Clinical Trials In St. Louis

Discover hundreds of clinical trials in St. Louis.
Search clinical trials in St. Louis by condition or phase.

e.g. Respiratory Diseases

St. Louis•Healthy volunteers: No

Filter results

Results: 1,425

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)

Recruiting

Phase 1

Phase 2

Sponsor:

Pfizer

Location:

Saint Peters, Saint Louis, Florissant, Creve Coeurshow 9 more

Code:

NCT05548127

Conditions

Breast Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

ARV-471

Abemaciclib

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

Recruiting

Phase 3

Sponsor:

Pfizer

Location:

Saint Louis, Creve Coeur, Dothan, Mobileshow 92 more

Code:

NCT04173273

Conditions

Crohn's Disease

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Etrasimod

Placebo

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Recruiting

Phase 1

Sponsor:

MacroGenics

Location:

Saint Louis, Denver, Baltimore, Bostonshow 3 more

Code:

NCT05362773

Conditions

Leukemia, Acute Myeloid

Myelodysplastic Syndromes

Classical Hodgkin Lymphoma

Leukemia, B-cell

Leukemia, Hairy Cell

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MGD024

JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors

Recruiting

Phase 1

Phase 2

Sponsor:

Jacobio Pharmaceuticals Co., Ltd.

Location:

Saint Louis, Phoenix, Scottsdale, Los Angelesshow 11 more

Code:

NCT04720976

Conditions

Solid Tumor

NSCLC

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

JAB-3312

Binimetinib

Pembrolizumab

Sotorasib

Osimertinib

Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

Recruiting

Phase 3

Sponsor:

RayzeBio, Inc.

Location:

Saint Louis, Phoenix, Duarte, Irvineshow 25 more

Code:

NCT05477576

Conditions

GEP-NET

Gastroenteropancreatic Neuroendocrine Tumor

Gastroenteropancreatic Neuroendocrine Tumor Disease

Neuroendocrine Tumors

Carcinoid

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

RYZ101

Everolimus

Sunitinib

Octreotide

Lanreotide

Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis

Recruiting

Phase 3

Sponsor:

United Therapeutics

Location:

Saint Louis, Kansas City, Chesterfield, Birminghamshow 75 more

Code:

NCT04708782

Conditions

Idiopathic Pulmonary Fibrosis

Interstitial Lung Disease

Eligibility Criteria

Sex: All

Age: 40+

Healthy Volunteers: Not accepted

Interventions

Placebo

Inhaled Treprostinil

Treprostinil Ultrasonic Nebulizer

The Impact of an Adaptive Patient-centered Web Application on Medication Optimization in HFrEF Patients

Recruiting

Phase 3

Sponsor:

University of Michigan

Location:

Saint Louis, Atlanta, Ann Arbor, Detroitshow 1 more

Code:

NCT05858320

Conditions

Heart Failure

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

SmartHF application

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Recruiting

Phase 3

Sponsor:

Janssen Research & Development, LLC

Location:

Saint Louis, Little Rock, Los Alamitos, Los Angelesshow 27 more

Code:

NCT06319820

Conditions

Non-Muscle Invasive Bladder Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

TAR-210

Gemcitabine

MMC

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors

Recruiting

Phase 1

Phase 2

Sponsor:

AstraZeneca

Location:

Saint Louis, Providence, Nashville, Houston

Code:

NCT06188520

Conditions

ER+ HER2- Advanced Breast Cancer

High-grade Serous Ovarian Cancer (HGSOC)

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

AZD8421

Camizestrant

Ribociclib

Palbociclib

Abemaciclib

MILD® Percutaneous Image-Guided Lumbar Decompression: a Medicare Claims Study

Recruiting

Sponsor:

Vertos Medical, Inc.

Location:

West Plains, Washington, Troy, Springfieldshow 940 more

Code:

NCT03072927

Conditions

Lumbar Spinal Stenosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MILD

Interspinous Process Decompression

e.g. Respiratory Diseases

St. Louis•Healthy volunteers: No

Filter results

Results: 1,425

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)

Recruiting

Phase 1

Phase 2

Sponsor:

Pfizer

Location:

Saint Peters, Saint Louis, Florissant, Creve Coeurshow 9 more

Code:

NCT05548127

Conditions

Breast Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

ARV-471

Abemaciclib

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

Recruiting

Phase 3

Sponsor:

Pfizer

Location:

Saint Louis, Creve Coeur, Dothan, Mobileshow 92 more

Code:

NCT04173273

Conditions

Crohn's Disease

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Etrasimod

Placebo

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Recruiting

Phase 1

Sponsor:

MacroGenics

Location:

Saint Louis, Denver, Baltimore, Bostonshow 3 more

Code:

NCT05362773

Conditions

Leukemia, Acute Myeloid

Myelodysplastic Syndromes

Classical Hodgkin Lymphoma

Leukemia, B-cell

Leukemia, Hairy Cell

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MGD024

JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors

Recruiting

Phase 1

Phase 2

Sponsor:

Jacobio Pharmaceuticals Co., Ltd.

Location:

Saint Louis, Phoenix, Scottsdale, Los Angelesshow 11 more

Code:

NCT04720976

Conditions

Solid Tumor

NSCLC

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

JAB-3312

Binimetinib

Pembrolizumab

Sotorasib

Osimertinib

Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

Recruiting

Phase 3

Sponsor:

RayzeBio, Inc.

Location:

Saint Louis, Phoenix, Duarte, Irvineshow 25 more

Code:

NCT05477576

Conditions

GEP-NET

Gastroenteropancreatic Neuroendocrine Tumor

Gastroenteropancreatic Neuroendocrine Tumor Disease

Neuroendocrine Tumors

Carcinoid

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

RYZ101

Everolimus

Sunitinib

Octreotide

Lanreotide

Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis

Recruiting

Phase 3

Sponsor:

United Therapeutics

Location:

Saint Louis, Kansas City, Chesterfield, Birminghamshow 75 more

Code:

NCT04708782

Conditions

Idiopathic Pulmonary Fibrosis

Interstitial Lung Disease

Eligibility Criteria

Sex: All

Age: 40+

Healthy Volunteers: Not accepted

Interventions

Placebo

Inhaled Treprostinil

Treprostinil Ultrasonic Nebulizer

The Impact of an Adaptive Patient-centered Web Application on Medication Optimization in HFrEF Patients

Recruiting

Phase 3

Sponsor:

University of Michigan

Location:

Saint Louis, Atlanta, Ann Arbor, Detroitshow 1 more

Code:

NCT05858320

Conditions

Heart Failure

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

SmartHF application

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Recruiting

Phase 3

Sponsor:

Janssen Research & Development, LLC

Location:

Saint Louis, Little Rock, Los Alamitos, Los Angelesshow 27 more

Code:

NCT06319820

Conditions

Non-Muscle Invasive Bladder Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

TAR-210

Gemcitabine

MMC

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors

Recruiting

Phase 1

Phase 2

Sponsor:

AstraZeneca

Location:

Saint Louis, Providence, Nashville, Houston

Code:

NCT06188520

Conditions

ER+ HER2- Advanced Breast Cancer

High-grade Serous Ovarian Cancer (HGSOC)

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

AZD8421

Camizestrant

Ribociclib

Palbociclib

Abemaciclib

MILD® Percutaneous Image-Guided Lumbar Decompression: a Medicare Claims Study

Recruiting

Sponsor:

Vertos Medical, Inc.

Location:

West Plains, Washington, Troy, Springfieldshow 940 more

Code:

NCT03072927

Conditions

Lumbar Spinal Stenosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MILD

Interspinous Process Decompression