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Leukemia Clinical Trials

Browse 1,316 Leukemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML

for
Acute Myeloid Leukemia With FLT3/ITD Mutation
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05024552

Phase1, Recruiting

Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control Subjects

for
Chronic Lymphocytic Leukemia, Monoclonal B-Cell Lymphocytosis
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 40+

Code: NCT06536452

Recruiting

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

for
Neurofibroma, Plexiform,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 3 - 35

Code: NCT02390752

Phase1, Recruiting

Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

for
Chronic Lymphocytic Leukaemia,
Location: Philadelphia PA, Columbus OH
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06651970

Recruiting

Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML

for
Acute Monocytic Leukemia, Acute Myeloid Leukemia
Location: Miami FL, Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06504459

Phase2, Recruiting

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A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Norwich CT, Hackensack NJ, Albany NY, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06136559

Phase3, Recruiting

CAR T-cell Therapy in Patients With Renal Dysfunction

for
Non-hodgkin Lymphoma,B Cell, Multiple Myeloma,
Location: Atlanta GA
Sponsor: Northside Hospital, Inc.

Sex: All

Age: 18+

Code: NCT05909059

Phase2, Recruiting

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

for
Hairy Cell Leukemia (HCL), Chronic Lymphocytic Leukemia (CLL),
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT01087333

Recruiting

Cord Blood Transplant in Adults With Blood Cancers

for
Acute Myelogenous Leukemia (AML),
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 21 - 65

Code: NCT05884333

Phase2, Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

for
Acute Leukemia, Acute Lymphoblastic Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 0+

Code: NCT04195633

Phase2, Recruiting

Myeloproliferative Neoplasms (MPNs) Patient Registry

for
Primary Myelofibrosis, Polycythemia Vera,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 0+

Code: NCT02760238

Recruiting

Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia
Location: Atlanta GA
Sponsor: Northside Hospital, Inc.

Sex: All

Age: 18+

Code: NCT05519579

Phase2, Recruiting

SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome,
Location: Boston MA, Houston TX, Duarte CA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT03113643

Phase1, Recruiting

Venetoclax to Augment Epigenetic Modification and Chemotherapy

for
Acute Myeloid Leukemia, in Relapse,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 1 - 25

Code: NCT05317403

Phase1, Recruiting

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for
Acute Myeloid Leukemia With Gene Mutations,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04493164

Phase2, Recruiting

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

for
Chronic Lymphocytic Leukemia (CLL),
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT05724121

Recruiting

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for
Acute Myeloid Leukemia, Mixed Lineage Leukemia Gene Mutation,
Location: Boston MA, Worcester MA, New Haven CT, Stony Brook NY,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT05735184

Phase1, Recruiting

Third-Party Natural Killer Cells and Mogamulizumab for the Treatment of Relapsed or Refractory Cutaneous T-cell Lymphomas or Adult T-Cell Leukemia/Lymphoma

for
Recurrent Adult T-Cell Leukemia/Lymphoma,
Location: Columbus OH
Sponsor: John Reneau

Sex: All

Age: 18+

Code: NCT04848064

Phase1, Recruiting

Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS

for
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: The Bronx NY
Sponsor: Montefiore Medical Center

Sex: All

Age: 18 - 70+

Code: NCT05342584

Phase1, Recruiting

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

for
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: Charlottesville VA, Rochester NY, Jacksonville FL,
Sponsor: Chordia Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05732103

Phase1, Phase2, Recruiting

What are clinical trials for leukemia?

Clinical trials for leukemia are research studies designed to evaluate new treatments, therapies, or diagnostic methods for different types of leukemia, a group of cancers that affect the blood and bone marrow. These trials aim to discover more effective ways to treat leukemia, manage its symptoms, and improve patient outcomes. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.

Why are leukemia clinical trials important?

Leukemia clinical trials are crucial because they drive advancements in treatment by testing new therapies, improving existing ones, and exploring novel approaches to manage and potentially cure the disease. These trials provide essential data on the safety and effectiveness of new treatments, which can lead to better outcomes and fewer side effects compared to current options.

Types of clinical trials for leukemia

Why participate in a leukemia clinical trial

Who can participate in a clinical trial for leukemia?

How to enroll in a leukemia clinical trial