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Paid Clinical Trials Orlando

Discover 1,033 paid clinical trials in Orlando, Florida. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for
Triple Negative Breast Neoplasms
Location: Orlando FL, Altamonte Springs FL, West Palm Beach FL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06841354

Phase 3, Recruiting
Active & Responsive

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

for
Cutaneous Melanoma
Location: Orlando FL, Ocoee FL, Lake Mary FL, Lakeland FL,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 70+

Code: NCT07068074

Phase 3, Recruiting
Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Orlando FL, Gainesville FL, Jacksonville FL, Miami FL,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase 3, Recruiting
Active & Responsive

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Orlando FL, Nashville TN, Washington D.C. DC,
Sponsor: ModernaTX, Inc.

Sex: All

Age: 12+

Code: NCT05533697

Phase 1, Phase 2, Recruiting
Active & Responsive

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for
Advanced Melanoma
Location: Orlando FL, Jacksonville FL, Atlanta GA, Spartanburg SC,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT05549297

Phase 3, Recruiting

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Active & Responsive

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for
Acute Ischemic Stroke
Location: Orlando FL, Tampa FL, Sarasota FL, Jacksonville FL,
Sponsor: Mercy Health Ohio

Sex: All

Age: 18 - 70+

Code: NCT05611242

Phase 3, Recruiting
Active & Responsive

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

for
Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary,
Location: Orlando FL, Tampa FL, Clearwater FL, Jacksonville FL,
Sponsor: GT Medical Technologies, Inc.

Sex: All

Age: 0+

Code: NCT04427384

Recruiting
Active & Responsive

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

for
Emphysema, Pulmonary, Emphysema or COPD
Location: Orlando FL, Knoxville TN, Lexington KY, Falls Church VA,
Sponsor: Pulmonx Corporation

Sex: All

Age: 40 - 70+

Code: NCT06035120

Recruiting
Active & Responsive

Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

for
Weight Regain, Weight Loss
Location: Orlando FL, Tampa FL, Jacksonville FL, Houston TX,
Sponsor: Boston Scientific Corporation

Sex: All

Age: 18+

Code: NCT07015424

Recruiting
Active & Responsive

Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection

for
Barrett Esophagus, Barrett Adenocarcinoma, Esophagus Neoplasm
Location: Orlando FL
Sponsor: Universitätsklinikum Hamburg-Eppendorf

Sex: All

Age: 18 - 70+

Code: NCT03427346

Recruiting
Active & Responsive

Comparing the Efficacy and Safety of the EndoZip System and Apollo ESG in Obese Patients

for
Obesity, Overweight
Location: Orlando FL, New York NY, Los Angeles CA
Sponsor: Nitinotes Surgical Ltd.

Sex: All

Age: 21 - 65

Code: NCT07090005

Recruiting
Active & Responsive

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Orlando FL, Kissimmee FL, Fuquay-Varina NC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819878

Phase 3, Recruiting
Active & Responsive

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for
Treatment Resistant Depression
Location: Orlando FL, Tampa FL, Boca Raton FL, Hialeah FL,
Sponsor: LivaNova

Sex: All

Age: 18+

Code: NCT03887715

Recruiting
Active & Responsive

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: Orlando FL, Fort Lauderdale FL, Charleston SC,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07091617

Recruiting
Active & Responsive

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for
Lymphoblastic Leukemia
Location: Orlando FL, Norfolk VA, Little Rock AR, Houston TX,
Sponsor: Tanja Andrea Gruber

Sex: All

Age: 0 - 1

Code: NCT05848687

Phase 1, Phase 2, Recruiting
Active & Responsive

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for
Pleuropulmonary Blastoma
Location: Orlando FL, Tampa FL, St. Petersburg FL,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT06647953

Phase 3, Recruiting
Active & Responsive

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

for
Alzheimer Disease
Location: Orlando FL, Ocoee FL, The Villages FL, Daytona Beach FL,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 55 - 70+

Code: NCT06585787

Phase 3, Recruiting
Active & Responsive

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

for
Overweight, Obesity
Location: Orlando FL, The Villages FL, New Port Richey FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07589608

Phase 2, Recruiting
Active & Responsive

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

for
Depressive Disorder, Major
Location: Orlando FL, Maitland FL, Orange City FL, Tampa FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07412756

Phase 3, Recruiting
Active & Responsive

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

for
Obesity, Overweight
Location: Orlando FL, The Villages FL, New Port Richey FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT06143956

Phase 2, Recruiting

Orlando, Florida has a well-developed healthcare system with several prominent medical research facilities, making it an important hub for a diverse array of clinical trials. Notable institutions such as the Orlando Health Cancer Institute and the University of Central Florida's College of Medicine are at the forefront of these research initiatives.

Each medical center in Orlando focuses on innovative studies across various fields, including oncology, cardiovascular health, and neurological disorders, positioning Orlando as a vital contributor in advancing medical research and treatment options.

Why choose Orlando for clinical trials?

Orlando offers a vast array of advantages for individuals considering participation in clinical trials. The city is home to a diverse population, which helps create a wide range of participants, enhancing the reliability and applicability of research findings.

Additionally, Orlando’s thriving healthcare ecosystem fosters an environment of innovation and collaboration, with a strong emphasis on advancing medical research and treatment. By participating in a clinical trial in Orlando, participants not only gain access to innovative therapies but also play a crucial role in advancing scientific knowledge.

Common conditions studied in Orlando

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How to enroll in a clinical trial in Orlando