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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for
Extrapulmonary Neuroendocrine Cancer (epNEC)
Location: Duarte CA, St Louis MO, Nashville TN, Atlanta GA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07544654

Phase3, Recruiting

REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma

for
Metastatic Castration-Resistant Prostate Cancer (mCRPC),
Location: Duarte CA, Goodyear AZ, Houston TX, Zion IL, Tampa FL
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07594106

Phase1, Phase2, Recruiting

Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

for
Glaucoma, Ocular Surface Disease
Location: Fountain Valley CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 0+

Code: NCT04354545

Recruiting

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

for
HIV Infections
Location: Los Angeles CA, Beverly Hills CA, West Hollywood CA,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT07473778

Recruiting

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

for
HIV Infections
Location: West Hollywood CA, Palm Springs CA, Bakersfield CA,
Sponsor: ViiV Healthcare

Sex: All

Age: 18+

Code: NCT07202546

Phase2, Recruiting

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Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

for
Acute Promyelocytic Leukemia (APL),
Location: Duarte CA, Los Angeles CA, Stanford CA, Houston TX,
Sponsor: Quetzal Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07504458

Phase3, Recruiting

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for
Solid Tumor, Non-Small Cell Lung Cancer, Head and Neck Cancer,
Location: Duarte CA, Glendale CA, Los Angeles CA, Murrieta CA,
Sponsor: Inhibrx Biosciences, Inc

Sex: All

Age: 18+

Code: NCT04198766

Phase1, Phase2, Recruiting
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A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Denver CO, Grand Rapids MI,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07409246

Phase1, Recruiting

Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)

for
Retinitis Pigmentosa, Stargardt Macular Dystrophy,
Location: Irvine CA
Sponsor: Ray Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07502664

Recruiting

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

for
Open Angle Glaucoma (OAG),
Location: Glendale CA, Charleston SC, New York NY, Boston MA
Sponsor: Life Biosciences Inc.

Sex: All

Age: 40 - 70+

Code: NCT07290244

Phase1, Recruiting

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease

for
Steroid Refractory GVHD
Location: Duarte CA, Los Angeles CA, St Louis MO, Cincinnati OH,
Sponsor: ReAlta Life Sciences, Inc.

Sex: All

Age: 12+

Code: NCT06343792

Phase2, Recruiting

Patient Interest in an Integrative Oncology Program at USC Norris Cancer Center: A Single-Institution Needs Assessment

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07306338

Recruiting

Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

for
Chronic Graft Versus Host Disease
Location: Duarte CA, Seattle WA, Tampa FL, New York NY, Boston MA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT05996627

Phase2, Recruiting

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

for
Stomach Cancer Stage IV, Esophagus Cancer, Stomach Cancer
Location: Santa Monica CA, Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07070466

Phase2, Recruiting

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

for
AIDS-Related Diffuse Large B-cell Lymphoma,
Location: Duarte CA, Salt Lake City UT, Chicago IL, Columbus OH,
Sponsor: AIDS Malignancy Consortium

Sex: All

Age: 18+

Code: NCT05077527

Phase1, Recruiting

An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to Ruxolitinib

for
Myelofibrosis
Location: Duarte CA, Seattle WA, Houston TX, Ann Arbor MI,
Sponsor: Kartos Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT04485260

Phase1, Phase2, Recruiting

A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

for
Hepatocellular Carcinoma (HCC)
Location: Duarte CA, Portland OR, Nashville TN, Hackensack NJ
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07291076

Phase1, Phase2, Recruiting

Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers

for
Metastatic Pancreatic Adenocarcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06524973

Recruiting

Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

for
Metastatic Non-Squamous Non-Small Cell Lung Cancer,
Location: Los Angeles CA, Birmingham AL, Durham NC, New York NY,
Sponsor: CatalYm GmbH

Sex: All

Age: 18+

Code: NCT07246863

Phase2, Recruiting

Postpartum Continuous Glucose Monitoring for Type 2 Diabetes Mellitus Risk Evaluation in Patients With Gestational Diabetes Mellitus: POSTPOD Trial

for
Gestational Diabetes Mellitus in Pregnancy
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: Female

Age: 18+

Code: NCT07449039

Recruiting