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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Body Image and Self-Care in HIV-Infected MSM

for
Body Image Disturbance, Medication Adherence
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: Male

Age: 18 - 65

Code: NCT01817621

Recruiting

Cognitive Control Training as an Adjunct to Behavioral Activation Therapy in the Treatment of Depression

for
Depression
Location: Boston MA
Sponsor: Boston University

Sex: All

Age: 18 - 65

Code: NCT01694719

Recruiting

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

for
Chronic Obstructive Pulmonary Disease
Location: Boston MA, Flushing NY, East Orange NJ, Philadelphia PA,
Sponsor: Sanofi

Sex: All

Age: 40 - 70+

Code: NCT07190209

Phase3, Recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

for
Dystonia
Location: Boston MA, New York NY, Philadelphia PA, Rochester NY,
Sponsor: Vima Therapeutics

Sex: All

Age: 18 - 70

Code: NCT07304089

Phase2, Recruiting

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for
Solid Tumors
Location: Boston MA, Lake Success NY, The Bronx NY, Hackensack NJ,
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT07522073

Phase3, Recruiting

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Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

for
Chronic Obstructive Pulmonary Disease
Location: New Bedford MA, New Windsor NY, Newark NJ, Hamilton NJ,
Sponsor: Sanofi

Sex: All

Age: 40 - 70+

Code: NCT07190222

Phase3, Recruiting

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

for
Advanced Or Metastatic Merkel Cell Carcinoma
Location: Boston MA, Hackensack NJ, Morristown NJ, Fairfax VA,
Sponsor: TuHURA Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT06947928

Phase2, Phase3, Recruiting

A Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan for Injection in Participants With Advanced Solid Tumors (BEHOLD-1)

for
Solid Tumors, Neoplasms
Location: Boston MA, Mineola NY, New York NY, Toronto, Montreal,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06431594

Phase1, Recruiting

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for
Non-small Cell Lung Cancer (NSCLC)
Location: Boston MA, South Portland ME, East Syracuse NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07291037

Phase3, Recruiting

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

for
Chronic Lymphocytic Leukemia (CLL),
Location: Boston MA, Durham NC, Winston-Salem NC, Charlotte NC
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07024706

Phase2, Recruiting

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

for
Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer,
Location: Boston MA, Commack NY, Ottawa, Baltimore MD, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05123482

Phase1, Phase2, Recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for
Metastatic Non-small Cell Lung Cancer
Location: Boston MA, The Bronx NY, New York NY, Morristown NJ,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06417814

Phase3, Recruiting

AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

for
Lymphoma, Non-Hodgkin Lymphoma, Hodgkin Lymphoma,
Location: Boston MA, New York NY, Philadelphia PA, Miami FL,
Sponsor: AstraZeneca

Sex: All

Age: 12+

Code: NCT06137144

Phase1, Phase2, Recruiting

A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

for
Autoimmune Haemolytic Anaemia
Location: Boston MA, Providence RI, New Haven CT, The Bronx NY,
Sponsor: Sanofi

Sex: All

Age: 18+

Code: NCT07086976

Phase3, Recruiting

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Boston MA, New Haven CT, Montreal, Baltimore MD,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05061550

Phase2, Recruiting

Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial

for
Critical Illness, Post Operative Complication, Thoracic Surgery
Location: Boston MA
Sponsor: Wandercraft

Sex: All

Age: 18+

Code: NCT07220733

Phase1, Phase2, Recruiting

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for
Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma,
Location: Boston MA, Providence RI, New York NY, Hackensack NJ,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06564038

Phase1, Phase2, Recruiting

A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

for
Acute Migraine
Location: Boston MA, Waltham MA, Waterbury CT, Commack NY,
Sponsor: Kallyope Inc.

Sex: All

Age: 18+

Code: NCT07674654

Phase3, Recruiting

A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)

for
Inflammatory Arthritis,
Location: Newton MA, New York NY, Charleston SC
Sponsor: Smith & Nephew, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07199738

Recruiting

A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies

for
HIV
Location: Boston MA, Atlanta GA, Birmingham AL, Seattle WA
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 60

Code: NCT07569029

Phase1, Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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