Discover 1,378 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
St. Louis currently offers medical research opportunities for a variety of conditions, including cancer, heart disease, prurigo nodularis, and pain management. The city's leading institutions are actively recruiting participants, offering opportunities for healthy volunteers in paid studies, as well as those seeking trials for specific health conditions, providing access to innovative treatments and advanced medical care.
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Results: 1,378
Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia
for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative,
Location: St Louis MO, Creve Coeur MO, City of Saint Peters MO,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT03739814
Phase2, Recruiting
Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity
for
Gastric Adenocarcinoma,
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All
Age: 18+
Code: NCT07001748
Phase2, Phase3, Recruiting
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
for
Advanced Hepatocellular Carcinoma,
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: NRG Oncology
Sex: All
Age: 18+
Code: NCT07166406
Phase3, Recruiting
Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer
for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT07195734
Phase2, Recruiting
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
for
Untreated, Unresectable, or Metastatic Colorectal Cancer
Location: St Louis MO, Nashville TN, Springdale AR, Omaha NE,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18+
Code: NCT07221357
Phase2, Phase3, Recruiting
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Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer
for
Non-small Cell Lung Cancer
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Shiloh IL,
Sponsor: Canadian Cancer Trials Group
Sex: All
Age: 18+
Code: NCT06686771
Phase3, Recruiting
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
for
Locally Advanced Urothelial Carcinoma,
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Shiloh IL,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT06524544
Phase3, Recruiting
Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer
for
Locally Advanced Adrenal Cortical Carcinoma,
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 12+
Code: NCT06900595
Phase2, Recruiting
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for
Anatomic Stage I Breast Cancer AJCC v8,
Location: St Louis MO, Sunset Hills MO, Creve Coeur MO,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 18+
Code: NCT06876714
Phase3, Recruiting
A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)
for
Extensive Stage Small Cell Lung Cancer
Location: St Louis MO, Memphis TN, Louisville KY, Atlanta GA,
Sponsor: Amgen
Sex: All
Age: 18 - 70+
Code: NCT07037758
Phase1, Recruiting
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
for
Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia
Location: St Louis MO, Creve Coeur MO, O'Fallon IL, Shiloh IL,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 65+
Code: NCT07321652
Phase3, Recruiting
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)
for
Core Binding Factor Acute Myeloid Leukemia
Location: St Louis MO, Creve Coeur MO, City of Saint Peters MO,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18 - 59
Code: NCT06917911
Phase2, Recruiting
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
for
KRAS Altered Advanced or Metastatic Solid Tumors
Location: St Louis MO, Nashville TN, Atlanta GA, Durham NC,
Sponsor: Amgen
Sex: All
Age: 18+
Code: NCT07094113
Phase1, Recruiting
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
for
Carcinoma, Hepatocellular, Hepatocellular Cancer,
Location: St Louis MO, Florissant MO, Creve Coeur MO, Shiloh IL,
Sponsor: Pfizer
Sex: All
Age: 18+
Code: NCT07227012
Phase1, Phase2, Recruiting
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
for
Prostate Cancer (Adenocarcinoma)
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: Canadian Cancer Trials Group
Sex: Male
Age: 18+
Code: NCT06592924
Phase3, Recruiting
A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab
Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma
for
High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements,
Location: St Louis MO, Creve Coeur MO, Shiloh IL,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT06649812
Phase2, Recruiting
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
for
Breast Neoplasms, Triple Negative Breast Neoplasms,
Location: St Louis MO, Indianapolis IN, Kansas City MO,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT06966700
Phase3, Recruiting
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
for
Pancreatic Neuroendocrine Tumor (pNET),
Location: St Louis MO, Nashville TN, Lexington KY, Milwaukee WI,
Sponsor: Exelixis
Sex: All
Age: 18+
Code: NCT06943755
Phase2, Phase3, Recruiting
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
for
Metastatic Head-and-neck Squamous-cell Carcinoma,
Location: St Louis MO, Westwood KS, Chicago IL, Columbus OH,