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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Ziftomenib Maintenance Post Allo-HCT

for
Acute Myeloid Leukemia, Acute Myeloid Leukemia in Remission,
Location: Boston MA, Columbus OH
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06440135

Phase1, Recruiting

Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU

for
Consciousness Disorders
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06568536

Recruiting

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for
Metastatic Uveal Melanoma
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Replimune Inc.

Sex: All

Age: 0+

Code: NCT06581406

Phase2, Phase3, Recruiting

Turmeric for Patients With Basal Joint Arthritis

for
Thumb Osteoarthritis
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 40+

Code: NCT03017118

Recruiting

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for
Breast Cancer
Location: Boston MA, Newton MA, South Weymouth MA, Danvers MA,
Sponsor: Stemline Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06492616

Phase3, Recruiting

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A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

for
Locally Advanced Solid Tumors, Metastatic Solid Tumors
Location: Boston MA, Columbus OH, Chicago IL, Athens GA,
Sponsor: Turning Point Therapeutics, Inc.

Sex: All

Age: 12+

Code: NCT03093116

Phase1, Phase2, Recruiting

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

for
Tetraplegia, Spinal Cord Injuries,
Location: Boston MA, Providence RI, Atlanta GA, Houston TX,
Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All

Age: 18 - 70+

Code: NCT00912041

Recruiting

An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease

for
Vanishing White Matter Disease
Location: Boston MA, Montreal, Philadelphia PA, Salt Lake City UT
Sponsor: Calico Life Sciences LLC

Sex: All

Age: 0+

Code: NCT05757141

Phase1, Phase2, Recruiting

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

for
Refractory Angina
Location: Boston MA, Springfield MA, New Haven CT, Roslyn NY,
Sponsor: Shockwave Medical, Inc.

Sex: All

Age: 18+

Code: NCT05102019

Recruiting

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

for
Advanced or Metastatic Solid Tumors, Breast Cancer,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: 858 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06395519

Phase1, Phase2, Recruiting

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Advanced Cancer, Metastatic Cancer, Gastric Cancer,
Location: Boston MA, New York NY, Madison WI, Aurora CO,
Sponsor: I-Mab Biopharma US Limited

Sex: All

Age: 18+

Code: NCT04900818

Phase1, Recruiting

Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

for
Alzheimer's Disease
Location: Boston MA, Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18 - 70+

Code: NCT05658913

Recruiting

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

for
Brainstem Stroke, ALS, Tetraplegia, Spinal Cord Injuries,
Location: Boston MA
Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All

Age: 18 - 70+

Code: NCT06511934

Recruiting

Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer

for
Impaired Cognition, Chemo-brain, Breast Cancer
Location: Boston MA, Salem MA
Sponsor: Massachusetts General Hospital

Sex: Female

Age: 60+

Code: NCT02290834

Recruiting

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

for
Colorectal Cancer, Coffee, Gastrointestinal Microbiome,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05692024

Phase1, Phase2, Recruiting

National Liver Cancer Screening Trial

for
Carcinoma, Hepatocellular, Liver Cancer, Liver Cirrhosis,
Location: Boston MA, Manhasset NY, Philadelphia PA, Richmond VA,
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06084234

Recruiting

Quality of Pediatric Resuscitation in a Multicenter Collaborative

for
Cardiac Arrest, Cardiopulmonary Arrest
Location: Boston MA, Lebanon NH, Albany NY, Stony Brook NY,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0 - 18

Code: NCT02708134

Recruiting

Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI

for
Catheter-related Infections
Location: Boston MA, Newark NJ, Washington DC, Cleveland OH,
Sponsor: Leonard-Meron Biosciences, Inc.

Sex: All

Age: 12+

Code: NCT02901717

Phase3, Recruiting

Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

for
Transthyretin Amyloidosis, Heart Failure,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 65+

Code: NCT05577819

Recruiting

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

for
Non-hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma,
Location: Boston MA
Sponsor: Marcela V. Maus, M.D.,Ph.D.

Sex: All

Age: 18+

Code: NCT06026319

Phase1, Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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