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AstraZeneca Clinical Trials

Find clinical trials for AstraZeneca. Search for AstraZeneca clinical trials in different cities and states across the United States.

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Active & ResponsiveNew

Study of Safety and PK of AZD0543 in Healthy Adults

for
Human Metapneumovirus Infection
Location: South Miami FL
Sponsor: AstraZeneca

Sex: All

Age: 18 - 55

Code: NCT07824622

Phase1, Recruiting
Active & ResponsiveNew

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

for
Heart Failure With Preserved Ejection Fraction (HFpEF),
Location: The Bronx NY, Brooklyn NY, Kingston, Miami Lakes FL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07761117

Phase3, Recruiting
Active & ResponsiveNew

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

for
Chronic Kidney Disease
Location: Toronto, Waterloo, Minneapolis MN, Arlington TX,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07753993

Phase3, Recruiting
Active & ResponsiveNew

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

for
Obesity or Overweight, Weight-Related Comorbidity,
Location: Montreal, Joliette, Stouffville, Statesville NC,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07776509

Phase3, Recruiting
Active & ResponsiveNew

A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Laroprovstat, Rosuvastatin and Placebo on LDL-C in LLT-naïve Patients.

for
Hypercholesterolaemia
Location: Sherbrooke, Millville NJ, Stouffville,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07619131

Phase3, Recruiting

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Active & Responsive

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

for
Obesity or Overweight
Location: Stouffville, Mississauga
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07784725

Phase3, Recruiting
Active & Responsive

A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants With Relapsed or Refractory Multiple Myeloma

for
Relapsed or Refractory Multiple Myeloma
Location: Duarte CA
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07681596

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers

for
Healthy Participants
Location: Glendale CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 55

Code: NCT06951880

Phase1, Recruiting
Active & Responsive

Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment

for
Asthma, Eosinophilic Granulomatosis With Polyangiitis (EGPA),
Location: Toronto
Sponsor: AstraZeneca

Sex: All

Age: 6+

Code: NCT07444567

Phase3, Recruiting
Active & Responsive

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin

for
Type 2 Diabetes Mellitus
Location: Toronto, Ocoee FL, Vancouver
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07664553

Phase3, Recruiting
Active & Responsive

An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC

for
High-risk Muscle Invasive Urothelial Carcinoma
Location: Hamilton, Barrie
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07720284

Phase3, Recruiting
Active & Responsive

An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for
Stomatitis
Location: Wynnewood PA, East Syracuse NY, Wilson NC, Athens GA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07357597

Recruiting
Active & Responsive

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

for
Relapsed Refractory Multiple Myeloma
Location: New Haven CT, New York NY, Montreal, Winston-Salem NC,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07391657

Phase3, Recruiting
Active & Responsive

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

for
Sub-study 1 Cervical Cancer (Volrustomig Monotherapy),
Location: Stony Brook NY, New York NY, Montreal, Baltimore MD,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06535607

Phase2, Recruiting
Active & Responsive

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

for
Healthy Participants, Obesity
Location: Glendale CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 65

Code: NCT07511205

Phase1, Recruiting
Active & Responsive

Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)

for
Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated IGHV,
Location: Toronto, Calgary
Sponsor: AstraZeneca

Sex: All

Age: 18

Code: NCT07509151

Phase3, Recruiting
Active & Responsive

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for
Metastatic Castration-resistant Prostate Cancer
Location: Montreal, Miami FL, Dothan AL, Metairie LA, Omaha NE,
Sponsor: AstraZeneca

Sex: Male

Age: 18+

Code: NCT07611110

Phase3, Recruiting
New

A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)

for
Renal Insufficiency, Chronic
Location: Savannah GA, Charlotte NC, Waterloo, Riverview FL,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07624305

Phase3, Recruiting
New

QUARTZ: Comparative Effectiveness of Switching From Albuterol to Albuterol/Budesonide Versus Adding Low-dose ICS or LTRA to Albuterol

for
Asthma
Location: Wilmington DE
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07787117

Recruiting
New

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

for
Obesity or Overweight, Diabetes Mellitus, Type 2
Location: Truro, Quebec, Norfolk VA, Stouffville, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07784270

Phase3, Recruiting