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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection

for
Hepatitis B Virus Infection
Location: Lake Forest CA, Huntington Beach CA, Long Beach CA,
Sponsor: GigaGen, Inc.

Sex: All

Age: 18+

Code: NCT07024641

Phase1, Recruiting

Lucid Registry Study

for
Barrett Esophagus, Esophageal Adenocarcinoma,
Location: Lake Forest CA
Sponsor: Lucid Diagnostics, Inc.

Sex: All

Age: 12+

Code: NCT05965999

Recruiting

Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

for
Neovascular Age-Related Macular Degeneration (nAMD)
Location: Fullerton CA, Sun City AZ, Campbell CA, Scottsdale AZ,
Sponsor: 4D Molecular Therapeutics

Sex: All

Age: 50+

Code: NCT07064759

Phase3, Recruiting

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for
Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
Location: Long Beach CA, Los Angeles CA, San Diego CA, Fresno CA,
Sponsor: Duke University

Sex: All

Age: 70+

Code: NCT04262206

Recruiting

Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

for
Atopic Dermatitis
Location: Santa Ana CA, Fountain Valley CA, Los Angeles CA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06947993

Phase2, Recruiting

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A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

for
Obesity, Overweight, Chronic Weight Management,
Location: Fountain Valley CA, Rolling Hills Estates CA,
Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07654374

Phase3, Recruiting

Dynamic Cervical Change: Prediction of Preterm Labor in Symptomatic Patients

for
Dynamic Cervical Change in Preterm Labor Patients
Location: Laguna Hills CA, Long Beach CA
Sponsor: Memorial Health Services Research Council

Sex: Female

Age: 18 - 45

Code: NCT00298480

Recruiting

Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

for
Delirium, Neurocognitive Disorders, Mild Cognitive Impairment,
Location: Orange CA, Salt Lake City UT, Madison WI, Ann Arbor MI,
Sponsor: University of Michigan

Sex: All

Age: 70+

Code: NCT05929703

Recruiting

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for
Lymphoma, Large B-Cell, Diffuse
Location: Duarte CA, Burbank CA, Goodyear AZ, Glendale AZ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06890884

Phase2, Recruiting

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Non Small Cell Lung Cancer,
Location: Los Angeles CA, Salt Lake City UT, Seattle WA,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07020221

Phase1, Phase2, Recruiting

Prostate Cancer Postoperative Stereotactic Body Radiotherapy With Adaptive Technology for Minimizing Toxicity

for
Prostate Cancer (CRPC)
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male

Age: 18+

Code: NCT07077239

Recruiting

Clarifying the Optimal Application of SLT Therapy Trial

for
Glaucoma and Ocular Hypertension
Location: Laguna Hills CA, Pasadena CA, San Francisco CA,
Sponsor: University of Pittsburgh

Sex: All

Age: 18+

Code: NCT04967989

Phase3, Recruiting

Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States

for
No Condition,
Location: Downey CA, Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07110688

Recruiting
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A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Salt Lake City UT, Denver CO,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06892522

Phase1, Phase2, Recruiting

Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

for
Neurotrophic Keratopathy
Location: Laguna Hills CA, Loma Linda CA, Medford OR, Longmont CO,
Sponsor: ReGenTree, LLC

Sex: All

Age: 18+

Code: NCT05555589

Phase3, Recruiting

CGM Academy for Youth With Type 1 Diabetes

for
Type1 Diabetes
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles

Sex: All

Age: 8 - 18

Code: NCT06408207

Recruiting

A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment

for
Hepatic Impairment
Location: Lake Forest CA, San Dimas CA, San Antonio TX,
Sponsor: Insmed Incorporated

Sex: All

Age: 18 - 70

Code: NCT07643155

Phase1, Recruiting

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for
Transthyretin Amyloidosis With Cardiomyopathy
Location: Laguna Hills CA, La Jolla CA, Stanford CA,
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07052903

Phase3, Recruiting

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

for
Major Depressive Disorder
Location: Bellflower CA, Sherman Oaks CA, La Jolla CA,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT07076407

Phase3, Recruiting

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: Los Angeles CA, La Jolla CA, Portland OR, Seattle WA,
Sponsor: Regeneron Pharmaceuticals

Sex: Female

Age: 18+

Code: NCT06787612

Phase2, Recruiting