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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer,
Location: Boston MA, New York NY, Ottawa, Washington D.C. DC,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06586515

Phase1, Recruiting

Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia

for
T-Cell Large Granular Lymphocyte Leukemia
Location: Boston MA, New York NY, Columbus OH
Sponsor: Jonathan Brammer

Sex: All

Age: 18+

Code: NCT05592015

Phase2, Recruiting

A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

for
Small Cell Lung Cancer
Location: Boston MA, Hackensack NJ, Buffalo NY, Chicago IL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06780137

Phase1, Phase2, Recruiting

Pilot Randomized Controlled Trial of a Collaborative Agenda-setting Intervention (CASI) for Patients With Ovarian Cancer

for
Ovarian Cancer, Ovarian Neoplasms, Ovarian Carcinoma
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: Female

Age: 18+

Code: NCT06543537

Recruiting

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Burlington MA, Peabody MA, Livonia MI, Canton MI,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07383441

Phase3, Recruiting

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Hereditary Risk Factors for Thyroid Cancer

for
Thyroid Cancer
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 0+

Code: NCT02747888

Recruiting

A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

for
Irritable Bowel Syndrome
Location: Boston MA, New Windsor NY, North Massapequa NY,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 70+

Code: NCT07519395

Phase2, Recruiting

Investigation of the Delve Detect Cerebrospinal Fluid (CSF) Metagenomic Next-generation Sequencing (mNGS) Test When Used for the Initial Diagnostic Workup of Patients With Suspected Central Nervous System (CNS) Infection

for
Central Nervous System Infection
Location: Burlington MA, Atlanta GA, Nashville TN,
Sponsor: Delve Bio, Inc.

Sex: All

Age: 0+

Code: NCT07435649

Recruiting

A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

for
Acute Treatment of Migraine
Location: Worcester MA, McLean VA, Greensboro NC, Ann Arbor MI,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07609914

Recruiting

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

for
Cutaneous T Cell Lymphoma, Peripheral T Cell Lymphoma
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04045470

Recruiting

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

for
Head and Neck Squamous Cell Carcinoma, Head and Neck Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT05726370

Phase2, Recruiting

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

for
Advanced Systemic Mastocytosis (AdvSM),
Location: Boston MA, Toronto, Charleston SC, Atlanta GA,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT04996875

Phase2, Recruiting

Long-term Follow-up of Participants Treated With Galapagos Chimeric Antigen Receptor (CAR) T-cell Therapies

for
Hematological Malignancies
Location: Boston MA
Sponsor: Lakefront Biotherapeutics NV

Sex: All

Age: 18+

Code: NCT06652633

Phase3, Recruiting

A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health

for
Sudan Virus Disease
Location: Boston MA, Washington D.C. DC, Lenexa KS
Sponsor: International AIDS Vaccine Initiative

Sex: All

Age: 18 - 50

Code: NCT07565090

Phase1, Recruiting

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

for
Cognitive Dysfunction, Lewy Body Disease, Synucleinopathies,
Location: Foxborough MA, Plymouth MA, Stamford CT, Fairfax VA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 55 - 70+

Code: NCT07589595

Phase2, Recruiting

Study of Cordycepin Plus Pentostatin in Patients With Refractory TdT-Positive Leukemia

for
Refractory TdT-Positive Leukemia
Location: Boston MA, San Antonio TX
Sponsor: OncoVista, Inc.

Sex: All

Age: 18+

Code: NCT00709215

Phase1, Phase2, Recruiting

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Boston MA, New York NY, Washington D.C. DC, Durham NC,
Sponsor: OncoC4, Inc.

Sex: All

Age: 18+

Code: NCT06635785

Phase1, Phase2, Recruiting
New

ACTIVATE: AI-driven Clinical-trial Trial-Information and Viability Assessment Tool for EHRs

for
Cancer
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07232043

Recruiting
New

Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes

for
Prostate Cancer, Hot Flashes, Vasomotor Symptoms
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: Male

Age: 18+

Code: NCT07729150

Recruiting

Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for
Epiretinal Membrane
Location: Boston MA, Ayer MA, Liverpool NY, Philadelphia PA,
Sponsor: Jaeb Center for Health Research

Sex: All

Age: 50+

Code: NCT05145491

Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

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