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Oncology Clinical Trials

Browse 9,250 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Comparison of Between ThinSeed™ and OncoSeed™ for Permanent Prostate Brachytherapy

for
Prostate Cancer
Location: Westmont IL
Sponsor: Prostate Cancer Foundation of Chicago

Sex: Male

Age: 40+

Code: NCT01379742

Recruiting

A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

for
Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia,
Location: Miami FL, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06566742

Phase 2, Recruiting

Liver Transplantation in Intrahepatic Cholangiocarcinoma

for
Intrahepatic Cholangiocarcinoma,
Location: Newark NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 70+

Code: NCT06140134

Recruiting

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: New York NY, Philadelphia PA, Durham NC, Toronto,
Sponsor: Syndax Pharmaceuticals

Sex: All

Age: 0+

Code: NCT04065399

Phase 1, Phase 2, Recruiting

Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy

for
Acute Myeloid Leukemia, IDH1 Mutation
Location: Miami FL
Sponsor: Justin Watts, MD

Sex: All

Age: 18 - 70+

Code: NCT06782542

Phase 2, Recruiting

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Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

for
Diffuse Large B-Cell Lymphoma
Location: Towson MD, Beltsville MD, Jacksonville FL, Detroit MI,
Sponsor: AstraZeneca

Sex: All

Age: 65 - 70+

Code: NCT05952024

Phase 2, Recruiting

Groningen International Study on Sentinel Nodes in Vulvar Cancer-III

for
Vulvar Cancer, Sentinel Lymph Node, Lymph Node Metastases
Location: Providence RI, Springfield MA, Commack NY, Uniondale NY,
Sponsor: University Medical Center Groningen

Sex: Female

Age: 18+

Code: NCT05076942

Phase 2, Recruiting

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

for
Bone Metastases, Lymphoma, Multiple Myeloma, Opioid Use, Pain
Location: St Louis MO
Sponsor: St. Louis University

Sex: All

Age: 18+

Code: NCT03823534

Phase 3, Recruiting

Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in Veterans

for
Barrett Esophagus, GERD, Obesity, Esophageal Cancer
Location: Cleveland OH
Sponsor: Cleveland VA Medical Research and Education Foundation

Sex: All

Age: 40 - 70+

Code: NCT05210049

Recruiting

A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

for
Acute Myeloid Leukemia,
Location: Boston MA, Baltimore MD, Aventura FL, Chapel Hill NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05886049

Phase 1, Recruiting

Comprehensive Analysis Platform To Understand, Remedy and Eliminate ALS

for
Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis,
Location: Quebec, Montreal, Toronto, Edmonton
Sponsor: University of Alberta

Sex: All

Age: 18+

Code: NCT05204017

Recruiting

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

for
Relapsed/Refractory Multiple Myeloma
Location: Boston MA, Stony Brook NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05850234

Phase 1, Phase 2, Recruiting

Internet-Delivered Pain Self-Management for Persons With Acute Recurrent and Chronic Pancreatitis Pain

for
Pancreatitis, Chronic Pancreatitis,
Location: Seattle WA
Sponsor: Seattle Children's Hospital

Sex: All

Age: 18+

Code: NCT06386224

Recruiting

A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)

for
Myelodysplastic Syndrome, Acute Myeloid Leukemia
Location: Tampa FL, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06616636

Phase 1, Recruiting

reSET for the Treatment of Stimulant Use in HIV Clinics: Care Optimization Supporting Treatment Adherence (COSTA)

for
Stimulant Use Disorder, People Living With HIV
Location: Miami FL
Sponsor: University of Miami

Sex: Male

Age: 18 - 70+

Code: NCT05958017

Recruiting

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

for
B-cell Acute Lymphoblastic Leukemia,
Location: Boston MA, Buffalo NY, Chicago IL
Sponsor: Marlise Luskin, MD

Sex: All

Age: 18+

Code: NCT03595917

Phase 1, Recruiting

Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitor

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Female

Age: 18+

Code: NCT05065021

Phase 2, Recruiting

A Study to Investigate CYC140, in Subjects With Advanced Solid Tumors and Lymphoma

for
Solid Tumor, Adult Lymphoma
Location: Pittsburgh PA, Houston TX, Duarte CA
Sponsor: Cyclacel Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05358379

Phase 1, Phase 2, Recruiting

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

for
Acute Leukemia, Myelodysplastic Syndrome,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 70+

Code: NCT06265584

Phase 2, Recruiting

A Qualitative Assessment of the Severity and Impact of Rheumatic Immune-Related Adverse Events Following Immune Checkpoint Inhibitor Immunotherapy

for
Arthritis, Polymyalgia Rheumatica, Immune Checkpoint Inhibitors
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06647134

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer