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Paid Clinical Trials St. Louis

Discover 1,406 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

BioPoly® Partial Resurfacing Knee Implant IDE

for
Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage,
Location: Chesterfield MO, Indianapolis IN, Fort Wayne IN,
Sponsor: BioPoly LLC

Sex: All

Age: 30 - 65

Code: NCT06915363

Recruiting
Active & Responsive

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

for
Degenerative Disc Disease
Location: St Louis MO, Carmel IN, Louisville KY, Memphis TN,
Sponsor: DiscGenics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07254806

Phase 3, Recruiting
Active & Responsive

Impact of Weizmannia (Bacillus) Coagulans JBI-YZ6.3 on Gut Health and Fecal Microbiome Changes

for
Gastrointestinal Symptoms, Constipation, Gut Health,
Location: Saint Charles MO
Sponsor: Lindenwood University

Sex: All

Age: 18 - 50

Code: NCT07388264

Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the Prevention of Chronic Migraine

for
Preventive Treatment of Migraine
Location: City of Saint Peters MO, Indianapolis IN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07729462

Phase 3, Recruiting
Active & Responsive

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

for
Overweight, Obesity
Location: City of Saint Peters MO, Springfield MO, Louisville KY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07589608

Phase 2, Recruiting

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Active & Responsive

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain

for
Diabetic Peripheral Neuropathic Pain
Location: City of Saint Peters MO, Springfield MO, Chicago IL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07285018

Phase 2, Recruiting
Active & Responsive

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

for
Osteoarthritis, Knee, Diabetic Neuropathic Pain,
Location: City of Saint Peters MO, Springfield MO, Chicago IL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT05986292

Phase 2, Recruiting
Active & Responsive

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

for
Obesity, Overweight
Location: City of Saint Peters MO, Springfield MO, Louisville KY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT06143956

Phase 2, Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

for
Major Depressive Disorder (MDD)
Location: Saint Charles MO, Carmel IN, Chicago IL, Little Rock AR,
Sponsor: Vanda Pharmaceuticals

Sex: All

Age: 18 - 65

Code: NCT06830044

Phase 3, Recruiting
Active & Responsive

A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy

for
Kidney Disease
Location: City of Saint Peters MO, Kansas City MO, Rockford IL,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06963827

Phase 3, Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Saint Charles MO, Lincoln NE, Flowood MS,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase 2, Recruiting
Active & Responsive

RE104 Safety and Efficacy Study in Generalized Anxiety Disorder

for
Generalized Anxiety Disorder
Location: Saint Charles MO, Chicago IL, Little Rock AR,
Sponsor: Reunion Neuroscience Inc

Sex: All

Age: 18 - 70+

Code: NCT07489651

Phase 2, Recruiting
Active & Responsive

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

for
Treatment Resistant Depression
Location: Saint Charles MO, Chicago IL, Rogers AR, Little Rock AR,
Sponsor: atai Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT06524830

Phase 2, Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

for
Menstrual Migraine
Location: Weldon Spring MO, Evansville IN, Springfield MO,
Sponsor: Pfizer

Sex: Female

Age: 18 - 45

Code: NCT06641466

Phase 3, Recruiting
Active & Responsive

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for
Major Depressive Disorder
Location: Saint Charles MO, O'Fallon MO, Little Rock AR,
Sponsor: Neurocrine Biosciences

Sex: All

Age: 18+

Code: NCT06966401

Phase 3, Recruiting

Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

for
Prurigo Nodularis
Location: St Louis MO, Lee's Summit MO, Indianapolis IN,
Sponsor: Galderma R&D

Sex: All

Age: 18+

Code: NCT06988618

Recruiting

A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer

for
Solid Tumor, Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: St Louis MO, Durham NC, Houston TX, Aurora CO,
Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female

Age: 18+

Code: NCT04516447

Phase 1, Recruiting

A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)

for
Narcolepsy Type 2
Location: St Louis MO, Cincinnati OH, Lansing MI,
Sponsor: Takeda

Sex: All

Age: 18 - 70

Code: NCT06952699

Phase 2, Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: O'Fallon IL, Shiloh IL, Springfield IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06058377

Phase 3, Recruiting

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for
Fallopian Tube Endometrioid Adenocarcinoma,
Location: Saint Louis MO, Sunset Hills MO, O'Fallon IL, Alton IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06580314

Phase 3, Recruiting