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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for
Frontotemporal Lobar Degeneration (FTLD),
Location: Los Angeles CA, San Diego CA, Las Vegas NV,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04363684

Recruiting
Active & Responsive

FOG-001 in Locally Advanced or Metastatic Solid Tumors

for
Cancer, Colorectal Cancer, Solid Tumor,
Location: Los Angeles CA, Santa Monica CA, Phoenix AZ,
Sponsor: Parabilis Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05919264

Phase1, Phase2, Recruiting
Active & Responsive

Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease

for
Sickle Cell Disease
Location: Los Angeles CA, Oakland CA
Sponsor: Mark Walters, MD

Sex: All

Age: 12 - 35

Code: NCT04774536

Phase1, Phase2, Recruiting
Active & Responsive

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for
Hereditary Hemorrhagic Telangiectasia,
Location: Los Angeles CA, San Francisco CA, Salt Lake City UT,
Sponsor: Cure HHT

Sex: All

Age: 0+

Code: NCT06259292

Recruiting
Active & Responsive

AACR Adaptive Biomarker-Driven Organ Preservation Trial in Gastroesophageal Adenocarcinomas

for
Gastroesophageal Adenocarcinoma
Location: Los Angeles CA, Toronto, New Haven CT
Sponsor: American Association for Cancer Research

Sex: All

Age: 18+

Code: NCT07290985

Phase2, Recruiting

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Active & Responsive

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

for
AML With Gene Mutations
Location: Los Angeles CA, San Francisco CA, Portland OR,
Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All

Age: 18+

Code: NCT06366789

Phase1, Recruiting
Active & Responsive

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

for
LAMA2-MD \(Merosin Deficient Congenital Muscular Dystrophy, MDC1A\),
Location: Los Angeles CA, Stanford CA, Dallas TX, Saint Paul MN,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 0 - 5

Code: NCT06503367

Recruiting
Active & Responsive

DMCRN-02-001: Assessing Pediatric Endpoints in DM1

for
Congenital Myotonic Dystrophy, CDM
Location: Los Angeles CA, Fairway KS, Rochester NY, Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 0 - 4

Code: NCT05224778

Recruiting
Active & Responsive

Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

for
Systemic Lupus Erythematosus
Location: Los Angeles CA, San Diego CA, Oklahoma City OK,
Sponsor: NYU Langone Health

Sex: All

Age: 55+

Code: NCT05799378

Phase3, Recruiting
Active & Responsive

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

for
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma,
Location: Los Angeles CA, Aurora CO, Houston TX, Madison WI,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06428409

Phase1, Phase2, Recruiting
Active & Responsive

A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)

for
PIK3CA-Related Overgrowth Spectrum (PROS),
Location: Los Angeles CA, Phoenix AZ, Palo Alto CA,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 2+

Code: NCT06789913

Phase2, Recruiting
Active & Responsive

Motivation for IV Alcohol Self-Administration in Humans

for
Alcohol Use Disorder
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 21 - 65

Code: NCT06494891

Phase2, Recruiting
Active & Responsive

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

for
Post-Concussion Syndrome, Concussion, Brain,
Location: Westwood, Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18 - 65

Code: NCT06073886

Phase2, Recruiting
Active & Responsive

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: Los Angeles CA, La Jolla CA, Phoenix AZ, Stanford CA,
Sponsor: Bicara Therapeutics

Sex: All

Age: 18+

Code: NCT06788990

Phase2, Phase3, Recruiting
Active & ResponsiveNew

Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation

for
Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation,
Location: Los Angeles CA, Minneapolis MN, Chicago IL, Boston MA
Sponsor: Institut de Recherches Internationales Servier (I.R.I.S.)

Sex: All

Age: 12 - 17

Code: NCT07286292

Phase2, Recruiting
Active & Responsive

Impact of Prebiotics in Ulcerative Colitis

for
Crohn Disease, Ulcerative Colitis
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18 - 70+

Code: NCT06495658

Recruiting
Active & Responsive

Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

for
Breast Neoplasms, Breast Cancer
Location: Santa Monica CA, Tigard OR, Billings MT, Dallas TX,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06797635

Phase2, Recruiting
Active & Responsive

BBD Longitudinal Study of Osteogenesis Imperfecta

for
Osteogenesis Imperfecta
Location: Los Angeles CA, Phoenix AZ, Portland OR, Omaha NE,
Sponsor: Baylor College of Medicine

Sex: All

Age: 0+

Code: NCT02432625

Recruiting
Active & Responsive

Diagnostic Performance Study of the EMVision Emu™ Brain Scanner in the Detection of Intracranial Hemorrhage in Suspected Stroke Patients

for
Stroke, Hemorrhagic Stroke
Location: Los Angeles CA, Houston TX, Jacksonville FL,
Sponsor: EMVision Medical Devices Ltd

Sex: All

Age: 22+

Code: NCT06999122

Recruiting
Active & Responsive

Human Laboratory Study of Apremilast for Alcohol Use Disorder

for
Alcohol Use Disorder, Alcohol Misuse
Location: Los Angeles CA, Aurora CO, Charlottesville VA
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All

Age: 21+

Code: NCT07325266

Phase2, Recruiting