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Paid Clinical Trials Worcester

Discover 3,097 paid clinical trials in Worcester, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

for
Non Small Cell Lung Carcinoma
Location: Boston MA, Shirley NY, East Brunswick NJ, Easton PA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06772623

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

for
Metastatic Breast Cancer
Location: Boston MA, Montreal, Quebec, Hyattsville MD,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT05894239

Phase3, Recruiting
Featured

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Boston MA, New Haven CT, Montreal, Fairfax VA, Toronto,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06820463

Phase2, Recruiting
Featured

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Boston MA, New Haven CT, Lebanon NH, New York NY,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT04302025

Phase2, Recruiting
Featured

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Boston MA, Bethlehem PA, Fairfax VA, Winchester VA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07365241

Phase3, Recruiting

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Featured

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Boston MA, New Haven CT, Fairfax VA, Cleveland OH,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07155174

Phase2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Boston MA, New Haven CT, New York NY, Chapel Hill NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06953960

Phase1, Phase2, Recruiting
Featured

A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

for
Huntington Disease
Location: Boston MA, Philadelphia PA, Pittsburgh PA, Columbus OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 25 - 65

Code: NCT06826612

Phase1, Phase2, Recruiting
Featured

Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL

for
Relapsed or Refractory Aggressive B-Cell Non-Hodgkins Lymphoma
Location: Boston MA, Albany NY, East Syracuse NY, Fairfax VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06806033

Phase2, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Boston MA, Philadelphia PA, Charlotte NC, Germantown TN,
Sponsor: Hoffmann-La Roche

Sex: Female

Age: 18+

Code: NCT04802759

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for
Parkinson's Disease
Location: Boston MA, New Haven CT, Paramus NJ, New York NY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07174310

Phase3, Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: Boston MA, East Patchogue NY, The Bronx NY,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase1, Phase2, Recruiting
Active & Responsive

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

for
Post Traumatic Stress Disorder
Location: Worcester MA, New York NY, Princeton NJ, Toms River NJ,
Sponsor: Transcend Therapeutics

Sex: All

Age: 18+

Code: NCT07456696

Phase3, Recruiting
Active & Responsive

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for
Major Depressive Disorder
Location: Worcester MA, New York NY, Philadelphia PA, Towson MD,
Sponsor: Syndeio Biosciences, Inc

Sex: All

Age: 18 - 64

Code: NCT07115329

Phase2, Recruiting
Active & Responsive

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for
Major Depressive Disorder
Location: Worcester MA, Boston MA, New York NY, Philadelphia PA,
Sponsor: Definium Therapeutics US, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07592689

Phase3, Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Worcester MA, Watertown MA, Brooklyn NY,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase2, Recruiting
Active & Responsive

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for
Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation
Location: Worcester MA, Boston MA, Lebanon NH, Portland ME,
Sponsor: Chris Goss

Sex: All

Age: 6+

Code: NCT05548283

Recruiting
Active & Responsive

Lupus Landmark Study: A Prospective Registry and Biorepository

for
Systemic Lupus Erythematosus (SLE), Lupus Nephritis,
Location: Worcester MA, Boston MA, Manhasset NY, New York NY,
Sponsor: Lupus Research Alliance

Sex: All

Age: 18 - 70+

Code: NCT05934149

Recruiting
Active & Responsive

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

for
Relapsing Multiple Sclerosis,
Location: Worcester MA, New York NY, Philadelphia PA, Richmond VA,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 55

Code: NCT04047628

Phase3, Recruiting
Active & Responsive

Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-3)

for
ADHD
Location: Worcester MA, Springfield MA, Staten Island NY,
Sponsor: Axsome Therapeutics, Inc.

Sex: All

Age: 12 - 17

Code: NCT07717892

Phase3, Recruiting