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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07619599

Phase1, Recruiting
Active & Responsive

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for
Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,
Location: Duarte CA, Atlanta GA, Boston MA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT07020533

Phase1, Recruiting
Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Duarte CA, Beverly Hills CA, Los Angeles CA,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase3, Recruiting
Active & Responsive

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

for
Malignant Brain Neoplasm, Recurrent Malignant Brain Neoplasm,
Location: Duarte CA, Los Angeles CA, Ann Arbor MI
Sponsor: City of Hope Medical Center

Sex: All

Age: 4 - 25

Code: NCT04510051

Phase1, Recruiting
Active & Responsive

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

for
Obstructive Sleep Apnea
Location: Rolling Hills Estates CA, Northridge CA, Bellevue WA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07226765

Phase3, Recruiting

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Active & Responsive

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for
Pulmonary Hypertension, Interstitial Lung Disease (ILD)
Location: Riverside CA, Phoenix AZ, Reno NV, Salt Lake City UT,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT06911632

Recruiting
Active & Responsive

A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for
Solid Tumor
Location: Duarte CA, La Jolla CA, Palo Alto CA,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT06384807

Phase1, Phase2, Recruiting
Active & Responsive

Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)

for
Endometriosis
Location: Burbank CA, Chandler AZ, Forest Hill IN, Cincinnati OH,
Sponsor: Aspira Women's Health

Sex: Female

Age: 14 - 50

Code: NCT05245695

Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis

for
Atopic Dermatitis, Atopic Dermatitis Eczema, Eczema
Location: Los Angeles CA, Lancaster CA, Portland OR, Burien WA,
Sponsor: Inmagene LLC

Sex: All

Age: 18 - 70+

Code: NCT07037901

Phase2, Recruiting
Active & Responsive

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Location: Los Angeles CA, Rancho Mirage CA, Las Vegas NV,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07198074

Phase3, Recruiting
Active & Responsive

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

for
Inherited Retinal Degeneration, Retinitis Pigmentosa
Location: Los Angeles CA, San Francisco CA, Salt Lake City UT,
Sponsor: Jaeb Center for Health Research

Sex: All

Age: 4+

Code: NCT05589714

Recruiting
Active & Responsive

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for
Stroke, Stroke, Acute, Stroke, Ischemic
Location: Los Angeles CA, Redwood City CA, San Francisco CA,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT05338697

Recruiting
Active & Responsive

Examination of Nociscan Impact on Low Back Pain Surgical Outcomes

for
Low Back Pain
Location: Los Angeles CA, Beverly Hills CA, La Jolla CA,
Sponsor: Aclarion

Sex: All

Age: 18 - 70

Code: NCT06661850

Recruiting
Active & Responsive

The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for
Intracranial Aneurysm
Location: Los Angeles CA, Salt Lake City UT, Englewood CO,
Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All

Age: 18 - 70+

Code: NCT02998229

Recruiting
Active & Responsive

Multi-Site Trial of Tirzepatide for Smoking Cessation

for
Smoking Cessation, Smoking Behaviors
Location: Los Angeles CA, Aurora CO, Chicago IL, New Haven CT
Sponsor: University of Southern California

Sex: All

Age: 21 - 65

Code: NCT07602699

Phase2, Recruiting
Active & Responsive

Tirzepatide for Alcohol Use Disorder

for
Alcohol Use Disorder, Obesity and Overweight, Alcohol
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 21 - 65

Code: NCT06994338

Phase2, Recruiting
Active & Responsive

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for
Parkinson Disease
Location: Los Angeles CA, La Jolla CA, Las Vegas NV, Sun City AZ,
Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All

Age: 30+

Code: NCT04477785

Recruiting
Active & Responsive

Assessment of CCM in HF With Higher Ejection Fraction

for
Heart Failure, Heart Failure With Preserved Ejection Fraction,
Location: Los Angeles CA, Northridge CA, La Jolla CA, Phoenix AZ,
Sponsor: Impulse Dynamics

Sex: All

Age: 18+

Code: NCT05064709

Recruiting
Active & Responsive

Hyperemesis Gravidarum Risk Reduction With Metformin

for
Hyperemesis Gravidarum
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: Female

Age: 18 - 49

Code: NCT07129473

Phase1, Phase2, Recruiting
Active & Responsive

A Study of PHST001 in Advanced Solid Tumors

for
Advanced Solid Tumors, Ovarian Cancer, Endometrial Cancer,
Location: Los Angeles CA, Beverly Hills CA, Palo Alto CA,
Sponsor: Pheast Therapeutics

Sex: All

Age: 18+

Code: NCT06840886

Phase1, Recruiting