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Paid Clinical Trials Chicago

Discover 2,385 paid clinical trials in Chicago, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

for
Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR),
Location: Zion IL, Indianapolis IN, Nashville TN, Toronto,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07403721

Phase 1, Recruiting

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

for
Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD
Location: Chicago IL, Oak Park IL, Oak Forest IL, Carmel IN,
Sponsor: Adverum Biotechnologies, Inc.

Sex: All

Age: 50+

Code: NCT07482176

Phase 3, Recruiting

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Zion IL, Milwaukee WI, Ann Arbor MI, Iowa City IA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07258511

Phase 3, Recruiting

A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants

for
Gout
Location: Chicago IL, Dayton OH, Troy MI, Sterling Heights MI,
Sponsor: Crystalys Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07535034

Phase 2, Recruiting

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative,
Location: Chicago IL, Phoenix AZ, Duarte CA, Irvine CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 54

Code: NCT06918431

Phase 2, Recruiting

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A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

for
Alzheimer's Disease
Location: Chicago IL, Toronto, Peterborough, Arlington VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 55 - 70+

Code: NCT07717411

Phase 3, Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

for
Ovarian Neoplasms, Ovarian Cancer
Location: Arlington Heights IL, Fort Wayne IN, Indianapolis IN,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07318558

Phase 3, Recruiting

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

for
Mild Cognitive Impairment, Alzheimer's Disease,
Location: Chicago IL, Farmington Hills MI, Toronto,
Sponsor: GAP Innovations, PBC

Sex: All

Age: 60 - 70+

Code: NCT06584357

Recruiting

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Chicago IL, Grand Rapids MI, Newnan GA, Denver CO,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07409246

Phase 1, Recruiting

Prospective Randomized Trial Comparing Longitudinal vs. Transverse A1 Pulley Release

for
Trigger Finger, Stenosing Tenosynovitis
Location: Chicago IL, St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07516652

Recruiting

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for
Non-small Cell Lung Cancer (NSCLC)
Location: Chicago IL, Evanston IL, Peoria IL, Fort Wayne IN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07361497

Phase 3, Recruiting

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)

for
GIST - Gastrointestinal Stromal Tumor, GIST,
Location: Chicago IL, Ann Arbor MI, Iowa City IA, Rochester MN,
Sponsor: Kumquat Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07406633

Phase 2, Recruiting

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

for
Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT04747912

Phase 2, Recruiting

A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States

for
Non-Muscle Invasive Bladder Neoplasms
Location: Chicago Ridge IL, Indianapolis IN, Troy MI, St Louis MO,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07309445

Recruiting

A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)

for
Chronic Graft-versus-host-disease
Location: Chicago IL, Detroit MI, St Louis MO, Columbus OH,
Sponsor: Syndax Pharmaceuticals

Sex: All

Age: 2+

Code: NCT04710576

Phase 2, Recruiting

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

for
Lupus Erythematosus, Systemic
Location: Willowbrook IL, Sterling Heights MI,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18 - 70+

Code: NCT07438496

Phase 3, Recruiting

A Study Evaluating The Combination of Immunotherapy With Radiotherapy in Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, Metastatic Lung Cancer
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT07603856

Phase 2, Recruiting

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for
Gastric Cancer, Gastroesophageal Junction Adenocarcinoma,
Location: Niles IL, Grand Rapids MI, Indianapolis IN, St Louis MO,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07431281

Phase 3, Recruiting

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma, PDAC
Location: Chicago IL, Zion IL, Grand Rapids MI, St Louis MO,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07490301

Phase 2, Phase 3, Recruiting

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Chicago IL, Zion IL, Madison WI, Grand Rapids MI,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07365241

Phase 3, Recruiting

Chicago is a vital city for clinical research, offering a robust healthcare network and renowned medical research institutions. Major facilities such as The University of Chicago Medicine, Northwestern Medicine, and Rush University Medical Center are at the forefront of pioneering research across various fields, including cancer, cardiovascular health, and neurological disorders.

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Looking for women's health studies in Chicago? Read our guide: Top 10 Women's Health Clinical Trials in Chicago

Top 10 Women’s Health Clinical Trials in Chicago

Why choose Chicago for clinical trials?

The city of Chicago offers many advantages for individuals considering participation in clinical trials. With a diverse and vibrant population, researchers benefit from the variety of participants, improving the reliability and applicability of research findings across different demographics.

By opting to participate in a clinical trial in Chicago, individuals not only gain access to cutting-edge therapies and treatments but also contribute to vital medical research. This collaborative effort is supported by a robust clinical research infrastructure, ensuring participants receive high-quality care and attention while playing a crucial role in shaping the future of healthcare.

Common conditions studied in Chicago

Local regulations and guidelines

Benefits of participating in clinical trials

How to enroll in a clinical trial in Chicago