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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)

for
Carotid Artery Calcification, Carotid Artery Diseases
Location: Boston MA, New York NY, Buffalo NY, Bay City MI,
Sponsor: Shockwave Medical, Inc.

Sex: All

Age: 18+

Code: NCT07062471

Recruiting

Radiation Free Study

for
Aortic Aneurysm
Location: Worcester MA, Philadelphia PA, Birmingham AL, Dallas TX
Sponsor: Philips Clinical & Medical Affairs Global

Sex: All

Age: 18+

Code: NCT06549348

Recruiting

REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants

for
Symptomatic Venous Thromboembolism (VTE)
Location: Boston MA, Teaneck NJ, New York NY, Hershey PA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07213778

Phase3, Recruiting

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for
Low-grade NMIBC, FGFR Gene Amplification, FGFR Gene Alterations,
Location: Plymouth MA, The Bronx NY, Astoria NY, New York NY,
Sponsor: Tyra Biosciences, Inc

Sex: All

Age: 18+

Code: NCT06995677

Phase2, Recruiting

Safety, Tolerability, and Efficacy of NVG-2089 in Participants With Immune Thrombocytopenia

for
Immune Thrombocytopenia (ITP)
Location: Boston MA, Washington D.C. DC, Greenville NC
Sponsor: Nuvig Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07095127

Phase2, Recruiting

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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

for
Alzheimer Disease
Location: Newton MA, South Dartmouth MA, Springfield MA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 55 - 70+

Code: NCT07011732

Phase3, Recruiting

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

for
AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL),
Location: Boston MA, New York NY, Charlottesville VA, Detroit MI,
Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All

Age: 18 - 66

Code: NCT06859424

Phase2, Recruiting

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

for
Alcohol-Related Disorders, Substance-Related Disorders,
Location: Boston MA, Marlborough MA, Worcester MA, Springfield MA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT05910580

Recruiting

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

for
Lumbar Spinal Stenosis, Cardiac Amyloidosis,
Location: Boston MA, New York NY, Cleveland OH, Beverly Hills CA
Sponsor: Columbia University

Sex: All

Age: 50+

Code: NCT06034405

Recruiting

Toripalimab With Chemotherapy for Sinus Cancer

for
Sinonasal Cancer, Paranasal Sinus Neoplasms,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06940180

Phase2, Recruiting

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

for
Alzheimer Disease and Related Dementias, Cognition,
Location: Roslindale MA
Sponsor: Hebrew SeniorLife

Sex: All

Age: 65 - 70+

Code: NCT06821568

Recruiting

PROspect Registry :Post Market Clinical Follow-up Study

for
Breast Surgery
Location: Boston MA, Jacksonville FL
Sponsor: Stryker Endoscopy

Sex: All

Age: 18+

Code: NCT07631468

Recruiting

Bedtime Stories: Tailored Sleep Health Messaging for Caregivers

for
Sleep, Health-Related Behavior
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 18+

Code: NCT06618040

Recruiting

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

for
HR+ Breast Cancer, Triple Negative Breast Cancer (TNBC),
Location: Boston MA, New Haven CT, Fairfax VA, Pittsburgh PA,
Sponsor: NiKang Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07029399

Phase1, Recruiting

Pulmonary Artery Catheter in Cardiogenic Shock Trial

for
Cardiogenic Shock, Heart Failure
Location: Boston MA
Sponsor: Tufts Medical Center

Sex: All

Age: 18 - 70+

Code: NCT05485376

Recruiting

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for
High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer,
Location: Boston MA, Burlington MA, Springfield MA, Hartford CT,
Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female

Age: 18+

Code: NCT05128825

Phase2, Recruiting

A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

for
Heart Failure, Muscle Atrophy
Location: Boston MA, Cleveland OH
Sponsor: Tufts Medical Center

Sex: All

Age: 18 - 70+

Code: NCT05627440

Recruiting

Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis

for
Microbiome, Cytokines, Plaque, Gingivitis, Gingival Bleeding
Location: Somerville MA
Sponsor: Kenvue Brands LLC

Sex: All

Age: 18 - 60

Code: NCT07501455

Recruiting

Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)

for
Cognitively Healthy People, Alzheimer Disease
Location: Cambridge MA
Sponsor: Massachusetts Institute of Technology

Sex: All

Age: 18 - 70+

Code: NCT07496918

Phase2, Recruiting

Study of Normal Intestinal Development and Disease in Premature and Term Neonates

for
NEC, Necrotizing Enterocolitis, Intestinal Disease,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0 - 2

Code: NCT06681129

Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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