Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
for
Overweight, Obesity
Location: Irvine CA, Tustin CA, Santa Ana CA,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT07392190
Phase3, Recruiting
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
for
Metastatic Colorectal Cancer (CRC)
Location: Irvine CA, Fountain Valley CA, Orange CA,
Sponsor: Summit Therapeutics
Sex: All
Age: 18+
Code: NCT07228832
Phase3, Recruiting
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
for
Metastatic Clear Cell Renal Cell Carcinoma,
Location: Irvine CA, Duarte CA, Los Angeles CA, La Jolla CA,
Sponsor: Arcus Biosciences, Inc.
Sex: All
Age: 18+
Code: NCT07011719
Phase3, Recruiting
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
for
Alzheimer Disease, Dementia, Plaque, Amyloid
Location: Irvine CA, Santa Ana CA, Huntington Beach CA,
Sponsor: Eli Lilly and Company
Sex: All
Age: 55+
Code: NCT07602582
Phase3, Recruiting
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
for
Lichen Planopilaris
Location: Irvine CA, Phoenix AZ, Scottsdale AZ, Oakland CA,
Sponsor: Priovant Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT07532603
Phase2, Phase3, Recruiting
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A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
for
Early Alzheimer's Disease
Location: Irvine CA, Santa Ana CA, Long Beach CA, Los Angeles CA,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 50 - 70+
Code: NCT07033494
Phase2, Recruiting
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
for
Lewy Body Dementia Psychosis
Location: Irvine CA, Aurora CO, Kirkland WA, San Antonio TX,
Sponsor: ACADIA Pharmaceuticals Inc.
Sex: All
Age: 55 - 70+
Code: NCT07029581
Phase2, Recruiting
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
for
Alzheimer's Disease
Location: Irvine CA, Fullerton CA, Los Angeles CA, Palo Alto CA,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 60 - 70+
Code: NCT06976203
Phase3, Recruiting
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)
for
Polymyositis, Dermatomyositis
Location: Irvine CA, El Paso TX, Aurora CO, Colleyville TX,
Sponsor: AstraZeneca
Sex: All
Age: 18 - 70+
Code: NCT06455449
Phase3, Recruiting
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
for
Migraine
Location: Irvine CA, Mission Viejo CA, Riverside CA,
Sponsor: Kallyope Inc.
Sex: All
Age: 18 - 70+
Code: NCT07645924
Phase3, Recruiting
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
for
Acute Migraine
Location: Irvine CA, Mission Viejo CA, Riverside CA,
Sponsor: Kallyope Inc.
Sex: All
Age: 18+
Code: NCT07674654
Phase3, Recruiting
TTVR STRONG Under Coverage With Evidence Development (CED) Study
for
Tricuspid Regurgitation
Location: Irvine CA
Sponsor: Edwards Lifesciences
Sex: All
Age: 65+
Code: NCT06833476
Recruiting
Multi-Institutional Registry for Prostate Cancer Radiosurgery
for
Prostate Cancer Early Risk Treated by Radiosurgery,
Location: Tustin CA, Newport Beach CA, San Diego CA, Henderson NV,
Sponsor: RPCR, Inc.
Sex: Male
Age: 18 - 70+
Code: NCT01226004
Recruiting
Acoustic and Electrical Stimulation for the Treatment of Tinnitus
for
Tinnitus
Location: Irvine CA
Sponsor: University of California, Irvine
Sex: All
Age: 18+
Code: NCT03511807
Recruiting
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
for
Metastatic Castration Sensitive Prostate Cancer (mCSPC),
Location: Irvine CA, Laguna Hills CA, Torrance CA, Alhambra CA,
Sponsor: Pfizer
Sex: Male
Age: 18+
Code: NCT07028853
Phase3, Recruiting
Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)
for
Fragile X Syndrome
Location: Irvine CA, Orange CA, Phoenix AZ, Sacramento CA,
Sponsor: Mirum Pharmaceuticals, Inc.
Sex: Male
Age: 13 - 45
Code: NCT07209462
Phase2, Recruiting
New
Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)
for
Lung Cancer Screening, Lung Neoplasms, Smoking ( Cigarette),
Location: Irvine CA, Newport Beach CA, Tustin CA, Santa Ana CA,
Sponsor: University of California, Irvine
Sex: All
Age: 50 - 70+
Code: NCT07711691
Recruiting
New
Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma