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Sickle Cell Clinical Trials

Browse 133 sickle cell clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease

for
Sickle Cell Disease, Executive Dysfunction,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 8 - 17

Code: NCT07226219

Phase1, Recruiting

Writing Relaxing Beats in Adolescents Who Have Sickle Cell Disease

for
Sickle Cell Disease
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 11 - 18

Code: NCT07222475

Recruiting

Optimizing Hydroxyurea Dosage With Pharmakokinetic in Patients Suffering of Moderate to Severe Sickle Cell Anemia

for
Sickle Cell Disease (SCD)
Location: Montreal
Sponsor: Yves Pastore

Sex: All

Age: 0 - 18

Code: NCT06761560

Phase2, Phase3, Recruiting

Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype

for
Sickle Cell Disease, Sickle Cell Anaemia, Sickle Cell Anemia
Location: Toronto
Sponsor: Biossil Inc.

Sex: All

Age: 16 - 35

Code: NCT07282210

Phase2, Recruiting

Early Screening and Treatment of Heart Complication in Sickle Cell Disease

for
Sickle Cell Disease
Location: Falls Church VA, Fairfax VA
Sponsor: Inova Health Care Services

Sex: All

Age: 18+

Code: NCT07023666

Phase2, Recruiting

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Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease

for
Sickle Cell Disease
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 22

Code: NCT07616154

Phase2, Recruiting

Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial

for
Sickle Cell Disease
Location: Oakland CA
Sponsor: University of California, San Francisco

Sex: All

Age: 15 - 40

Code: NCT06260891

Phase2, Recruiting

Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)

for
Sickle Cell Disease
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 8+

Code: NCT05810181

Recruiting

Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease

for
Sickle Cell Disease, Hemolytic Anemia
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT07566494

Phase1, Recruiting

Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)

for
Sickle Cell Anemia (HbSS), Sickle-β0-thalassemia (HbSβ0)
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT07177300

Recruiting

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

for
Sickle Cell Disease, Beta-thalassemia
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 4 - 65

Code: NCT07599176

Phase1, Phase2, Recruiting

ATHNdataset Registry

for
Hemophilia, Thrombosis, Hemophilia A, Hemophilia B,
Location: Hickory NC
Sponsor: American Thrombosis and Hemostasis Network

Sex: All

Age: 0+

Code: NCT06820515

Recruiting

Trans-auricular Nerve Stimulation as an Innovative Approach to the Treatment of Pain in Pediatric Patients Suffering From Sickle Cell Disease

for
Sickle Cell Disease
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 7 - 18

Code: NCT07090668

Recruiting

Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait

for
Sickle Cell Disease, Sickle Cell Trait
Location: Farmington CT
Sponsor: UConn Health

Sex: Female

Age: 50+

Code: NCT07083531

Recruiting

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

for
Sickle Cell Trait
Location: Wilmington DE, Greenville NC, Durham NC, Chapel Hill NC,
Sponsor: National Alliance for Sickle Cell Centers

Sex: All

Age: 18+

Code: NCT06071377

Recruiting

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

for
Sickle Cell Disease (SCD),
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: Female

Age: 18 - 50

Code: NCT06665997

Recruiting

Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)

for
Sickle Cell Disease
Location: Cleveland OH
Sponsor: University Hospitals Cleveland Medical Center

Sex: All

Age: 12+

Code: NCT02824471

Recruiting

Cannabidiol in Sickle Cell Disease

for
Sickle Cell Disease
Location: Manhattan NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18+

Code: NCT06930703

Phase1, Phase2, Recruiting

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

for
Sickle Cell Disorders, Sickle Cell Disease, Hemoglobin S,
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 65

Code: NCT05904093

Phase1, Recruiting

Functional Ovarian Reserve in Sickle Cell Disease

for
Sickle Cell Disease
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: Female

Age: 10 - 18

Code: NCT07392216

Recruiting