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Paid Clinical Trials Chicago

Discover 2,385 paid clinical trials in Chicago, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Communication Bridge 3 Study

for
Primary Progressive Aphasia
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18 - 70+

Code: NCT06191198

Phase 2, Recruiting
Active & Responsive

Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

for
Parenteral Nutrition Associated Liver Disease (PNALD),
Location: Chicago IL, Cincinnati OH, Nashville TN,
Sponsor: Fresenius Kabi

Sex: All

Age: 0 - 17

Code: NCT06274788

Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for
Crohn's Disease
Location: Chicago IL, Evanston IL, Gurnee IL, Indianapolis IN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 16 - 70+

Code: NCT06430801

Phase 3, Recruiting
Active & Responsive

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for
PIK3CA Mutation, Solid Tumor, Adult,
Location: Chicago IL, Madison WI, Indianapolis IN, Ann Arbor MI,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05216432

Phase 1, Recruiting
Active & Responsive

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for
Ductal Carcinoma in Situ
Location: Chicago IL, Saint Paul MN, Minneapolis MN,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female

Age: 18+

Code: NCT06075953

Phase 2, Recruiting

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Active & Responsive

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

for
Type 1 Diabetes Mellitus With Hypoglycemia
Location: Chicago IL, Indianapolis IN, Flint MI, Columbia OH,
Sponsor: Zucara Therapeutics Inc.

Sex: All

Age: 18 - 70+

Code: NCT05762107

Phase 2, Recruiting
Active & Responsive

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

for
Schizophrenia Spectrum and Other Psychotic Disorders,
Location: Chicago IL, Athens GA, Hartford CT, Dallas TX,
Sponsor: Beth Israel Deaconess Medical Center

Sex: All

Age: 18 - 40

Code: NCT06740383

Recruiting
Active & Responsive

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for
Cesarean Delivery, General Anesthesia
Location: Chicago IL, Indianapolis IN, Iowa City IA,
Sponsor: Yale University

Sex: Female

Age: 15 - 55

Code: NCT06030063

Recruiting
Active & Responsive

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

for
HER2-positive Metastatic Breast Cancer
Location: Chicago IL, Orland Park IL, New Lenox IL,
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06551116

Recruiting
Active & Responsive

A Study of PHST001 in Advanced Solid Tumors

for
Advanced Solid Tumors, Ovarian Cancer, Endometrial Cancer,
Location: Chicago IL, Grand Rapids MI, Ann Arbor MI, Denver CO,
Sponsor: Pheast Therapeutics

Sex: All

Age: 18+

Code: NCT06840886

Phase 1, Recruiting
Active & Responsive

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for
Carcinoma, Non-Small-Cell Lung
Location: Chicago IL, Peoria IL, Indianapolis IN, Cincinnati OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06623422

Phase 3, Recruiting
Active & Responsive

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for
Lymphoma, Non-Hodgkin, B-cell Lymphoma,
Location: Chicago IL, Milwaukee WI, Ann Arbor MI, Iowa City IA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07101328

Phase 1, Recruiting
Active & Responsive

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

for
Primary Myelofibrosis (PMF),
Location: Chicago IL, Indianapolis IN, Columbus OH, Fargo ND,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07357727

Phase 3, Recruiting
Active & Responsive

A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)

for
Urothelial Carcinoma
Location: Chicago IL, Indianapolis IN, Cleveland OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05562830

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

for
FGFR2 Gene Fusion/Rearrangement, Other Solid Tumors, Adult
Location: Chicago IL, New York NY, Boston MA, Houston TX,
Sponsor: Elevar Therapeutics

Sex: All

Age: 18+

Code: NCT07359820

Phase 2, Recruiting
Active & Responsive

KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for
Bladder Cancer
Location: Chicago IL, Cleveland OH, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07232602

Phase 1, Phase 2, Recruiting
Active & Responsive

Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS

for
Short Bowel Syndrome
Location: Chicago IL, St Louis MO, Nashville TN, Pittsburgh PA,
Sponsor: Zealand Pharma

Sex: All

Age: 18 - 70+

Code: NCT07197944

Phase 3, Recruiting
Active & Responsive

Pharmacokinetic and Early Efficacy of OPT101 in Patients With Type 1 Diabetes Mellitus

for
Type I Diabetes
Location: Chicago IL, Birmingham AL, Aurora CO, Renton WA,
Sponsor: Op-T LLC

Sex: All

Age: 18 - 50

Code: NCT06964087

Phase 2, Recruiting
Active & Responsive

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Chicago IL, Detroit MI, St Louis MO, Nashville TN,
Sponsor: ModernaTX, Inc.

Sex: All

Age: 12+

Code: NCT05533697

Phase 1, Phase 2, Recruiting
Active & Responsive

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

for
Non-small Cell Lung Cancer, NSCLC
Location: Chicago IL, Ypsilanti MI, Minneapolis MN, Kitchener,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06422143

Phase 3, Recruiting

Chicago is a vital city for clinical research, offering a robust healthcare network and renowned medical research institutions. Major facilities such as The University of Chicago Medicine, Northwestern Medicine, and Rush University Medical Center are at the forefront of pioneering research across various fields, including cancer, cardiovascular health, and neurological disorders.

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Looking for women's health studies in Chicago? Read our guide: Top 10 Women's Health Clinical Trials in Chicago

Top 10 Women’s Health Clinical Trials in Chicago

Why choose Chicago for clinical trials?

The city of Chicago offers many advantages for individuals considering participation in clinical trials. With a diverse and vibrant population, researchers benefit from the variety of participants, improving the reliability and applicability of research findings across different demographics.

By opting to participate in a clinical trial in Chicago, individuals not only gain access to cutting-edge therapies and treatments but also contribute to vital medical research. This collaborative effort is supported by a robust clinical research infrastructure, ensuring participants receive high-quality care and attention while playing a crucial role in shaping the future of healthcare.

Common conditions studied in Chicago

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Benefits of participating in clinical trials

How to enroll in a clinical trial in Chicago