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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors

for
Advanced Cancer, Solid Tumor, Metastatic Cancer
Location: Duarte CA, Omaha NE, Miami FL
Sponsor: Proviva Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06190886

Phase1, Recruiting

Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

for
Locally Advanced Rectal Adenocarcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06834126

Phase1, Recruiting

A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes

for
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: Duarte CA, Kansas City KS, New York NY
Sponsor: GluBio Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06146257

Phase1, Recruiting

Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease

for
Sickle Cell Disease
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 1 - 30

Code: NCT03279094

Phase1, Recruiting

Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study

for
B-Cell Non-Hodgkin Lymphoma, Multiple Myeloma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 60+

Code: NCT06052826

Phase2, Recruiting

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Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy

for
Relapsed or Refractory Large B-cell Lymphoma
Location: Duarte CA, Goodyear AZ, Stanford CA, Denver CO,
Sponsor: Kite, A Gilead Company

Sex: All

Age: 18+

Code: NCT07479797

Phase3, Recruiting

CAR-T Long Term Follow Up (LTFU) Study

for
Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program,
Location: Duarte CA, Los Angeles CA, Stanford CA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 0 - 70+

Code: NCT02445222

Phase3, Recruiting

Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer

for
Platinum-Resistant Ovarian Carcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: Female

Age: 18+

Code: NCT05225363

Phase1, Recruiting

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

for
Meningioma
Location: Santa Monica CA, Phoenix AZ, San Antonio TX, Houston TX,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT07428616

Phase2, Recruiting

A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia

for
Recurrent Severe Aplastic Anemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 0 - 70+

Code: NCT05757310

Phase1, Recruiting

Early Onset Colorectal Cancer Detection

for
Colorectal Cancer, Colorectal Neoplasms,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 50

Code: NCT06342401

Recruiting

Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Duarte CA, Rochester NY, Boston MA
Sponsor: City of Hope Medical Center

Sex: All

Age: 65+

Code: NCT06042569

Phase2, Recruiting

Circulating Biomarkers in the Development of Type 1 Diabetes

for
Diabetes
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 0+

Code: NCT05505669

Recruiting

Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

for
Relapsed and/or Refractory B-cell Lymphoma
Location: Duarte CA, Gilbert AZ, Stanford CA, Austin TX,
Sponsor: Kite, A Gilead Company

Sex: All

Age: 18+

Code: NCT04989803

Phase1, Phase2, Recruiting

Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06735690

Early_phase1, Recruiting

Phase 1 Study of C.001 in Retinal Degeneration

for
Geographic Atrophy, Stargardt Disease, RPE-mediated Maculopathy,
Location: Beverly Hills CA
Sponsor: Cellio Therapeutics Inc

Sex: All

Age: 18+

Code: NCT07594236

Phase1, Recruiting

BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

for
Advanced Malignancies, Ovarian Cancer, T-cell Lymphoma,
Location: Duarte CA, Philadelphia PA, New York NY
Sponsor: BioInvent International AB

Sex: All

Age: 18+

Code: NCT04752826

Phase1, Phase2, Recruiting

An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

for
Pulmonary Arterial Hypertension
Location: Torrance CA, Beverly Hills CA, Santa Barbara CA,
Sponsor: Inhibikase Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07365332

Phase3, Recruiting

Final Prototype Refinement of Adaptive Cell Phone Support

for
Medication Adherence
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles

Sex: All

Age: 15 - 20

Code: NCT07084155

Recruiting

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

for
T-cell Lymphoma, Cutaneous/Peripheral T-Cell Lymphoma,
Location: Duarte CA, Los Angeles CA, Scottsdale AZ, Aurora CO,
Sponsor: SciTech Development, Inc.

Sex: All

Age: 18+

Code: NCT04234048

Phase1, Recruiting