Background illustration for clinical trials search

Paid Clinical Trials St. Louis

Discover 1,406 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

Filter
2
Active & Responsive

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for
Autoimmune Disease, Crohn Disease, Dermatomyositis,
Location: St Louis MO, Creve Coeur MO, City of Saint Peters MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03816345

Phase 1, Recruiting
Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: St Louis MO, Westwood KS, Indianapolis IN, Nashville TN,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase 3, Recruiting
Active & Responsive

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor, Adult, ERBB2 Altered Breast Cancer,
Location: St Louis MO, Nashville TN, Chicago IL, Grand Rapids MI,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07361562

Phase 1, Recruiting
Active & Responsive

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

for
Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL),
Location: St Louis MO, Chicago IL, Cincinnati OH, Omaha NE,
Sponsor: Umoja Biopharma

Sex: All

Age: 18+

Code: NCT06528301

Phase 1, Recruiting
Active & Responsive

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for
Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM,
Location: St Louis MO, Springdale AR, Madison WI, Omaha NE,
Sponsor: Black Diamond Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07326566

Phase 2, Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image
Active & Responsive

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

for
Multiple Myeloma, Relapsed/Refractory Multiple Myeloma
Location: St Louis MO, Iowa City IA, Indianapolis IN,
Sponsor: C4 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07284758

Phase 2, Recruiting
Active & Responsive

Study of DONQ52 in Active Celiac Disease

for
Celiac Disease
Location: St Louis MO, Columbia MO, Rockford IL, Hermitage TN,
Sponsor: Chugai Pharmaceutical

Sex: All

Age: 18 - 70+

Code: NCT07239336

Phase 2, Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

for
Moderate to Severe Chronic Obstructive Pulmonary Disease
Location: St Louis MO, Kansas City KS, Merrillville IN,
Sponsor: Pfizer

Sex: All

Age: 35 - 70+

Code: NCT07363694

Phase 2, Phase 3, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: St Louis MO, Kansas City MO, Chicago IL, Edgewood KY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase 3, Recruiting
Active & Responsive

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Location: St Louis MO, O'Fallon IL, Springfield IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07198074

Phase 3, Recruiting
Active & Responsive

Miro3D Randomized Controlled Trial (RCT)

for
Wound
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18 - 70+

Code: NCT07347106

Recruiting
Active & Responsive

Efficacy and Safety of a Ketogenic Diet in Type 1 Diabetes

for
Diabetes Mellitus, Type 1
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18 - 65

Code: NCT06503809

Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Centralia IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase 3, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for
Crohn's Disease
Location: St Louis MO, Indianapolis IN, Liberty MO,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 16 - 70+

Code: NCT06430801

Phase 3, Recruiting
Active & Responsive

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

for
Type 1 Diabetes Mellitus, T1D, T1DM,
Location: St Louis MO, Springfield IL, Indianapolis IN,
Sponsor: COUR Pharmaceutical Development Company, Inc.

Sex: All

Age: 12 - 35

Code: NCT06783309

Phase 1, Phase 2, Recruiting
Active & Responsive

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Location: St Louis MO, Indianapolis IN, Louisville KY,
Sponsor: Cleerly, Inc.

Sex: All

Age: 55+

Code: NCT06112418

Recruiting
Active & Responsive

Study to Understand Novel Biomarkers in Researching Dementia

for
Alzheimer Disease, Mild Cognitive Impairment, Dementia
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 60+

Code: NCT06547099

Recruiting
Active & Responsive

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for
Platinum-resistant Ovarian Cancer,
Location: St Louis MO, Indianapolis IN, Kettering OH,
Sponsor: Genelux Corporation

Sex: Female

Age: 18+

Code: NCT05281471

Phase 3, Recruiting
Active & Responsive

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for
PIK3CA Mutation, Solid Tumor, Adult,
Location: St Louis MO, Indianapolis IN, Nashville TN, Chicago IL,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05216432

Phase 1, Recruiting
Active & Responsive

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for
Surgery-Complications, Anesthesia Complication,
Location: St Louis MO, Little Rock AR, Ann Arbor MI, Detroit MI,
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05991453

Recruiting