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Sickle Cell Clinical Trials

Browse 133 sickle cell clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease

for
Sickle Cell Disease
Location: Augusta GA
Sponsor: Abdullah Kutlar

Sex: All

Age: 18+

Code: NCT01245179

Phase1, Recruiting

Investigation of the Genetics of Hematologic Diseases

for
Bone Marrow Failure Syndromes, Erythrocyte Disorder,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT02720679

Recruiting

Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease

for
Sickle Cell Disease, Vaso-occlusive Pain Episode
Location: Washington D.C. DC
Sponsor: Suvankar Majumdar

Sex: All

Age: 4 - 21

Code: NCT06635902

Phase2, Recruiting

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

for
Sickle Cell Disease, Vaso-occlusive Crisis
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 6 - 25

Code: NCT03353584

Recruiting

Cerebral Oxygen Metabolism in Children

for
Sickle Cell Disease, Cerebral Stroke
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 3 - 50

Code: NCT04157179

Recruiting

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Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease

for
Sickle Cell, PKLR Variants, Adenosine Triphosphate Activities
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT03685721

Recruiting

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

for
Sickle Cell Disease
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 18 - 21

Code: NCT05583721

Phase2, Recruiting

A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease

for
Sickle Cell Disease
Location: Chicago IL
Sponsor: EpiDestiny, Inc.

Sex: All

Age: 18+

Code: NCT04055818

Phase1, Recruiting

A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

for
Sickle Cell Disease, Thalassemia, Beta, Thalassemia
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 2 - 50

Code: NCT05736419

Phase2, Recruiting

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

for
Alpha and Beta Thalassemia, Sickle Cell Disease, Malaria,
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 70

Code: NCT03937817

Recruiting

Cutaneous Hydration Assessment in SCD

for
Sickle Cell Disease
Location: Pittsburgh PA
Sponsor: Enrico Novelli

Sex: All

Age: 12+

Code: NCT05210114

Recruiting

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

for
Sickle Cell Anemia, Beta-thalassemia Major,
Location: Pittsburgh PA
Sponsor: Paul Szabolcs

Sex: All

Age: 5 - 40

Code: NCT03653338

Phase1, Phase2, Recruiting

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

for
Severe Sickle Cell Disease, Bone Marrow Failure Syndromes,
Location: New Haven CT, Wilmington DE, Grand Rapids MI,
Sponsor: Washington University School of Medicine

Sex: All

Age: 0 - 21

Code: NCT03128996

Phase1, Phase2, Recruiting

Low Systemic/High Local Exercise Load in Peds SCD

for
Sickle Cell Anemia in Children
Location: Jackson MS
Sponsor: University of Mississippi Medical Center

Sex: All

Age: 12 - 17

Code: NCT06387758

Recruiting

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

for
Sickle Cell Disease, Thalassemia
Location: New York NY, Durham NC, Atlanta GA, Chicago IL,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 2+

Code: NCT06609226

Phase3, Recruiting

Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

for
Sickle Cell Disease,
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT06184126

Recruiting

Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

for
Sickle Cell Disease, Sickle Cell Anemia
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT04093986

Recruiting

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

for
Beta-Thalassemia, Thalassemia, Hematologic Diseases,
Location: New York NY, Charlotte NC, Nashville TN
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 12 - 35

Code: NCT05477563

Phase3, Recruiting

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

for
Sickle Cell Disease
Location: Boston MA, Queens NY, The Bronx NY, Brooklyn NY,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 12+

Code: NCT06612268

Phase3, Recruiting

Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease

for
Sickle Cell Disease
Location: New York NY, Washington D.C. DC, Toronto, Charlotte NC,
Sponsor: Robert Nickel

Sex: All

Age: 2 - 25

Code: NCT03587272

Phase2, Recruiting