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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes

for
Diabetes Mellitus, Type 1
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 68

Code: NCT03746769

Phase1, Phase2, Recruiting

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

for
Persistent Corneal Epithelial Defect
Location: Laguna Hills CA, Huntington Beach CA, Redlands CA,
Sponsor: Dompé Farmaceutici S.p.A

Sex: All

Age: 18+

Code: NCT07519902

Phase3, Recruiting

A2-ESO-1 TCR-Engineered T Cells for Relapsed/Refractory Advanced or Metastatic NY-ESO-1 Overexpression Positive Triple Negative Breast Cancer

for
Triple Negative Breast Cancer
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: Female

Age: 18+

Code: NCT05989828

Phase1, Recruiting

Study of Aritinercept in Patients With Generalized Myasthenia Gravis

for
Myasthenia Gravis, Generalized
Location: Pasadena CA, Houston TX, O'Fallon IL, Chicago IL,
Sponsor: Aurinia Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT07596901

Phase1, Phase2, Recruiting

Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica

for
Polymyalgia Rheumatica
Location: Tustin CA, Huntington Beach CA, Temecula CA,
Sponsor: Sanofi

Sex: All

Age: 50+

Code: NCT07286214

Recruiting

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A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD

for
Pulmonary Hypertension Due to Lung Disease (Disorder)
Location: Los Angeles CA, Phoenix AZ, Scottsdale AZ,
Sponsor: Liquidia Technologies, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07285655

Phase3, Recruiting

Early Detection of Advanced Adenomas and Colorectal Cancer

for
Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp,
Location: Monrovia CA, San Diego CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06342440

Recruiting

A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

for
Colitis, Ulcerative, Crohn Disease
Location: Los Angeles CA, Oxnard CA, Las Vegas NV, Englewood CO,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07483073

Phase2, Recruiting

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70

Code: NCT06287944

Phase1, Recruiting

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors, Colorectal Cancer,
Location: Los Angeles CA, San Francisco CA, Aurora CO, Seattle WA,
Sponsor: ArriVent BioPharma, Inc.

Sex: All

Age: 18+

Code: NCT07066657

Phase1, Recruiting

To Evaluate the Preliminary Efficacy of Our Digitally Enhanced CHW-led Intervention in Newly Diagnosed PDAC

for
Pancreatic Cancer, Adult
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: All

Age: 1+

Code: NCT07591571

Recruiting

Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

for
Recurrent Grade 1 Follicular Lymphoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06453044

Phase2, Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for
Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung,
Location: Duarte CA, Phoenix AZ, Scottsdale AZ, Salt Lake City UT,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT06131840

Phase1, Recruiting

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

for
Focal Seizure, Epilepsy, Focal Epilepsy
Location: Palmdale CA, Boise ID, Gulf Breeze FL, Fort Wayne IN,
Sponsor: Rapport Therapeutics Inc.

Sex: All

Age: 18 - 70+

Code: NCT07563881

Phase3, Recruiting

Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations

for
Chronic Disease, Infectious Disorder
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT04160429

Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 60+

Code: NCT06195891

Phase1, Recruiting

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

for
Chronic Graft-versus-host-disease
Location: Duarte CA, Los Angeles CA, La Jolla CA,
Sponsor: Incyte Corporation

Sex: All

Age: 12+

Code: NCT06585774

Phase3, Recruiting

A Single Dose, Phase 1 Study of JADE101 in Healthy Japanese and Chinese Participants

for
Healthy Volunteers (HV)
Location: Glendale CA
Sponsor: Jade Biosciences, Inc.

Sex: All

Age: 18 - 55

Code: NCT07525947

Phase1, Recruiting

A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors

for
Advanced NRAS-Mutant Melanoma,
Location: Los Angeles CA, San Francisco CA, Aurora CO,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07584226

Phase1, Recruiting

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

for
Small Cell Lung Cancer (SCLC),
Location: Duarte CA, Los Angeles CA, Portland OR, Seattle WA,
Sponsor: Phanes Therapeutics

Sex: All

Age: 18+

Code: NCT05652686

Phase1, Phase2, Recruiting