Discover 1,406 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
St. Louis currently offers medical research opportunities for a variety of conditions, including cancer, heart disease, prurigo nodularis, and pain management. The city's leading institutions are actively recruiting participants, offering opportunities for healthy volunteers in paid studies, as well as those seeking trials for specific health conditions, providing access to innovative treatments and advanced medical care.
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Results: 1,406
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for
Anatomic Stage I Breast Cancer AJCC v8,
Location: St Louis MO, Sunset Hills MO, Creve Coeur MO,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 18+
Code: NCT06876714
Phase 3, Recruiting
A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)
for
Extensive Stage Small Cell Lung Cancer
Location: St Louis MO, Memphis TN, Louisville KY, Atlanta GA,
Sponsor: Amgen
Sex: All
Age: 18 - 70+
Code: NCT07037758
Phase 1, Recruiting
Clinical Study of MK-4884 in Participants With Advanced or Metastatic Solid Tumors (MK-4884-001)
for
Malignant Neoplasm
Location: St Louis MO, Toronto, San Antonio TX, Montreal
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT07600749
Phase 1, Recruiting
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
for
Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Shiloh IL,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 65+
Code: NCT07321652
Phase 3, Recruiting
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)
for
Core Binding Factor Acute Myeloid Leukemia
Location: St Louis MO, Creve Coeur MO, City of Saint Peters MO,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18 - 59
Code: NCT06917911
Phase 2, Recruiting
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Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
for
Urothelial Cancer, Urinary Bladder Neoplasms
Location: St Louis MO, Columbia MO, New Lenox IL, Hinsdale IL,
Sponsor: Astellas Pharma Global Development, Inc.
Sex: All
Age: 18+
Code: NCT07566156
Phase 3, Recruiting
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
for
KRAS Altered Advanced or Metastatic Solid Tumors
Location: St Louis MO, Nashville TN, Atlanta GA, Durham NC,
Sponsor: Amgen
Sex: All
Age: 18+
Code: NCT07094113
Phase 1, Recruiting
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
for
Carcinoma, Hepatocellular, Hepatocellular Cancer,
Location: St Louis MO, Florissant MO, Creve Coeur MO, Shiloh IL,
Sponsor: Pfizer
Sex: All
Age: 18+
Code: NCT07227012
Phase 1, Phase 2, Recruiting
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
for
Prostate Cancer (Adenocarcinoma)
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: Canadian Cancer Trials Group
Sex: Male
Age: 18+
Code: NCT06592924
Phase 3, Recruiting
A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab
Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma
for
High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements,
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT06649812
Phase 2, Recruiting
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
for
Breast Neoplasms, Triple Negative Breast Neoplasms,
Location: St Louis MO, Carterville IL, Indianapolis IN,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT06966700
Phase 3, Recruiting
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
for
Pancreatic Neuroendocrine Tumor (pNET),
Location: St Louis MO, Nashville TN, Lexington KY, Milwaukee WI,
Sponsor: Exelixis
Sex: All
Age: 18+
Code: NCT06943755
Phase 2, Phase 3, Recruiting
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
Location: St Louis MO, Florissant MO, Creve Coeur MO, Shiloh IL,
Sponsor: Pfizer
Sex: All
Age: 18+
Code: NCT07227415
Phase 1, Phase 2, Recruiting
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
for
Metastatic Head-and-neck Squamous-cell Carcinoma,
Location: St Louis MO, Westwood KS, Chicago IL, Columbus OH,
Sponsor: AVEO Pharmaceuticals, Inc.
Sex: All
Age: 18+
Code: NCT06064877
Phase 3, Recruiting
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
for
Castration-Resistant Prostate Carcinoma,
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Shiloh IL,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 18+
Code: NCT06632977
Phase 2, Recruiting
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for
Advanced Malignant Solid Neoplasm,
Location: St Louis MO, Sunset Hills MO, Creve Coeur MO,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 0+
Code: NCT05564377
Phase 2, Recruiting
Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers
for
Metastatic Salivary Gland Carcinoma,
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: NRG Oncology
Sex: All
Age: 18+
Code: NCT05408845
Phase 2, Recruiting
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
for
Acute Myeloid Leukemia,
Location: St Louis MO, Creve Coeur MO, O'Fallon IL,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18 - 59
Code: NCT05554406
Phase 2, Recruiting
Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment