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Leukemia Clinical Trials

Browse 1,316 Leukemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study

for
Chronic Graft-versus-Host-Disease, Leukemia,
Location: New York NY, Montreal, Buffalo NY, Charlotte NC,
Sponsor: University of British Columbia

Sex: All

Age: 0 - 24

Code: NCT04372524

Recruiting

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

for
B-cell Acute Lymphoblastic Leukemia,
Location: Boston MA, Buffalo NY, Chicago IL
Sponsor: Marlise Luskin, MD

Sex: All

Age: 18+

Code: NCT03595917

Phase1, Recruiting

Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: Boston MA, New Haven CT, Hackensack NJ, Montreal,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06419634

Phase1, Recruiting

Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT03986034

Phase2, Recruiting

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

for
Acute Lymphoblastic Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT03128034

Phase1, Phase2, Recruiting

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AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia

for
B-cell Acute Lymphoblastic Leukemia (B-ALL)
Location: New York NY, Richmond VA, Tampa FL, Atlanta GA,
Sponsor: AstraZeneca

Sex: All

Age: 12+

Code: NCT06137118

Phase1, Phase2, Recruiting

Long-term Follow-up Study of Patients Receiving CAR-T Cells

for
Chronic Lymphocytic Leukemia, Lymphomas Non-Hodgkin's B-Cell,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18 - 70+

Code: NCT03375619

Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

for
Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL,
Location: Boston MA, Providence RI, The Bronx NY, New York NY,
Sponsor: Schrödinger, Inc.

Sex: All

Age: 18+

Code: NCT05544019

Phase1, Recruiting

Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL

for
Relapsed or Refractory CD19+ B-cell Lymphoma,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05963217

Phase1, Recruiting

Identify Barriers to Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed and Relapsed Acute Leukemia

for
Acute Leukemia, Newly Diagnosed, Relapsed
Location: Hartford CT, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT02677064

Recruiting

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for
Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma,
Location: Boston MA, Providence RI, New York NY, Hackensack NJ,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06564038

Phase1, Phase2, Recruiting

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

for
B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma,
Location: Valhalla NY, Chapel Hill NC, Jacksonville FL,
Sponsor: Vironexis Biotherapeutics Inc.

Sex: All

Age: 13 - 70+

Code: NCT06533579

Phase1, Phase2, Recruiting

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

for
Myeloid Leukemia, Philadelphia Positive
Location: Boston MA, New York NY, Philadelphia PA, Cincinnati OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 1 - 17

Code: NCT04925479

Phase1, Phase2, Recruiting

CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT06777979

Phase1, Recruiting

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for
Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer,
Location: Miami FL, Florence SC, Charleston SC, Cleveland OH,
Sponsor: Adela, Inc

Sex: All

Age: 40+

Code: NCT05366881

Recruiting

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

for
Acute Biphenotypic Leukemia, Acute Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 65

Code: NCT02115295

Phase2, Recruiting

Chart Review Study of Chronic Myelogenous Leukemia (CML) Patients Treated With Imatinib Outside of a Clinical Trial

for
Chronic Myelogenous Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT00816114

Recruiting

Fractionated Gemtuzumab Ozogamicin in Treating Measurable Residual Disease in Patients With Acute Myeloid Leukemia

for
Acute Myeloid Leukemia
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT03737955

Phase2, Recruiting

UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1

for
Acute Lymphoid Leukemia, Acute Lymphoblastic Leukemia
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18+

Code: NCT05535855

Phase1, Recruiting

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

for
Acute Leukemia of Ambiguous Lineage,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 0 - 65

Code: NCT06013423

Phase2, Recruiting

What are clinical trials for leukemia?

Clinical trials for leukemia are research studies designed to evaluate new treatments, therapies, or diagnostic methods for different types of leukemia, a group of cancers that affect the blood and bone marrow. These trials aim to discover more effective ways to treat leukemia, manage its symptoms, and improve patient outcomes. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.

Why are leukemia clinical trials important?

Leukemia clinical trials are crucial because they drive advancements in treatment by testing new therapies, improving existing ones, and exploring novel approaches to manage and potentially cure the disease. These trials provide essential data on the safety and effectiveness of new treatments, which can lead to better outcomes and fewer side effects compared to current options.

Types of clinical trials for leukemia

Why participate in a leukemia clinical trial

Who can participate in a clinical trial for leukemia?

How to enroll in a leukemia clinical trial