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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

for
Sickle Cell Disease
Location: Los Angeles CA, Palo Alto CA, St Louis MO, Columbus OH,
Sponsor: Kamau Therapeutics

Sex: All

Age: 12 - 50

Code: NCT04819841

Phase1, Phase2, Recruiting
Active & Responsive

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

for
Alagille Syndrome
Location: Los Angeles CA, San Francisco CA, El Paso TX, Dallas TX,
Sponsor: Ipsen

Sex: All

Age: 0+

Code: NCT06850038

Recruiting
Active & Responsive

Very Brief Exposure: Development of a Novel Exposure Modality for Social Anxiety Disorder in Transition-Age Youth

for
Social Anxiety Disorder
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles

Sex: All

Age: 16 - 22

Code: NCT06526260

Recruiting
Active & Responsive

ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

for
X-linked Retinoschisis
Location: Los Angeles CA, Phoenix AZ, San Francisco CA,
Sponsor: Atsena Therapeutics Inc.

Sex: All

Age: 5+

Code: NCT05878860

Phase3, Recruiting
Active & Responsive

A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

for
Cytomegalovirus Prophylaxis
Location: Los Angeles CA, Palo Alto CA, San Francisco CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 17

Code: NCT07199465

Phase1, Recruiting

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Active & Responsive

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for
Single Ventricle Heart Disease
Location: Los Angeles CA, San Diego CA, Phoenix AZ,
Sponsor: Mezzion Pharma Co. Ltd

Sex: All

Age: 12 - 18

Code: NCT05918211

Phase3, Recruiting
Active & Responsive

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for
Lung Cancer Diagnosis
Location: Los Angeles CA, Houston TX, Reno NV, Portland OR,
Sponsor: Freenome Holdings Inc.

Sex: All

Age: 50+

Code: NCT06122077

Recruiting
Active & ResponsiveNew

Study of GS-0415 and How It Works in People With HIV

for
HIV -1 Infection
Location: Los Angeles CA, Las Vegas NV, Indianapolis IN,
Sponsor: Gilead Sciences

Sex: All

Age: 18 - 65

Code: NCT07719491

Phase1, Recruiting
Active & Responsive

ALS/MND Natural History Study Data Repository

for
ALS, PLS, MND (Motor Neurone DIsease), Kennedy Disease,
Location: Los Angeles CA, Loma Linda CA, Portland OR,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT05966038

Recruiting
Active & Responsive

A Gaucher Disease Gene Therapy Trial With FLT201

for
Gaucher Disease Type 1
Location: Los Angeles CA, San Francisco CA, Aurora CO, Dallas TX,
Sponsor: Spur Therapeutics

Sex: All

Age: 18+

Code: NCT07223944

Phase3, Recruiting
Active & Responsive

Buprenorphine Implementation at Syringe Service Programs to Reduce Overdoses

for
Opioid Use Disorder, Opioid Use Disorder, Severe,
Location: Los Angeles CA, Grants Pass OR, Roswell NM,
Sponsor: Montefiore Medical Center

Sex: All

Age: 18+

Code: NCT07631598

Recruiting
Active & ResponsiveNew

A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers

for
Healthy Participants
Location: Glendale CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 55

Code: NCT06951880

Phase1, Recruiting
Active & ResponsiveNew

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)

for
Diabetic Retinopathy, Macular Edema
Location: Glendale CA, Denver CO, Austin TX, Johnson City TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07705555

Phase3, Recruiting
Active & Responsive

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

for
Healthy Participants, Obesity
Location: Glendale CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 65

Code: NCT07511205

Phase1, Recruiting
Active & Responsive

A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockade

for
Fentanyl Overdose, Fentanyl Poisoning
Location: Glendale CA
Sponsor: Clear Scientific, Inc.

Sex: All

Age: 18 - 55

Code: NCT07459166

Phase2, Recruiting
Active & Responsive

A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine

for
Methamphetamine Intoxication, Methamphetamine Disorders,
Location: Glendale CA
Sponsor: Clear Scientific, Inc.

Sex: All

Age: 18 - 55

Code: NCT06721494

Phase2, Recruiting
Active & Responsive

A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity

for
Obesity, Overweight
Location: Glendale CA, Baltimore MD
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18 - 55

Code: NCT07566390

Phase1, Recruiting
Active & Responsive

VTP-1000 in Adults With Celiac Disease

for
Celiac Disease
Location: Los Angeles CA, West Jordan UT, Colorado Springs CO,
Sponsor: Barinthus Biotherapeutics

Sex: All

Age: 18 - 70

Code: NCT06310291

Early_phase1, Recruiting
Active & Responsive

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

for
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Location: Los Angeles CA, Denver CO, Seattle WA, Vancouver,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07266831

Phase2, Phase3, Recruiting
Active & Responsive

A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed

for
HIV Infections
Location: Los Angeles CA, San Diego CA, Bakersfield CA,
Sponsor: ViiV Healthcare

Sex: All

Age: 12+

Code: NCT07650916

Phase3, Recruiting