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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks

for
Amputation
Location: Cambridge MA
Sponsor: Massachusetts Institute of Technology

Sex: All

Age: 18 - 70

Code: NCT07645729

Recruiting

Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis

for
Knee Osteoarthristis
Location: Cambridge MA
Sponsor: Massachusetts Institute of Technology

Sex: All

Age: 21 - 70+

Code: NCT07652437

Recruiting

Active Knee Prosthesis Study for Improvement of Locomotion for Above Knee Amputees

for
Amputation
Location: Cambridge MA, North Andover MA
Sponsor: Providence VA Medical Center

Sex: All

Age: 18 - 50

Code: NCT00771589

Recruiting

Muscle Response to Different Amounts of Dietary Protein During Leg Immobilization

for
Muscle Disuse, Muscle Disuse Atrophy
Location: Natick MA
Sponsor: United States Army Research Institute of Environmental Medicine

Sex: All

Age: 17 - 39

Code: NCT07069426

Recruiting

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Location: Boston MA, Hawthorne NY, Richmond VA, Columbus OH,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07063745

Phase2, Phase3, Recruiting

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A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

for
Familial Pulmonary Fibrosis, Interstitial Lung Abnormalities,
Location: Boston MA, New York NY, Montreal, Philadelphia PA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 40+

Code: NCT07201922

Phase3, Recruiting

Horizon Two: HR NDMM (MMRC-100)

for
High Risk Newly Diagnosed Multiple Myeloma
Location: Boston MA, New York NY, Detroit MI, Chapel Hill NC,
Sponsor: Multiple Myeloma Research Consortium

Sex: All

Age: 18+

Code: NCT07053436

Phase2, Recruiting

Video Inspired Discussions About Ethical Outcomes in Pediatrics

for
Pediatric Cancer
Location: Boston MA, Atlanta GA, Birmingham AL
Sponsor: Massachusetts General Hospital

Sex: All

Age: 0+

Code: NCT06786104

Recruiting

Mechanisms Of Orbitofrontal Stimulation in Depression

for
Major Depressive Disorder (MDD)
Location: Boston MA
Sponsor: Subha Subramanian

Sex: All

Age: 18 - 65

Code: NCT07230990

Recruiting

A Phase 2 Study to Evaluate the Safety and Efficacy of Pacritinib in Relapsed or Refractory Waldenström Macroglobulinemia

for
Waldenström Macroglobulinemia, Lymphoplasmacytic Lymphoma,
Location: Boston MA
Sponsor: Shayna Sarosiek, MD

Sex: All

Age: 18+

Code: NCT06986174

Phase2, Recruiting

Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

for
Diabetes Mellitus, Type 2
Location: Boston MA, Columbus OH, Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT06251323

Recruiting

ACTengine® IMA203 Combined With mRNA-4203

for
Cutaneous Melanoma, Synovial Sarcoma
Location: Boston MA, New York NY, Houston TX, San Francisco CA
Sponsor: Immatics US, Inc.

Sex: All

Age: 18+

Code: NCT06946225

Phase1, Recruiting

Osseointegrated Transtibial Prosthesis With Neural Interface

for
Amputation
Location: Cambridge MA, Boston MA
Sponsor: Massachusetts Institute of Technology

Sex: All

Age: 22 - 65

Code: NCT05249049

Recruiting

A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone

for
Postpartum Depression
Location: Cambridge MA
Sponsor: Biogen

Sex: Female

Age: 18+

Code: NCT07398469

Recruiting

A Clinical Trial Assessing the Safety and Effectiveness of the DurAVR® THV System

for
Severe Aortic Stenosis, Valve-in-valve Procedures
Location: Boston MA, The Bronx NY, Baltimore MD, Cleveland OH,
Sponsor: Anteris Technologies Ltd.

Sex: All

Age: 18+

Code: NCT07194265

Recruiting

A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine

for
Lyme Disease
Location: Worcester MA, Sherbrooke, Scranton PA, Cortland NY,
Sponsor: Pfizer

Sex: All

Age: 7+

Code: NCT07500506

Phase3, Recruiting

Real-world Patient Reported Outcomes Among Patients Treated With Camzyos

for
Obstructive Hypertrophic Cardiomyopathy
Location: Boston MA
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06551129

Recruiting

A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults

for
COVID-19
Location: Boston MA, Baltimore MD, Decatur GA, St Louis MO,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 64

Code: NCT07536308

Phase1, Recruiting

Effects of Neuromodulation in Laryngeal Dystonia

for
Laryngeal Dystonia, Focal Dystonia
Location: Boston MA
Sponsor: MGH Institute of Health Professions

Sex: All

Age: 21 - 70+

Code: NCT05095740

Recruiting

A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis

for
Neurotrophic Keratitis
Location: Russells Mills MA, New York NY, Carmel IN,
Sponsor: TearSolutions, Inc.

Sex: All

Age: 18+

Code: NCT07568730

Phase2, Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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