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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Integrated Cf-miRNA and Exosomal miRNA Signature for Early Detection of Esophageal Squamous Cell Carcinoma

for
ESCC
Location: Monrovia CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07266363

Recruiting

Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for
Coronary Artery Disease,
Location: Loma Linda CA, Thousand Oaks CA, Sacramento CA,
Sponsor: Supira Medical

Sex: All

Age: 18 - 70+

Code: NCT07296744

Recruiting

Individualized AML Treatment

for
Relapsed/Refractory Acute Myeloid Leukemia (AML)
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07613385

Recruiting

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

for
Recurrent Astrocytoma, IDH-Mutant, Grade 3,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06815029

Phase1, Recruiting

Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06498973

Phase1, Recruiting

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Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

for
Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8
Location: Duarte CA, Columbus OH
Sponsor: City of Hope Medical Center

Sex: All

Age: 60+

Code: NCT06139627

Recruiting

Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06054776

Phase2, Recruiting

Quality of Life in Cutaneous Lymphoma Patients Using the Skindex29

for
Cutaneous Lymphoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT04670874

Recruiting

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

for
Advanced Prostate Carcinoma, Metastatic Prostate Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: Male

Age: 60+

Code: NCT05869682

Phase2, Recruiting

Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas

for
Follicular Helper T-Cell Lymphoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07278856

Phase1, Recruiting

Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer

for
Gastric Carcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 40 - 70+

Code: NCT06408220

Recruiting

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

for
PIK3CA Mutations, Advanced Solid Tumors, Adult,
Location: Los Angeles CA, Scottsdale AZ, West Valley City UT,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07383506

Phase1, Recruiting

Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer

for
Castration-Sensitive Prostate Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: Male

Age: 18+

Code: NCT04734730

Phase2, Recruiting

BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL

for
Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Location: Duarte CA, Stanford CA, Seattle WA, Kansas City KS,
Sponsor: PeproMene Bio, Inc.

Sex: All

Age: 18+

Code: NCT05370430

Phase1, Recruiting

Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration

for
Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD
Location: Fullerton CA, Bakersfield CA, Phoenix AZ,
Sponsor: Adverum Biotechnologies, Inc.

Sex: All

Age: 50+

Code: NCT07630649

Phase2, Recruiting

PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy

for
Postpartum Hypertension (PPHT)
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: Female

Age: 18 - 64

Code: NCT06915792

Recruiting

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

for
Hematologic Malignancies
Location: Duarte CA, Goodyear AZ, Scottsdale AZ, Dallas TX,
Sponsor: Sellas Life Sciences Group

Sex: All

Age: 12+

Code: NCT04588922

Phase1, Phase2, Recruiting

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

for
Persistent Corneal Epithelial Defect
Location: Laguna Hills CA, Huntington Beach CA, Redlands CA,
Sponsor: Dompé Farmaceutici S.p.A

Sex: All

Age: 18+

Code: NCT07519902

Phase3, Recruiting

A2-ESO-1 TCR-Engineered T Cells for Relapsed/Refractory Advanced or Metastatic NY-ESO-1 Overexpression Positive Triple Negative Breast Cancer

for
Triple Negative Breast Cancer
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: Female

Age: 18+

Code: NCT05989828

Phase1, Recruiting

Study of Aritinercept in Patients With Generalized Myasthenia Gravis

for
Myasthenia Gravis, Generalized
Location: Pasadena CA, Houston TX, O'Fallon IL, Chicago IL,
Sponsor: Aurinia Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT07596901

Phase1, Phase2, Recruiting