Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
Location: Duarte CA, Oklahoma City OK, Birmingham AL,
Sponsor: Oncotartis, Inc.
Sex: All
Age: 18+
Code: NCT03921879
Phase1, Recruiting
Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication
for
Medication Adherence, Hypertension, Habits
Location: Los Angeles CA
Sponsor: Chad Stecher@asu.edu
Sex: All
Age: 18+
Code: NCT06876233
Recruiting
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
for
Ulcerative Colitis (UC)
Location: Montreal, Scottsdale AZ, Palo Alto CA, Lubbock TX,
Sponsor: Xencor, Inc.
Sex: All
Age: 18 - 70+
Code: NCT06619990
Phase1, Phase2, Recruiting
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Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation
for
Thyroid Gland Follicular Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06440850
Phase2, Recruiting
Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age
for
Pneumococcal Immunization, Healthy Volunteers
Location: Huntington Park CA, Los Angeles CA, Ogden UT,
Sponsor: Sanofi
Sex: All
Age: 0
Code: NCT07348692
Phase3, Recruiting
Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma
for
High Grade B-Cell Non-Hodgkin's Lymphoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT05801913
Phase1, Recruiting
A Study of LY4005130 in Adult Participants With Non-Segmental Vitiligo
for
Vitiligo, Non-Segmental Vitiligo (NSV)
Location: Northridge CA, Santa Clarita CA, Oxnard CA, Phoenix AZ,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18 - 70+
Code: NCT07533019
Phase2, Recruiting
CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer
for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Duarte CA
Sponsor: Osel, Inc.
Sex: All
Age: 18+
Code: NCT06399419
Phase1, Recruiting
Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma
for
Mantle Cell Lymphoma
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06572618
Phase2, Recruiting
Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules
for
Thyroid Gland Carcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT05229341
Recruiting
Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
for
Psoriatic Arthritis
Location: Riverside CA, Tujunga CA, Thousand Oaks CA, Sun City AZ,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18 - 70+
Code: NCT07486960
Phase2, Recruiting
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)
for
Myelodysplastic Syndromes, Cytopenia
Location: Duarte CA, Houston TX, Hot Springs AR, Memphis TN,
Sponsor: Takeda
Sex: All
Age: 18+
Code: NCT04419649
Phase2, Recruiting
Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma
for
Relapsed Classic Hodgkin Lymphoma
Location: Duarte CA, Chicago IL, Nashville TN, Hackensack NJ,
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT04561206
Phase2, Recruiting
Spatiotemporal Stereotactic Body Radiation Therapy for the Treatment of Patients With Polymetastatic Solid Tumors
for
Metastatic Malignant Solid Neoplasm
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT05733949
Early_phase1, Recruiting
Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma
for
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified,
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT07365306
Phase2, Recruiting
Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV
for
Hepatitis C
Location: Los Angeles CA, Aurora CO, Houston TX, Chicago IL,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Sex: Female
Age: 16 - 45
Code: NCT07040319
Phase1, Phase2, Recruiting
Study of the Safety and Efficacy of STI-6129 in Patients With Relapsed or Refractory Systemic AL Amyloidosis
for
Light Chain (AL) Amyloidosis
Location: Duarte CA, Milwaukee WI, Detroit MI, Boston MA
Sponsor: Sorrento Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT04316442
Phase1, Phase2, Recruiting
A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies
for
Solid Tumors, Hematologic Malignancies
Location: Duarte CA, La Jolla CA, Omaha NE, Houston TX,