, Orange CA
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07486713

Recruiting
Active & Responsive

Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

for
Glioma, Malignant
Location: Durham NC
Sponsor: Darell Bigner

Sex: All

Age: 18+

Code: NCT04547777

Phase1, Recruiting

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Active & Responsive

FUS Etoposide for DMG

for
Diffuse Intrinsic Pontine Glioma,
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 4 - 21

Code: NCT05762419

Phase1, Recruiting
New

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: The Bronx NY, New York NY, Bel Air MD, Glen Burnie MD,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07452458

Phase3, Recruiting
New

A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma

for
Phase 1, NK Cell, IL13Ra, EGFRvIII,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07579208

Phase1, Recruiting
New

Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma

for
Glioblastoma, IDH-Wildtype
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07708961

Phase2, Recruiting

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue

for
Glioblastoma, Glioblastoma Multiforme, Gliosarcoma
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT05756985

Recruiting

Combining Sunitinib, Temozolomide and Radiation to Treat Patients Diagnosed With Glioblastoma

for
Glioblastoma Multiforme
Location: Montreal, Calgary
Sponsor: Bassam Abdulkarim

Sex: All

Age: 18 - 70

Code: NCT02928575

Phase2, Recruiting

A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma

for
Glioblastoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06672575

Phase1, Phase2, Recruiting

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

for
High Grade Glioma, Glioblastoma
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05565118

Phase1, Recruiting

A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

for
Glioblastoma Multiforme
Location: Durham NC, Los Angeles CA, Santa Monica CA,
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT05708352

Phase2, Recruiting

Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions

for
Glioma, Glioblastoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04047264

Recruiting

FDG and FDOPA PET Demonstration of Functional Brain Abnormalities

for
Glioblastoma
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT04315584

Early_phase1, Recruiting

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

for
Glioblastoma
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06625684

Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for
Diffuse Astrocytoma, IDH-Mutant, Glioblastoma, IDH-wildtype,
Location: Boston MA, Boynton Beach FL, Nashville TN, Dallas TX,
Sponsor: Neonc Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06047379

Phase1, Phase2, Recruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

for
Glioma, Glioma, Malignant, Glioblastoma,
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT05979064

Recruiting

Lerapolturev (PVSRIPO) in GBM

for
Recurrent Supratentorial Glioblastoma
Location: Durham NC
Sponsor: Darell Bigner

Sex: All

Age: 18+

Code: NCT06177964

Phase2, Recruiting