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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for
Low-grade NMIBC, FGFR Gene Amplification, FGFR Gene Alterations,
Location: Murrieta CA, San Diego CA, Rancho Mirage CA,
Sponsor: Tyra Biosciences, Inc

Sex: All

Age: 18+

Code: NCT06995677

Phase2, Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

for
Alzheimer Disease
Location: Anaheim CA, Pomona CA, Las Vegas NV, Scottsdale AZ,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 55 - 70+

Code: NCT07011732

Phase3, Recruiting

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

for
AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL),
Location: Duarte CA, Palo Alto CA, Portland OR, Seattle WA,
Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All

Age: 18 - 66

Code: NCT06859424

Phase2, Recruiting

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for
Systemic Lupus Erythematosus
Location: Los Angeles CA, Phoenix AZ, Salt Lake City UT,
Sponsor: AstraZeneca

Sex: All

Age: 5 - 17

Code: NCT05835310

Phase3, Recruiting

Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers

for
Uric Acid Stones
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70+

Code: NCT06335537

Phase1, Recruiting

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Green Tea and Quercetin in Combination With Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Patients

for
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Location: Los Angeles CA
Sponsor: Charles Drew University of Medicine and Science

Sex: Male

Age: 18+

Code: NCT06615752

Phase1, Phase2, Recruiting

Telehealth vs In-Person Evaluation of Addiction Treatment After Visiting the Emergency Department

for
Opioid Use Disorder
Location: Sylmar CA, El Centro CA, Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06961058

Recruiting

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

for
Lumbar Spinal Stenosis, Cardiac Amyloidosis,
Location: Beverly Hills CA, Cleveland OH, New York NY, Boston MA
Sponsor: Columbia University

Sex: All

Age: 50+

Code: NCT06034405

Recruiting

Strain-Counterstrain Treatment of Piriformis Pain

for
Low Back Pain, Mechanical, Piriformis Syndrome,
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: All

Age: 18 - 65

Code: NCT05023005

Recruiting

Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer

for
TNBC, TNBC - Triple-Negative Breast Cancer,
Location: Torrance CA, Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT07017673

Phase2, Recruiting

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

for
HR+ Breast Cancer, Triple Negative Breast Cancer (TNBC),
Location: Duarte CA, La Jolla CA, Las Vegas NV,
Sponsor: NiKang Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07029399

Phase1, Recruiting

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for
Cardiovascular Disease and Lipoprotein(a)
Location: Irvine CA, Huntington Beach CA, Long Beach CA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07517263

Phase3, Recruiting

Telemedicine to Support Living Kidney Donor Candidates

for
Healthy, Living Kidney Donation
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07206069

Recruiting

Diagnosing Epilepsy To EffeCT Change

for
Epilepsy, Epilepsy (Treatment Refractory)
Location: Irvine CA, Phoenix AZ, Palo Alto CA, Billings MT,
Sponsor: Epiminder America, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07110337

Recruiting

A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC

for
PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy,
Location: Los Angeles CA, Murray UT, El Paso TX
Sponsor: Novartis Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT07226986

Phase1, Phase2, Recruiting

A Study of Efimosfermin Alfa in Adults With Hepatic Impairment

for
Non-alcoholic Fatty Liver Disease
Location: Rialto CA, San Antonio TX, Tampa FL
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 70

Code: NCT07358546

Phase1, Recruiting

My Life and My Experiences Project

for
Stress and Memory in Adolescence
Location: Irvine CA
Sponsor: University of California, Irvine

Sex: All

Age: 12 - 18

Code: NCT06821178

Recruiting

Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

for
Lung Cancer, Lung Metastases
Location: Duarte CA, Aurora CO, Houston TX, Rochester MN,
Sponsor: Vergent Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT07499674

Phase3, Recruiting

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

for
Castration-Resistant Prostatic Cancer, Metastasis
Location: Orange CA, Los Angeles CA, San Francisco CA, Seattle WA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06863272

Phase1, Phase2, Recruiting

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Location: Los Angeles CA, San Diego CA, Palo Alto CA, Tucson AZ,
Sponsor: Intellia Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06128629

Phase3, Recruiting