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Sickle Cell Clinical Trials

Browse 133 sickle cell clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Cerebrovascular Reactivity Measurements With High-Density Diffuse Optical Tomography

for
Sickle Cell Disease, Cerebral Stroke
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 6 - 70

Code: NCT07776444

Recruiting

Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing

for
Sickle Cell Disease
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 8 - 18

Code: NCT07562451

Recruiting

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

for
Sickle Cell Disease,
Location: Boston MA
Sponsor: Daniel Bauer

Sex: All

Age: 13 - 40

Code: NCT06647979

Phase1, Recruiting

Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0

for
Sickle Cell Disease, Pain, Acupuncture,
Location: Cincinnati OH
Sponsor: University of Cincinnati

Sex: All

Age: 14 - 70+

Code: NCT06725550

Recruiting

Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease

for
Sickle Cell Disease
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 1 - 30

Code: NCT03279094

Phase1, Recruiting

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SickleFit Exercise and Nutrition Study

for
Sickle Cell Disease, Aging
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 35+

Code: NCT07442851

Recruiting

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

for
Sickle Cell Disease
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 8 - 25

Code: NCT06555939

Recruiting

Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease

for
Sickle Cell Disease
Location: Columbus OH, Nashville TN, Chicago IL, St Louis MO
Sponsor: Ohio State University

Sex: All

Age: 18+

Code: NCT06919224

Recruiting

Allo HSCT for High Risk Hemoglobinopathies

for
Graft Failure, Sickle Cell Disease, Hemoglobinopathies
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 0 - 55

Code: NCT06872333

Phase2, Recruiting

Early Life Exposures Among Children With Sickle Cell Disease

for
Sickle Cell Disease, Adverse Childhood Experiences,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: Female

Age: 18 - 50

Code: NCT05377372

Recruiting

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

for
Sickle Cell Disease Vaso-occlusive Crisis
Location: The Bronx NY, New York NY, Baltimore MD, Greenville NC,
Sponsor: CSL Behring

Sex: All

Age: 12+

Code: NCT06699849

Phase2, Recruiting

Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease

for
Sickle Cell Disease, Pregnancy Related
Location: Atlanta GA
Sponsor: Emory University

Sex: Female

Age: 18+

Code: NCT06979492

Recruiting

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

for
Sickle Cell Disease
Location: The Bronx NY, New York NY, New Brunswick NJ,
Sponsor: Pfizer

Sex: All

Age: 12+

Code: NCT05431088

Phase2, Phase3, Recruiting

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

for
Sickle Cell Disease
Location: The Bronx NY, Bethesda MD, Richmond VA, Hollywood FL,
Sponsor: CSL Behring

Sex: All

Age: 18+

Code: NCT07224360

Phase2, Recruiting

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

for
Sickle Cell Disease, Sickle Cell Anemia, Osteonecrosis,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18 - 70+

Code: NCT06016634

Phase2, Recruiting

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

for
Sickle Cell Disease,
Location: Torrance CA
Sponsor: Mohsen Saidinejad

Sex: All

Age: 5 - 20

Code: NCT07369024

Phase2, Recruiting

Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease

for
Sickle Cell Disease, Measles Vaccination, Sickle Cell Anemia
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0 - 6

Code: NCT07356050

Recruiting

Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

for
Sickle Cell Disease
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 13+

Code: NCT04416178

Recruiting

A Long-term Follow-up Study in Patients Who Received BEAM-101

for
Hemoglobinopathy, Sickle Cell Disease
Location: Boston MA
Sponsor: Beam Therapeutics Inc.

Sex: All

Age: 14 - 37

Code: NCT07373639

Recruiting

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

for
Sickle Cell Disease
Location: New York NY, Greenville NC, Durham NC, Pittsburgh PA,
Sponsor: Disc Medicine, Inc

Sex: All

Age: 18+

Code: NCT07187973

Phase1, Recruiting