Background illustration for clinical trials search

Paid Clinical Trials St. Louis

Discover 1,378 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

Filter
2
FeaturedActive & Responsive

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for
Geographic Atrophy
Location: St Louis MO, Nashville TN, Blue Ash OH, Lynchburg VA,
Sponsor: Genentech, Inc.

Sex: All

Age: 50+

Code: NCT05626114

Phase2, Recruiting
Featured

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma, PDAC
Location: St Louis MO, Chicago IL, Zion IL, Grand Rapids MI,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07490301

Phase2, Phase3, Recruiting
Featured

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: St Louis MO, Columbia MO, Memphis TN, DeKalb IL,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT04302025

Phase2, Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: St Louis MO, Nashville TN, Zion IL, Detroit ME,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase1, Phase2, Recruiting
Featured

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for
Non-Small Cell Lung Cancer
Location: St Louis MO, Westwood KS, Chicago IL, Lexington KY,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06236438

Phase2, Phase3, Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image
Featured

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for
Parkinson's Disease
Location: St Louis MO, Kansas City KS, Memphis TN, Nashville TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07174310

Phase3, Recruiting
Featured

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for
Alzheimers Disease
Location: St Louis MO, Nashville TN, Chicago IL, Knoxville TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07169578

Phase3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

for
Von Willebrand Disease, Type 3
Location: St Louis MO, Lexington KY, Minneapolis MN, Toronto,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0+

Code: NCT06998524

Phase3, Recruiting
Featured

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

for
Atherosclerosis
Location: St Louis MO, Hammond IN, Nashville TN, Omaha NE,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07448038

Phase2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

for
Atopic Dermatitis
Location: St Louis MO, Normal IL, Bowling Green KY,
Sponsor: AbbVie

Sex: All

Age: 2 - 11

Code: NCT06461897

Phase3, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: St Louis MO, Nashville TN, Chicago IL, Knoxville TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase3, Recruiting
Featured

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for
Neovascular Age-related Macular Degeneration
Location: St Louis MO, Springfield IL, Carmel IN, Oak Lawn IL,
Sponsor: AbbVie

Sex: All

Age: 50+

Code: NCT07007065

Phase3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: St Louis MO, Columbia MO, Kansas City KS, Cordova TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Location: St Louis MO, Iowa City IA, Memphis TN, Chicago Ridge IL,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06793215

Phase3, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: St Louis MO, Peoria IL, Urbana IL, Springfield MO,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase2, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: St Louis MO, New Albany IN, Cordova TN, Louisville KY,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase3, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: St Louis MO, New Albany IN, Kansas City KS, Cordova TN,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: O'Fallon IL, Springfield IL, Urbana IL, Kansas City MO,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase3, Recruiting
Featured

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for
Lymphoma
Location: Chesterfield MO, Iowa City IA, Waukee IA, Ann Arbor MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06084936

Phase3, Recruiting
FeaturedNew

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

for
Obesity, Overweight
Location: City of Saint Peters MO, Louisville KY, Nashville TN,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07752979

Phase2, Recruiting