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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

for
Advanced Lung Neuroendocrine Tumor,
Location: Boston MA, Philadelphia PA, Deerfield Beach FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04665739

Phase2, Recruiting

Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer

for
Pancreatic Cancer Metastatic
Location: Brooklyn NY
Sponsor: State University of New York - Downstate Medical Center

Sex: All

Age: 18+

Code: NCT06030622

Phase1, Phase2, Recruiting

Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial

for
Prostate Adenocarcinoma
Location: Durham NC, Chicago IL, Madison WI, Los Angeles CA
Sponsor: National Cancer Institute (NCI)

Sex: Male

Age: 18+

Code: NCT06022822

Phase2, Recruiting

Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma

for
Breast Cancer, Lymphoma, Hodgkin's Lymphoma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT01788839

Recruiting

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for
Multiple Myeloma
Location: Providence RI, Farmington CT, New Haven CT, Lebanon NH,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05552222

Phase3, Recruiting

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Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

for
Ovarian Neoplasms, Ovarian Epithelial Carcinoma,
Location: Boston MA, Annapolis MD, Baltimore MD, Little Rock AR,
Sponsor: Massachusetts General Hospital

Sex: Female

Age: 30+

Code: NCT04794322

Recruiting

Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

for
Bladder Cancer
Location: Baltimore MD, Washington D.C. DC
Sponsor: Johns Hopkins University

Sex: Male

Age: 18+

Code: NCT05792722

Recruiting

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for
Superficial Bladder Cancer,
Location: Halifax, Boston MA, New Haven NY, Albany NY,
Sponsor: enGene, Inc.

Sex: All

Age: 18+

Code: NCT04752722

Phase1, Phase2, Recruiting

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

for
Gastric Adenocarcinoma, Oligometastasis,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT03161522

Phase2, Recruiting

Breath Test for Biomarkers in Humans Receiving Total Body Irradiation

for
Radiation Injury
Location: New York NY, Hackensack NJ, Atlanta GA
Sponsor: Menssana Research, Inc.

Sex: All

Age: 18+

Code: NCT02152722

Recruiting

Acutherapy to Prevent Aromatase Inhibitor-Associated Arthralgias in Non-Hispanic Black Postmenopausal Women With Early-Stage Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: Female

Age: 18+

Code: NCT06534125

Recruiting

Study of STP938 (Dencatistat) in Advanced Solid Tumours

for
Solid Tumor
Location: St. Petersburg FL, Dallas TX, San Antonio TX
Sponsor: Step Pharma, SAS

Sex: All

Age: 18+

Code: NCT06297525

Phase1, Recruiting

Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer

for
Pancreatic Cancer Non-resectable, Pancreatic Cancer Metastatic,
Location: Saint Louis Park MN
Sponsor: HealthPartners Institute

Sex: All

Age: 18+

Code: NCT06605430

Phase2, Recruiting

Galleri® in the Medicare Population.

for
Cancer
Location: Bloomsburg PA, Morgantown WV, Buckhannon WV, Tampa FL,
Sponsor: GRAIL, Inc.

Sex: All

Age: 50+

Code: NCT05673018

Recruiting

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for
High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer,
Location: Boston MA, Burlington MA, Hartford CT, Springfield MA,
Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female

Age: 18+

Code: NCT05128825

Phase2, Recruiting

Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes

for
Metastatic Castration-resistant Prostate Cancer,
Location: Quebec, Montreal, Ottawa, Toronto, Brampton, Kitchener,
Sponsor: Canadian Cancer Trials Group

Sex: Male

Age: 18+

Code: NCT06439225

Phase3, Recruiting

Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response

for
Pancreatic Cancer
Location: Columbus OH, Nashville TN
Sponsor: Ohio State University

Sex: All

Age: 19+

Code: NCT04588025

Recruiting

Zanubrutinib and Venetoclax in CLL (ZANU-VEN)

for
Chronic Lymphocytic Leukemia (CLL),
Location: Scarborough ME, South Weymouth MA, Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT05168930

Phase2, Recruiting

Castrate Resistant Prostate Cancer Enhertu Therapy

for
Prostate Cancer Metastatic, Prostate Cancer, CRPC
Location: Washington D.C. DC
Sponsor: Washington D.C. Veterans Affairs Medical Center

Sex: Male

Age: 18+

Code: NCT06610825

Phase2, Recruiting

Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

for
Castration-Resistant Prostate Carcinoma,
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Male

Age: 18+

Code: NCT05168618

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer