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Paid Clinical Trials St. Louis

Discover 1,378 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: St Louis MO, Westwood KS, Indianapolis IN, Nashville TN,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase3, Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

for
Moderate to Severe Chronic Obstructive Pulmonary Disease
Location: St Louis MO, Merrillville IN, Hammond IN,
Sponsor: Pfizer

Sex: All

Age: 35 - 70+

Code: NCT07363694

Phase2, Phase3, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: St Louis MO, Kansas City MO, Chicago IL, Edgewood KY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase3, Recruiting
Active & Responsive

Miro3D Randomized Controlled Trial (RCT)

for
Wound
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18 - 70+

Code: NCT07347106

Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Centralia IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase3, Recruiting

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Active & Responsive

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for
Crohn's Disease
Location: St Louis MO, Indianapolis IN, Liberty MO,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 16 - 70+

Code: NCT06430801

Phase3, Recruiting
Active & Responsive

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Location: St Louis MO, Indianapolis IN, Louisville KY,
Sponsor: Cleerly, Inc.

Sex: All

Age: 55+

Code: NCT06112418

Recruiting
Active & Responsive

Study to Understand Novel Biomarkers in Researching Dementia

for
Alzheimer Disease, Mild Cognitive Impairment, Dementia
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 60+

Code: NCT06547099

Recruiting
Active & Responsive

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for
Platinum-resistant Ovarian Cancer,
Location: St Louis MO, Indianapolis IN, Kettering OH,
Sponsor: Genelux Corporation

Sex: Female

Age: 18+

Code: NCT05281471

Phase3, Recruiting
Active & Responsive

Mechanism of Ketogenic Diet-Induced Hypercholesterolemia

for
Hypercholesterolemia and Hyperlipidemia
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18 - 39

Code: NCT06894004

Recruiting
Active & Responsive

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for
Surgery-Complications, Anesthesia Complication,
Location: St Louis MO, Little Rock AR, Ann Arbor MI, Detroit MI,
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05991453

Recruiting
Active & Responsive

ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

for
Autosomal Dominant Polycystic Kidney Disease
Location: St Louis MO, Iowa City IA, Kansas City KS, Chicago IL,
Sponsor: Calico Life Sciences LLC

Sex: All

Age: 18 - 55

Code: NCT06902558

Phase2, Recruiting
Active & Responsive

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for
PIK3CA Mutation, Solid Tumor, Adult,
Location: St Louis MO, Indianapolis IN, Nashville TN, Chicago IL,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05216432

Phase1, Recruiting
Active & Responsive

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for
Treatment Resistant Depression
Location: St Louis MO, O'Fallon MO, Springfield IL, Columbia MO,
Sponsor: LivaNova

Sex: All

Age: 18+

Code: NCT03887715

Recruiting
Active & Responsive

64Cu-LLP2A for Imaging Hematologic Malignancies

for
Multiple Myeloma, Low-Grade Lymphoma, Follicular Lymphoma,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06636175

Early_phase1, Recruiting
Active & Responsive

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for
Treatment Resistant Depression
Location: St Louis MO, Indianapolis IN, Chicago IL, Milwaukee WI,
Sponsor: Abbott Medical Devices

Sex: All

Age: 22 - 70

Code: NCT06423430

Recruiting
Active & Responsive

FOG-001 in Locally Advanced or Metastatic Solid Tumors

for
Cancer, Colorectal Cancer, Solid Tumor,
Location: St Louis MO, Nashville TN, Madison WI, Rochester MN,
Sponsor: Parabilis Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05919264

Phase1, Phase2, Recruiting
Active & Responsive

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

for
Familial Hypercholesterolemia - Homozygous
Location: St Louis MO, Washington D.C. DC, Salt Lake City UT,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 2 - 11

Code: NCT06597006

Phase3, Recruiting
Active & Responsive

Evaluation of CCR2 in Patients Post Myocardial Infarction

for
Heart Diseases
Location: Saint Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 21 - 70+

Code: NCT05107596

Phase1, Recruiting
Active & Responsive

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: St Louis MO, Iowa City IA, Indianapolis IN,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 21

Code: NCT05183035

Phase3, Recruiting