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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Boston MA, Stoneham MA, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04269902

Phase3, Recruiting

A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

for
Sexual Dysfunction, Stem Cell Transplant Complications,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06541002

Recruiting

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for
Childhood Medulloblastoma
Location: Boston MA, Providence RI, Hartford CT, New Haven CT,
Sponsor: Children's Oncology Group

Sex: All

Age: 4 - 21

Code: NCT05382338

Phase3, Recruiting

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

for
Severe Combined Immunodeficiency, X Linked, Gene Therapy
Location: Boston MA, Cincinnati OH, Atlanta GA, Los Angeles CA
Sponsor: David Williams

Sex: Male

Age: 0 - 5

Code: NCT03311503

Phase1, Phase2, Recruiting

Multicenter Evaluation of Near Vision and Outdoor Time in Kids Study

for
Myopia
Location: Boston MA
Sponsor: The University of New South Wales

Sex: All

Age: 4 - 14

Code: NCT06119243

Recruiting

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Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.

for
Lymphatic Malformations
Location: Boston MA, Philadelphia PA, Washington D.C. DC,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 0 - 70+

Code: NCT05948943

Phase2, Phase3, Recruiting

Effect of Theophylline in Pseudohypoparathyroidism

for
PHP Ia, PHP IB, Php1C
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 5 - 21

Code: NCT03718403

Recruiting

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for
Recurrent Lung Non-Small Cell Carcinoma,
Location: Burlington MA, Peabody MA, Beverly MA, Gloucester MA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06616584

Phase2, Phase3, Recruiting
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A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

for
Atopic Dermatitis
Location: Boston MA, Quincy MA, Lebanon NH, New Haven CT,
Sponsor: AbbVie

Sex: All

Age: 18 - 63

Code: NCT06389136

Phase3, Recruiting

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

for
Prostate Cancer (Adenocarcinoma),
Location: Boston MA, Baltimore MD, Myrtle Beach SC,
Sponsor: Acerand Therapeutics (Hong Kong) Limited

Sex: Male

Age: 18+

Code: NCT06801236

Phase1, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for
Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8,
Location: Boston MA, South Weymouth MA, Milford MA, Sanford ME,
Sponsor: NRG Oncology

Sex: Male

Age: 18+

Code: NCT05946213

Phase3, Recruiting

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Boston MA, New York NY, Baltimore MD,
Sponsor: Nuvalent Inc.

Sex: All

Age: 18+

Code: NCT06521554

Phase1, Recruiting

Rett Syndrome Registry

for
Rett Syndrome, Rett Syndrome, Atypical, Genetic Disease,
Location: Boston MA, Philadelphia PA, Baltimore MD,
Sponsor: International Rett Syndrome Foundation

Sex: All

Age: 0 - 70+

Code: NCT05432349

Recruiting

A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum

for
Pyoderma Gangrenosum
Location: Boston MA, Lebanon NH, Lake Success NY, New York NY,
Sponsor: LEO Pharma

Sex: All

Age: 18+

Code: NCT06624670

Phase3, Recruiting

US National OCS Heart Perfusion (OHP) Registry

for
Heart Transplant
Location: Boston MA, New Haven CT, Valhalla NY, The Bronx NY,
Sponsor: TransMedics

Sex: All

Age: 0+

Code: NCT05915299

Recruiting

Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services

for
Epilepsy
Location: Boston MA, Toronto
Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Sex: All

Age: 0 - 1

Code: NCT06082999

Recruiting

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

for
Cardiovascular Diseases, Cardiac Rehabilitation,
Location: Boston MA, Pittsburgh PA
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT06244199

Recruiting

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

for
Mitral Valve Regurgitation
Location: Boston MA, Hartford CT, New Haven CT, Roslyn NY,
Sponsor: Medtronic Cardiovascular

Sex: All

Age: 18+

Code: NCT03242642

Recruiting

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

for
Depressive Disorder, Major
Location: Watertown MA, Farmington CT, Mount Kisco NY,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18 - 70+

Code: NCT06559306

Phase3, Recruiting

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Boston MA, East Stroudsburg PA, Bethlehem PA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03191149

Phase2, Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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