Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
Active & Responsive
A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients
for
Breast Cancer Screening, Artificial Intelligence (AI)
Location: Los Angeles CA, San Diego CA, Seattle WA, Madison WI,
Sponsor: Jonsson Comprehensive Cancer Center
Sex: All
Age: 18+
Code: NCT06934239
Recruiting
Active & Responsive
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
for
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF),
Location: Los Angeles CA, San Diego CA, Seattle WA, Milwaukee WI,
Sponsor: Regeneron Pharmaceuticals
Sex: All
Age: 0+
Code: NCT05788536
Phase1, Phase2, Recruiting
Active & Responsive
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Location: Los Angeles CA, Sacramento CA, Salt Lake City UT,
Sponsor: Abbott Medical Devices
Sex: All
Age: 22 - 70
Code: NCT06423430
Recruiting
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Active & Responsive
Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
for
Advanced Solid Tumors
Location: Los Angeles CA, San Francisco CA, Aurora CO,
Sponsor: ModernaTX, Inc.
Sex: All
Age: 12+
Code: NCT05533697
Phase1, Phase2, Recruiting
Active & Responsive
Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma
for
Melanoma, Unresectable Melanoma
Location: Los Angeles CA, New York NY, Boston MA
Sponsor: NYU Langone Health
Sex: All
Age: 18 - 70+
Code: NCT05428007
Phase2, Recruiting
Active & Responsive
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
for
Major Depressive Disorder
Location: Redlands CA, Huntsville AL, Glendale CA,
Sponsor: Neurocrine Biosciences
Sex: All
Age: 18+
Code: NCT06911112
Phase3, Recruiting
Active & Responsive
Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression
for
Depression in Adolescence
Location: Los Angeles CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 14 - 21
Code: NCT05329441
Recruiting
Active & Responsive
A Study of SGT-212 Gene Therapy in Friedreich's Ataxia
for
Friedreich's Ataxia (FA)
Location: Los Angeles CA, Columbus OH, Philadelphia PA
Sponsor: Solid Biosciences Inc.
Sex: All
Age: 18 - 40
Code: NCT07180355
Phase1, Recruiting
Active & Responsive
Inter-Brain Synchrony in Schizophrenia
for
Schizophrenia Disorder
Location: Los Angeles CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 18 - 65
Code: NCT07177261
Recruiting
Active & Responsive
Evaluating tDCS Brain-stimulation in Depression Using MRI
for
Major Depressive Disorder
Location: Los Angeles CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 20 - 55
Code: NCT05598034
Recruiting
Active & Responsive
Unconscious Reduction of Fear Through Decoded Neuro-Reinforcement
for
Phobia
Location: Los Angeles CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 18 - 65
Code: NCT06420557
Recruiting
Active & Responsive
Training Reward Responsiveness Through Virtual Reality
for
Positive Affect, Depression
Location: Los Angeles CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 18+
Code: NCT07219875
Phase2, Recruiting
Active & Responsive
Reward Processing and Exposure Therapy for Social Anxiety Disorder
for
Social Anxiety Disorder (Social Phobia),
Location: Los Angeles CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 18 - 60
Code: NCT06776991
Recruiting
Active & Responsive
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
for
Long COVID, Sars-CoV-2 Infection, Coronavirus Infections,
Location: Los Angeles CA, San Francisco CA, Tucson AZ, Aurora CO,
Sponsor: Wes Ely
Sex: All
Age: 18+
Code: NCT06631287
Phase3, Recruiting
Active & Responsive
A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).
for
Prevention, Control
Location: Los Angeles CA, Evanston IL, Nashville TN
Sponsor: Vanderbilt University
Sex: All
Age: 12 - 17
Code: NCT06526052
Recruiting
Active & Responsive
American Lung Association (ALA) Lung Health Cohort
for
Lung Diseases
Location: Los Angeles CA, San Francisco CA, Tucson AZ, Denver CO,
Sponsor: Johns Hopkins University
Sex: All
Age: 25 - 35
Code: NCT04543461
Recruiting
Active & Responsive
Examining the Effects of Cytisinicline on Neural Substrates of Cigarette Cue-reactivity
for
Smoking Cessation, Tobacco Use Disorder
Location: Los Angeles CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 18 - 65
Code: NCT06617312
Phase2, Recruiting
Active & Responsive
Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder
for
Methamphetamine-dependence, Methamphetamine Abuse
Location: Los Angeles CA, San Diego CA, Dallas TX, Kansas City KS,