Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
for
Neutropenia
Location: Irvine CA, Los Angeles CA, La Jolla CA, Phoenix AZ,
Sponsor: X4 Pharmaceuticals
Sex: All
Age: 12+
Code: NCT06056297
Phase3, Recruiting
A Global Prospective Observational Registry of Patients With Pompe Disease
for
Pompe Disease
Location: Irvine CA, Salt Lake City UT, Little Rock AR,
Sponsor: Amicus Therapeutics
Sex: All
Age: 0+
Code: NCT06121011
Recruiting
Regeneron AA Multicenter (Dupilumab)
for
Alopecia Areata
Location: Irvine CA, Rochester NY, New York NY
Sponsor: Emma Guttman
Sex: All
Age: 18+
Code: NCT05551793
Phase2, Recruiting
Early Prostate Cancer: Predicting Treatment Response
for
Prostate Cancer
Location: Irvine CA, Long Beach CA, Los Angeles CA,
Sponsor: University of California, Irvine
Sex: Male
Age: 18 - 70+
Code: NCT03770351
Recruiting
A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum
for
Pyoderma Gangrenosum
Location: Irvine CA, Phoenix AZ, Murray UT, Meridian ID,
Sponsor: LEO Pharma
Sex: All
Age: 18+
Code: NCT06624670
Phase3, Recruiting
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A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer
for
Nasopharyngeal Cancer Recurrent
Location: Irvine CA, San Francisco CA, Little Rock AR,
Sponsor: Coherus Oncology, Inc.
Sex: All
Age: 12+
Code: NCT06457503
Recruiting
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo
for
NonSegmental Vitiligo
Location: Irvine CA, Pomona CA, Inglewood CA, Los Angeles CA,
Sponsor: Incyte Corporation
Sex: All
Age: 2 - 11
Code: NCT06548360
Phase3, Recruiting
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
for
Non-small Cell Lung Cancer,
Location: Newport Beach CA, Duarte CA, Santa Monica CA,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT05877599
Phase1, Recruiting
VALOR: Vaginal Atrophy & Long-term Observation of Recovery
for
Atrophic Vaginitis, Vaginal Atrophy,
Location: Newport Beach CA, Burbank CA, Dallas TX, Birmingham AL,
Sponsor: Stratpharma AG
Sex: Female
Age: 18+
Code: NCT05953090
Recruiting
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
for
Asthma
Location: Newport Beach CA, Bakersfield CA, San Jose CA,
Sponsor: AstraZeneca
Sex: All
Age: 18 - 70+
Code: NCT06932263
Phase2, Recruiting
A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.
for
Idiopathic Pulmonary Fibrosis (IPF)
Location: Newport Beach CA, Phoenix AZ, El Paso TX, Champaign IL,
Sponsor: AstraZeneca
Sex: All
Age: 40+
Code: NCT07652658
Phase2, Recruiting
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
for
Asthma
Location: Newport Beach CA, Aurora CO, Rapid City SD,
Sponsor: GlaxoSmithKline
Sex: All
Age: 12+
Code: NCT07456033
Phase3, Recruiting
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
for
Sepsis, Acute Kidney Injury
Location: Newport Beach CA, Kansas City KS, Detroit MI,
Sponsor: AstraZeneca
Sex: All
Age: 18 - 70+
Code: NCT07215702
Phase2, Recruiting
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
for
Pulmonary Disease, Chronic Obstructive
Location: Newport Beach CA, Henderson NV, Las Vegas NV, Reno NV,
Sponsor: GlaxoSmithKline
Sex: All
Age: 40 - 70+
Code: NCT07177339
Phase3, Recruiting
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
for
Non-small Cell Lung Cancer, Colorectal Carcinoma,
Location: Newport Beach CA, Duarte CA, Los Angeles CA,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT06218914
Phase1, Recruiting
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
for
Cardiovascular Disease
Location: Newport Beach CA, Fountain Valley CA, Garden Grove CA,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT07000357
Phase3, Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Newport Beach CA, Norco CA, Los Angeles CA, Phoenix AZ,
Sponsor: AstraZeneca
Sex: All
Age: 40+
Code: NCT07082738
Phase2, Recruiting
A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors
for
Recurrent or Metastatic Solid Tumors
Location: Newport Beach CA, Las Vegas NV, Nashville TN,
Sponsor: Daiichi Sankyo
Sex: All
Age: 18+
Code: NCT07015697
Phase1, Recruiting
Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
for
Advanced Breast Cancer
Location: Newport Beach CA, Fountain Valley CA, Los Angeles CA,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT06380751
Phase3, Recruiting
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Newport Beach CA, Garden Grove CA, Torrance CA,