Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
Recombinant Erwinia Asparaginase and Venetoclax in Combination With Blinatumomab for the Treatment of Relapsed or Refractory CD19 Positive B-cell Acute Lymphoblastic Leukemia
for
Recurrent B Acute Lymphoblastic Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 12 - 55
Code: NCT07133997
Phase1, Recruiting
A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
for
Myeloproliferative Neoplasms
Location: Duarte CA, Palo Alto CA, Westwood KS, Houston TX,
Sponsor: Incyte Corporation
Sex: All
Age: 18+
Code: NCT06034002
Phase1, Recruiting
Empowering Youth With School Discipline Referrals as Peer Coaches
for
Disruptive Behavior
Location: Los Angeles CA
Sponsor: University of Southern California
Sex: All
Age: 10 - 15
Code: NCT07515742
Recruiting
CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDS
for
HIV-1
Location: Duarte CA, San Diego CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06252402
Early_phase1, Recruiting
Mobile Vehicle-Based Delivery of Lenacapavir Pre-Exposure Prophylaxis in Los Angeles County
for
HIV Prevention
Location: Santa Monica CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 18+
Code: NCT07467018
Recruiting
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Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer
for
Breast Carcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: Female
Age: 21+
Code: NCT04913064
Recruiting
Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin Lymphoma Patients Ineligible for Standard Treatment
for
Classic Hodgkin Lymphoma
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT07275216
Phase2, Recruiting
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes
for
Type 2 Diabetes
Location: Canoga Park CA, Las Vegas NV, San Antonio TX,
Sponsor: Housey Healthcare ULC
Sex: All
Age: 18+
Code: NCT07546929
Phase2, Recruiting
A Clinical Study Evaluating Licaminlimab for Dry Eye Disease
for
Dry Eye Disease (DED)
Location: Newport Beach CA, Garden Grove CA, Aliso Viejo CA,
Sponsor: Oculis
Sex: All
Age: 18+
Code: NCT07548632
Phase2, Phase3, Recruiting
Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma
for
Mantle Cell Lymphoma
Location: Duarte CA, Ann Arbor MI, Charlottesville VA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT03523975
Phase1, Phase2, Recruiting
Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)
for
Metastatic Malignant Solid Neoplasm, Lymphoma
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT05371132
Phase1, Recruiting
Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma
for
Marginal Zone Lymphoma
Location: Duarte CA, Nashvile TN, Atlanta GA, Miami FL
Sponsor: University of Miami
Sex: All
Age: 18+
Code: NCT05296070
Phase2, Recruiting
A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: Duarte CA, Houston TX, New York NY
Sponsor: Edgewood Oncology Inc.
Sex: All
Age: 18+
Code: NCT04243785
Phase1, Recruiting
A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)
for
Stress Urinary Incontinence (SUI)
Location: Los Angeles CA, Stanford CA, San Francisco CA,
Sponsor: UroMems SAS
Sex: Male
Age: 22+
Code: NCT06968741
Recruiting
New
Environmental Exposure Assessment in High-Risk and Early-Onset Breast Cancer Care
for
Breast Carcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: Female
Age: 18+
Code: NCT07690852
Recruiting
New
First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors
for
Advanced Solid Tumors
Location: Duarte CA, San Antonio TX, Grand Rapids MI, Fairfax VA
Sponsor: VelaVigo Bio Inc
Sex: All
Age: 18+
Code: NCT07700160
Phase1, Phase2, Recruiting
ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1
for
Depressed Mood
Location: Laguna Hills CA, La Jolla CA
Sponsor: Salma Health, Inc.
Sex: All
Age: 18+
Code: NCT07528014
Recruiting
A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression
for
Ovarian Cancer
Location: Torrance CA, Beverly Hills CA
Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Sex: Female
Age: 18+
Code: NCT07546500
Phase3, Recruiting
AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.
for
Lymphoma, Non-Hodgkin Lymphoma, Hodgkin Lymphoma,
Location: Duarte CA, Houston TX, Miami FL, Philadelphia PA,