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Paid Clinical Trials St. Louis

Discover 1,406 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: St Louis MO, New Albany IN, Cordova TN, Louisville KY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase 3, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: St Louis MO, New Albany IN, Kansas City KS, Cordova TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase 3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: O'Fallon IL, Springfield IL, Urbana IL, Kansas City MO,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase 3, Recruiting
Featured

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for
Lymphoma
Location: Chesterfield MO, Iowa City IA, Waukee IA, Ann Arbor MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06084936

Phase 3, Recruiting
Featured

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

for
Obesity, Overweight
Location: City of Saint Peters MO, Louisville KY, Nashville TN,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07752979

Phase 2, Recruiting

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Active & Responsive

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Saint Louis MO, Sunset Hills MO, O'Fallon IL, Alton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05929768

Phase 3, Recruiting
Active & Responsive

ALS/MND Natural History Study Data Repository

for
ALS, PLS, MND (Motor Neurone DIsease), Kennedy Disease,
Location: St Louis MO, Chicago IL, Grand Rapids MI, Detroit MI,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT05966038

Recruiting
Active & Responsive

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

for
Chronic Kidney Diseases, End Stage Renal Disease,
Location: St Louis MO, Columbia MO, Memphis TN, Lexington KY,
Sponsor: VenoStent

Sex: All

Age: 18+

Code: NCT06001827

Recruiting
Active & Responsive

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for
Lower Extremity Acute Limb Ischemia, LE ALI
Location: St Louis MO, Jackson TN, Indianapolis IN, Munster IN,
Sponsor: Penumbra Inc.

Sex: All

Age: 18+

Code: NCT06747117

Recruiting
Active & Responsive

Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

for
Chronic Low Back Pain
Location: St Louis MO, Indianapolis IN, Decatur GA, Asheville NC,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT04142177

Recruiting
Active & Responsive

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for
Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation
Location: St Louis MO, Peoria IL, Iowa City IA, Indianapolis IN,
Sponsor: Chris Goss

Sex: All

Age: 6+

Code: NCT05548283

Recruiting
Active & Responsive

Gastroschisis Outcomes of Delivery (GOOD) Study

for
Gastroschisis
Location: St Louis MO, Peoria IL, Indianapolis IN, Kansas City MO,
Sponsor: Medical College of Wisconsin

Sex: Female

Age: 18+

Code: NCT02774746

Recruiting
Active & Responsive

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

for
Alagille Syndrome
Location: St Louis MO, Kansas City MO, Memphis TN, Dallas TX,
Sponsor: Ipsen

Sex: All

Age: 0+

Code: NCT06850038

Recruiting
Active & Responsive

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for
Alpha1-Antitrypsin Deficiency
Location: St Louis MO, Iowa City IA, Indianapolis IN,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT05677971

Phase 3, Recruiting
Active & Responsive

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for
NASH - Nonalcoholic Steatohepatitis,
Location: St Louis MO, Columbia MO, Clarksville TN,
Sponsor: Akero Therapeutics, Inc

Sex: All

Age: 18 - 70+

Code: NCT06528314

Phase 3, Recruiting
Active & ResponsiveNew

Using Personalized Rehabilitation to Reduce Disease and Increase Activity of Patients With Polymyalgia Rheumatica

for
Polymyalgia Rheumatica (PMR)
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 50+

Code: NCT07749547

Recruiting
Active & Responsive

Neuroimaging of Parkinson's

for
Parkinsons Disease (PD)
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 40+

Code: NCT07024875

Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Shiloh IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase 2, Phase 3, Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Shiloh IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase 2, Recruiting
Active & Responsive

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Shiloh IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06589804

Phase 3, Recruiting