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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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1

Adaptive Versus Non-adaptive Radiotherapy and 2 Bladder Filling Instructions for Patients With Intermediate or High Risk Localized Prostate Cancer (ARP)

for
Prostate Cancer
Location: Vancouver
Sponsor: Scott Tyldesley

Sex: Male

Age: 18+

Code: NCT06678126

Phase 2, Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for
Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung
Location: Philadelphia PA, Fairfax VA, Dallas TX,
Sponsor: Lantern Pharma Inc.

Sex: All

Age: 18+

Code: NCT05456256

Phase 2, Recruiting

Sacituzumab Govitecan With Bevacizumab Compared to Usual Chemotherapy (Carboplatin, Pegylated Liposomal Doxorubicin and Bevacizumab) for Treating Recurrent Platinum-Sensitive Ovarian Cancer After PARP Inhibitor Maintenance Therapy

for
Recurrent Platinum-Sensitive Fallopian Tube Endometrioid Adenocarcinoma,
Location: Danville IL, Urbana IL, Mattoon IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07504588

Phase 2, Recruiting

DNA Repair Activity in the Skin of Day and Night Shift Workers

for
Skin Cancer
Location: Fairborn OH
Sponsor: Wright State University

Sex: All

Age: 18 - 40

Code: NCT04122456

Recruiting

New MRI Biomarkers in Head and Neck Cancers

for
Head and Neck Cancer, Thyroid Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT03483337

Recruiting

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Metronomic Decitabine-Cedazuridine and Venetoclax in R/R AML, HR-MDS, HR/AP MPN

for
Relapsed / Refractory AML, High Risk Myelodysplastic Syndrome,
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 18+

Code: NCT07710534

Phase 2, Recruiting

A Pilot Study of ctDNA-Guided Immune Checkpoint Inhibitor Duration in Patients With Advanced Melanoma.

for
Melanoma (Skin Cancer)
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 70+

Code: NCT07830225

Recruiting

Photodynamic Diagnosis of Kidney Cancer Using Fluorescence Endoscopy and Oral 5-ALA

for
Kidney Cancers
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18 - 70+

Code: NCT07828704

Phase 2, Recruiting

PilotStudyAssessSafeActiveSurveillancApproachLocalThe Pa w/BrainMetsUndergoinCNSPenetratSystemicThe

for
Brain Cancer, Brain Cancer Metastatic, Nervous System Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07827001

Recruiting

Continuous Monitoring of Microvascular Anastomoses: An Observational Trial

for
Head and Neck Neoplasm
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07823283

Recruiting

Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a (Trastuzumab Deruxtecan), for Advanced Pancreatic Ductal Adenocarcinoma

for
Advanced Pancreatic Ductal Adenocarcinoma,
Location: Pittsburgh PA
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07619521

Phase 1, Phase 2, Recruiting

Characterization of the Melanoma-Specific Immune Response

for
Melanoma
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18 - 70+

Code: NCT00368615

Recruiting

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

for
Recurrent Small Cell Lung Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT07509034

Phase 1, Recruiting

Biopsy-site-marker in Breast Cancer

for
Breast Cancer
Location: Oklahoma City OK
Sponsor: University of Oklahoma

Sex: Female

Age: 18+

Code: NCT07833566

Recruiting

GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer

for
Pancreatic Cancer, Colorectal Cancer, Hepatocellular Carcinoma
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT07627191

Early Phase 1, Recruiting

Study of Cordycepin Plus Pentostatin in Patients With Refractory TdT-Positive Leukemia

for
Refractory TdT-Positive Leukemia
Location: Boston MA, San Antonio TX
Sponsor: OncoVista, Inc.

Sex: All

Age: 18+

Code: NCT00709215

Phase 1, Phase 2, Recruiting

Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment

for
Intracranial Meningioma
Location: Boston MA, New Haven CT, New York NY, Durham NC,
Sponsor: RTOG Foundation, Inc.

Sex: All

Age: 18+

Code: NCT06955169

Phase 2, Recruiting

A Study Evaluating a New Radiation Treatment Workflow (NGDS)

for
Lung Cancer (Diagnosis), Liver Cancer, Adult, Pancreatic Cancer,
Location: Cleveland OH, St Louis MO
Sponsor: Varian, a Siemens Healthineers Company

Sex: All

Age: 21+

Code: NCT07824583

Recruiting

Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

for
Head and Neck Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 0+

Code: NCT04428515

Recruiting

Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

for
Chest Wall Tumor, Breast Cancer, Lung Cancer, Esophageal Cancer,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07685938

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer