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AstraZeneca Clinical Trials

Find clinical trials for AstraZeneca. Search for AstraZeneca clinical trials in different cities and states across the United States.

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Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

for
Urinary Bladder Neoplasms, Immune Checkpoint Inhibitors,
Location: Quebec, Sherbrooke, Hamilton
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06960577

Phase3, Recruiting

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for
Endometrial Cancer, Malignant Solid Tumour
Location: Scarborough ME, Stony Brook NY, White Plains NY,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT07044336

Phase3, Recruiting

A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234

for
Hepatic Impairment
Location: Miami Lakes FL, San Antonio TX, Chandler AZ, Rialto CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07546760

Phase1, Recruiting

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for
Non-small Cell Lung Cancer, Colorectal Carcinoma,
Location: Boston MA, New York NY, Philadelphia PA, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06218914

Phase1, Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of AZD1613 in Healthy Participants.

for
Healthy
Location: Glendale CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 50

Code: NCT06995820

Phase1, Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for
Cardiovascular Disease
Location: Sydney, Halifax, Bridgewater, Bangor ME, Scarborough ME,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07000357

Phase3, Recruiting

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

for
Hepatocellular Carcinoma
Location: New Haven CT, Quebec, New York NY, New Brunswick NJ,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06921785

Phase3, Recruiting

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

for
Staphylococcus Aureus
Location: Ridgewood NY, Jersey City NJ, Bethlehem PA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 55

Code: NCT06749457

Phase1, Phase2, Recruiting

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Truro, Burlington MA, Quebec, Sherbrooke, Victoriaville,
Sponsor: AstraZeneca

Sex: All

Age: 40+

Code: NCT07082738

Phase2, Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort

for
Chronic Kidney Disease
Location: Chicago IL, Saint Paul MN, San Antonio TX, Glendale CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07024823

Phase1, Recruiting

A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma

for
Gastroesophageal Adenocarcinoma
Location: New York NY, Montreal, Newark DE, Washington D.C. DC,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07069712

Phase2, Recruiting

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis

for
ATTR Amyloidosis
Location: Calgary
Sponsor: AstraZeneca

Sex: All

Age: 0+

Code: NCT06355934

Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia

for
Healthy Participants, Dyslipidemia
Location: Brooklyn MD, Port Orange FL, Jacksonville FL,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70

Code: NCT06980428

Phase1, Recruiting

A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for
Multiple Myeloma
Location: New York NY, Charlottesville VA, Atlanta GA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07073547

Phase1, Recruiting

A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity

for
Healthy Participants
Location: Brooklyn MD, Glendale CA
Sponsor: AstraZeneca

Sex: Female

Age: 35 - 70+

Code: NCT07013643

Phase1, Recruiting

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for
Systemic Lupus Erythematosus
Location: New Hyde Park NY, Valhalla NY, The Bronx NY,
Sponsor: AstraZeneca

Sex: All

Age: 5 - 17

Code: NCT05835310

Phase3, Recruiting

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

for
Melanoma, Non-small Cell Lung Cancer,
Location: Fairfax VA, Pittsburgh PA, Grand Rapids MI, St Louis MO,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07115043

Phase1, Phase2, Recruiting

LUNG-ROLL: Treatment Patterns and Cost of Illness of Lung Cancer in Canada

for
Lung Neoplasms
Location: Toronto, Calgary
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07143110

Recruiting

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

for
Breast Cancer, Early Breast Cancer
Location: Winston-Salem NC, Irving TX, Aberdeen SD, Pierre SD
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05774951

Phase3, Recruiting

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

for
Advanced Breast Cancer
Location: Boston MA, Stony Brook NY, Mineola NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06380751

Phase3, Recruiting