Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC
Location: Lynwood CA, Gresham OR, Prosper TX, Rosharon TX,
Sponsor: Bausch Health Americas, Inc.
Sex: All
Age: 6 - 12
Code: NCT07285785
Recruiting
This Study is to Evaluate Whether Receiving Education and Glucose Monitoring With the CGM Device Will Improve Patient-reported Outcomes by Improving Patient's Satisfaction and Quality of Life (QOL) With Glucose Monitoring Device
for
Diabetes Mellitus
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center
Sex: All
Age: 18+
Code: NCT06965803
Recruiting
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A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors
for
Solid Tumours
Location: Orange CA, Los Angeles CA, West Valley City UT,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18+
Code: NCT07160725
Phase1, Phase2, Recruiting
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
for
Intracerebral Hemorrhage
Location: Orange CA, Downey CA, Riverside CA, Baldwin Park CA,
Sponsor: Joseph Broderick, MD
Sex: All
Age: 18 - 70+
Code: NCT07227246
Phase3, Recruiting
A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression
for
Knee Osteoarthritis, Depression
Location: Los Angeles CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 50 - 70+
Code: NCT06906939
Early_phase1, Recruiting
A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.
for
PROC, Platinum Resistant Ovarian Cancer, Endometrial Cancer
Location: Los Angeles CA, Salt Lake City UT, Dallas TX,
Sponsor: Whitehawk Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT07470853
Phase1, Recruiting
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
for
Untreated, Unresectable, or Metastatic Colorectal Cancer
Location: Orange CA, Los Angeles CA, Vancouver WA, San Antonio TX,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18+
Code: NCT07221357
Phase2, Phase3, Recruiting
IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)
for
Relapsed/Refractory Primary Central Nervous System Lymphoma
Location: Orange CA, Fullerton CA, Phoenix AZ, Scottsdale AZ,
Sponsor: Ono Pharmaceutical Co., Ltd.
Sex: All
Age: 18+
Code: NCT07104032
Phase3, Recruiting
Advanced Imaging Techniques for Evaluating the Tumor Immune Microenvironment in Glioblastoma Patients
for
Glioblastoma
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center
Sex: All
Age: 18+
Code: NCT07461948
Phase3, Recruiting
A Clinical Trial Comparing 2x/Day for 30-minutes Use of the Emanate Perio PODS Post-SRP to a Control Group Post-SRP.
for
Periodontitis (Stage 3)
Location: Fullerton CA, La Vista NE, Spring TX, Houston TX,
Sponsor: McGuire Institute
Sex: All
Age: 30 - 70+
Code: NCT06914596
Recruiting
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
for
Non-small Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic,
Location: Fullerton CA, Vista CA, Encinitas CA, San Diego CA,
Sponsor: Pfizer
Sex: All
Age: 18+
Code: NCT07144280
Phase3, Recruiting
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
for
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma,
Location: Orange CA, Los Angeles CA, Eugene OR, Portland OR,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18+
Code: NCT07221149
Phase2, Phase3, Recruiting
A Phase 1/2, First-in-Human Study On ODM-212 In Subjects With Selected Advanced Solid Tumours
for
Solid Tumours
Location: Orange CA, Los Angeles CA, Houston TX, St Louis MO,
Sponsor: Orion Corporation, Orion Pharma
Sex: All
Age: 18+
Code: NCT06725758
Phase1, Phase2, Recruiting
A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours)
for
Advanced Relapsed or Refractory Germ Cell Tumours,
Location: Los Angeles CA, Houston TX
Sponsor: Boehringer Ingelheim
Sex: All
Age: 18+
Code: NCT07306559
Phase1, Recruiting
Virtual Reality (VR) for Interventional Radiology (IR) Procedures
for
Pain, Procedural Anxiety
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles
Sex: All
Age: 8+
Code: NCT07427862
Recruiting
A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma
for
Diffuse Large B-cell Lymphoma (DLBCL)
Location: Orange CA, Los Angeles CA, Scottsdale AZ, Sacramento CA,
Sponsor: Regeneron Pharmaceuticals
Sex: All
Age: 18+
Code: NCT06091865
Phase3, Recruiting
Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)
for
Ewing Sarcoma
Location: Los Angeles CA, Houston TX, Philadelphia PA,