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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of the Dayspring Technology for Patients With Breast Cancer Related Lymphedema (BCRL) After Lymphatic Surgery

for
Lymphedema, Lymphedema, Breast Cancer, Lymphedema Arm
Location: Palo Alto CA
Sponsor: Koya Medical, Inc.

Sex: All

Age: 18+

Code: NCT04888975

Recruiting

The Effect of Beta-glucan in Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT00682032

Recruiting

A Phase I Cancer Vaccine Study for Patients With Metastatic Breast Cancer

for
Metastatic Breast Cancer
Location: Mobile AL
Sponsor: Southern Cancer Center

Sex: Female

Age: 18 - 70+

Code: NCT00715832

Phase1, Recruiting

A Study of Pre-Operative Cyberknife in Patients With Potentially Resectable Pancreas Cancer

for
Pancreas Cancer, Pancreatic Cancer,
Location: Camden NJ
Sponsor: The Cooper Health System

Sex: All

Age: 18+

Code: NCT02707315

Early_phase1, Recruiting

TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors

for
Renal Cell Cancer, Castrate Resistant Prostate Cancer,
Location: Louisville KY, Houston TX, Los Angeles CA
Sponsor: Portage Biotech

Sex: All

Age: 18+

Code: NCT04969315

Phase1, Phase2, Recruiting

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Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

for
Acute Myeloid Leukemia With Complex Karyotype,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07582172

Phase2, Recruiting

Role of Race in Nutritional Approach in Men on ADT

for
Prostate Cancer Metastatic Disease
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: Male

Age: 18+

Code: NCT06682390

Recruiting

Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer

for
Breast Cancer, Node-positive Breast Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06833502

Phase2, Recruiting

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

for
Glioblastoma Multiforme, Anaplastic Astrocytoma,
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 1 - 21

Code: NCT05956821

Phase1, Phase2, Recruiting

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma (PDAC), Cancer of Pancreas,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT03977233

Phase2, Recruiting

Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

for
Colorectal Cancer Metastatic
Location: Newport Beach CA, Los Angeles CA
Sponsor: Buzzard Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06634875

Phase2, Recruiting

Kidney Cancer DNA Registry

for
Renal Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT02087852

Recruiting

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

for
Lung Cancer, Small Cell Lung Carcinoma,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05620342

Early_phase1, Recruiting

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for
Malignant Solid Neoplasm
Location: Marshalltown IA, Ames IA, Boone IA, Fort Dodge IA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04871542

Recruiting

Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer

for
Cancer
Location: Stanford CA
Sponsor: Heike E Daldrup-Link

Sex: All

Age: 6 - 40

Code: NCT01542879

Phase1, Phase2, Recruiting

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

for
Early-stage Breast Cancer,
Location: Boston MA, Wichita KS, Fullerton CA, Whittier CA,
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04553770

Phase2, Recruiting

Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer

for
Bladder Cancer
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18+

Code: NCT06394570

Phase1, Phase2, Recruiting

PEN-866 in Patients With Advanced Solid Malignancies

for
Carcinoma, Endometrial Adenocarcinoma, Neoplasms,
Location: Philadelphia PA, Bethesda MD, Fairfax VA,
Sponsor: Tarveda Therapeutics

Sex: All

Age: 18+

Code: NCT03221400

Phase1, Phase2, Recruiting

Registry Study to Evaluate the Clinical Outcome of Cancer Patients and Benign Diseases Treated With Radiation

for
Cancer
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18 - 70+

Code: NCT03617237

Recruiting

Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer

for
Non-small Cell Lung Cancer
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT02570815

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer