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AstraZeneca Clinical Trials

Find clinical trials for AstraZeneca. Search for AstraZeneca clinical trials in different cities and states across the United States.

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Observational Study Protocol: LIVER-R

for
Hepatobiliary Cancers
Location: Halifax, Boston MA, White Plains NY, Philadelphia PA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06252753

Recruiting

A Study of AZD3470, a PRMT5 Inhibitor, Given as Monotherapy and in Combination in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors

for
Advanced Solid Tumors That Are MTAP Deficient
Location: Providence RI, New Haven CT, Baltimore MD, Fairfax VA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06130553

Phase1, Phase2, Recruiting

Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC

for
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Location: Montreal, Baltimore MD, Fairfax VA, Houston TX,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT04686305

Phase1, Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: North Dartmouth MA, Quebec, Toms River NJ,
Sponsor: AstraZeneca

Sex: All

Age: 40 - 70+

Code: NCT06883305

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: New Britain CT, Staten Island NY, Colchester VT,
Sponsor: AstraZeneca

Sex: All

Age: 40 - 70+

Code: NCT06878261

Phase3, Recruiting

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A Trial to Investigate Benralizumab in Children With Eosinophilic Diseases

for
Eosinophilic Granulomatosis With Polyangiitis (EGPA),
Location: Toronto, Highland Hills OH, Aurora CO
Sponsor: AstraZeneca

Sex: All

Age: 6 - 17

Code: NCT06512883

Phase3, Recruiting

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

for
Endometrial Cancer, Gastric Cancer,
Location: Commack NY, East Brunswick NJ, Columbus OH,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05489211

Phase2, Recruiting

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: New Haven CT, Brooklyn NY, New York NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06350097

Phase3, Recruiting

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

for
B-cell Non-Hodgkin Lymphoma, Follicular Lymphoma (FL),
Location: New York NY, Philadelphia PA, Ottawa, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06526793

Phase2, Recruiting

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for
Non-Small Cell Lung Cancer
Location: St. John's, Rimouski, Boston MA, Levis, Stony Brook NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06357533

Phase3, Recruiting

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

for
Multiple Myeloma
Location: Boston MA, New York NY, Montreal, Philadelphia PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06106945

Phase1, Phase2, Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for
Non-squamous Non-small Cell Lung Cancer
Location: Saint John, South Portland ME, West Haven CT,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06627647

Phase3, Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

for
Carcinoma, Non-Small Cell Lung
Location: Westbury NY, Fresh Meadows NY, Philadelphia PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06868277

Phase3, Recruiting

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)

for
Locally Advanced Cervical Cancer
Location: Montreal, Toronto, Hamilton
Sponsor: AstraZeneca

Sex: Female

Age: 15+

Code: NCT06079671

Phase3, Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

for
Hyperkalaemia
Location: Montreal, Baltimore MD, Columbia SC, Cincinnati OH,
Sponsor: AstraZeneca

Sex: All

Age: 0 - 18

Code: NCT03813407

Phase3, Recruiting

Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors

for
Gastric Cancer, Gastro-esophageal Junction Cancer,
Location: Jacksonville FL, Rochester MN
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06005493

Phase1, Phase2, Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for
Heart Failure and Impaired Kidney Function
Location: Sydney, Boston MA, Providence RI, Worcester MA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06307652

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

for
Polymyositis, Dermatomyositis
Location: Boston MA, New Haven CT, Great Neck NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06455449

Phase3, Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Providence RI, New Haven CT, Quebec, Stony Brook NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase3, Recruiting

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

for
Viral Lung Infection and Acute Respiratory Failure
Location: Levis, Quebec, New York NY, Montreal, Annapolis MD,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05624450

Phase3, Recruiting