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AstraZeneca Clinical Trials

Find clinical trials for AstraZeneca. Search for AstraZeneca clinical trials in different cities and states across the United States.

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Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations

for
Transthyretin Amyloidosis,
Location: Vancouver, Los Angeles CA
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07654855

Recruiting
New

Study of the Effect of Haemodialysis on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone/Dapagliflozin

for
Kidney Failure
Location: Orlando FL
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07754331

Phase1, Recruiting
New

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

for
Type 2 Diabetes Mellitus,
Location: Raleigh NC, Miami Lakes FL, Ocoee FL, Gaffney SC,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07662135

Phase3, Recruiting

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for
HER2-positive Gastric Cancer,
Location: Chicoutimi, New York NY, Summit NJ, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06764875

Phase3, Recruiting

Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

for
Chronic Lymphocytic Leukaemia,
Location: Philadelphia PA, Columbus OH
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06651970

Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Sydney, Saint John, Scarborough ME, West Haven CT,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06692738

Phase3, Recruiting

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Location: Fairhaven MA, Boston MA, Stony Brook NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06129864

Phase3, Recruiting

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

for
Moderate Hepatic Impairment
Location: San Antonio TX, Rialto CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07343960

Phase1, Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

for
Systemic Lupus Erythematosus,
Location: Sherbrooke, Anniston AL, Iowa City IA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70

Code: NCT06916806

Phase1, Recruiting

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

for
Non-small Cell Lung Cancer,
Location: Boston MA, New York NY, New Brunswick NJ, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05877599

Phase1, Recruiting

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-Resistant Prostate Cancer
Location: Boston MA, Miami FL, Tampa FL, Chicago IL, Omaha NE
Sponsor: AstraZeneca

Sex: Male

Age: 18+

Code: NCT06879041

Phase1, Recruiting

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

for
Diffuse Large B-Cell Lymphoma
Location: Des Moines IA, Tacoma WA
Sponsor: AstraZeneca

Sex: All

Age: 65 - 70+

Code: NCT05952024

Phase2, Recruiting

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

for
Relapsed/Refractory Multiple Myeloma
Location: Boston MA, Stony Brook NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05850234

Phase1, Phase2, Recruiting

AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia

for
B-cell Acute Lymphoblastic Leukemia (B-ALL)
Location: New York NY, Richmond VA, Tampa FL, Atlanta GA,
Sponsor: AstraZeneca

Sex: All

Age: 12+

Code: NCT06137118

Phase1, Phase2, Recruiting

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for
Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma,
Location: Boston MA, Providence RI, New York NY, Hackensack NJ,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06564038

Phase1, Phase2, Recruiting

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Boston MA, New Haven CT, Montreal, Baltimore MD,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05061550

Phase2, Recruiting

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Trenton NJ, Montreal, Baltimore MD, Washington D.C. DC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06792695

Phase2, Recruiting

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

for
Gastric Cancer, Gastroesophageal Junction Cancer,
Location: Providence RI, Sherbrooke, Commack NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06219941

Phase2, Recruiting

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

for
B-cell Malignancies
Location: New York NY, Hackensack NJ, Montreal, Winston-Salem NC,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06542250

Phase1, Phase2, Recruiting

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

for
Biliary Tract Cancer
Location: Halifax, White Plains NY, Montreal, Towson MD,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06467357

Phase3, Recruiting