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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

for
Hepatoblastoma, Hepatocellular Carcinoma (HCC), Liver Neoplasms,
Location: Boston MA, Orange CA, Los Angeles CA, San Francisco CA
Sponsor: Eureka Therapeutics Inc.

Sex: All

Age: 1 - 21

Code: NCT04634357

Phase1, Phase2, Recruiting

Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence: Study 3

for
Acute Lymphoblastic Leukemia, Pediatric
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 3 - 9

Code: NCT06074666

Recruiting

Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

for
Prostate Cancer
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: Male

Age: 40 - 70+

Code: NCT03769766

Phase3, Recruiting

ALG.APV-527 First-in-human Study

for
Solid Tumor
Location: Port Saint Lucie FL
Sponsor: Aptevo Therapeutics

Sex: All

Age: 18+

Code: NCT05934539

Phase1, Phase2, Recruiting

Study of Liposomal Annamycin in Patients With Refractory or Relapsed Acute Lymphocytic Leukemia

for
Acute Lymphocytic Leukemia
Location: Bronx NY, Buffalo NY, Houston TX
Sponsor: Callisto Pharmaceuticals

Sex: All

Age: 15+

Code: NCT00271063

Phase1, Phase2, Recruiting

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Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

for
Melanoma, NSCLC, Hepatocellular Carcinoma, Urothelial Cancer,
Location: Pittsburgh PA
Sponsor: Dan Zandberg

Sex: All

Age: 18+

Code: NCT04114136

Phase2, Recruiting

Evaluation of Stool Tagging for Improved Patient Compliance

for
Colon Cancer, Polyps
Location: Chesterfield MO
Sponsor: Center for Diagnostic Imaging

Sex: All

Age: 45 - 70+

Code: NCT00124163

Recruiting

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

for
Prostate Cancer, Malignant Neoplasm of Prostate,
Location: New York NY, Cleveland OH, Madison WI
Sponsor: Case Comprehensive Cancer Center

Sex: Male

Age: 18+

Code: NCT06150417

Phase2, Recruiting

A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

for
Relapsed/Refractory Follicular Lymphoma,
Location: Lebanon NH, Stony Brook NY, Plantation FL,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06149286

Phase3, Recruiting

Autologous CAR-T Cells Targeting B7-H3 in PDAC

for
Pancreas Cancer, Relapse, Resistant Cancer
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06158139

Phase1, Recruiting

A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas

for
Relapsed/Refractory Non-Hodgkin Lymphoma
Location: Boston MA, New York NY, Tampa FL, Rochester MN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06090539

Phase1, Phase2, Recruiting

Registry for Esophageal and Gastroesophageal Junction Cancer

for
Gastroesophageal-junction Cancer, Esophageal Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06558786

Recruiting

A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors

for
Advanced Cancer, Solid Tumor, Metastatic Cancer
Location: Miami FL, Omaha NE, Duarte CA
Sponsor: Proviva Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06190886

Phase1, Recruiting

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

for
Small Cell Lung Cancer (SCLC),
Location: Boston MA, New Haven CT, Baltimore MD, Fairfax VA,
Sponsor: Phanes Therapeutics

Sex: All

Age: 18+

Code: NCT05652686

Phase1, Phase2, Recruiting

Assessment of Cardiotoxicity by Cardiac Magnetic Resonance (CMR) in Breast Cancer Patients Receiving Trastuzumab

for
Stage I-IV Breast Cancer (Neo-adjuvant, Adjuvant, Locally Advanced and Metastatic),
Location: Toronto
Sponsor: Unity Health Toronto

Sex: All

Age: 18+

Code: NCT01022086

Recruiting

HIFU for Focal Ablation of Prostate Tissue: An Observational Study

for
Prostate Cancer
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: Male

Age: 40 - 70+

Code: NCT03620786

Recruiting

Loncastuximab Tesirine and Rituximab Followed by DA-EPOCH-R for Treating Patients With High-Risk Diffuse Large B-cell Lymphoma

for
Double-Expressor Lymphoma,
Location: San Diego CA, Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT05600686

Phase2, Recruiting

Clinical Trial of PM54 in Advanced Solid Tumors Patients.

for
Advanced Solid Tumor
Location: San Antonio TX
Sponsor: PharmaMar

Sex: All

Age: 18+

Code: NCT05841563

Phase1, Recruiting

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

for
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18 - 70+

Code: NCT01890486

Recruiting

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Ductal Adenocarcinoma,
Location: Lake Success NY, Miami FL, Detroit MI, Houston TX,
Sponsor: PanTher Therapeutics

Sex: All

Age: 18+

Code: NCT06673017

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer