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Paid Clinical Trials St. Louis

Discover 1,378 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

for
Bronchiectasis With Pseudomonas Aeruginosa Colonization
Location: St Louis MO, Kansas City KS, Ann Arbor MI, Rock Hill SC,
Sponsor: AstraZeneca

Sex: All

Age: 12+

Code: NCT07088926

Phase2, Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for
Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma,
Location: St Louis MO, Cleveland OH, Durham NC, Fairfax VA,
Sponsor: Plexium, Inc.

Sex: All

Age: 18+

Code: NCT07284186

Phase1, Recruiting

An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

for
Multiple Sclerosis
Location: St Louis MO, Milwaukee WI, Washington D.C. DC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 60

Code: NCT07224373

Phase1, Recruiting

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for
Gastric Cancer, Gastroesophageal Junction Adenocarcinoma,
Location: St Louis MO, Kansas City MO, Nashville TN, Niles IL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07431281

Phase3, Recruiting

A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine

for
Migraine
Location: St Louis MO, Hazelwood MO, City of Saint Peters MO,
Sponsor: Kallyope Inc.

Sex: All

Age: 18 - 70+

Code: NCT07645924

Phase3, Recruiting

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A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

for
Rheumatoid Arthritis
Location: St Louis MO, Willowbrook IL, Windsor, Lake Charles LA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07276581

Phase2, Recruiting

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors

for
ER+ HER2- Advanced Breast Cancer,
Location: St Louis MO, Nashville TN, Houston TX, Providence RI
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT06188520

Phase1, Phase2, Recruiting

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

for
Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer,
Location: St Louis MO, Pittsburgh PA, Charlotte NC, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05123482

Phase1, Phase2, Recruiting

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

for
Hepatocellular Carcinoma
Location: St Louis MO, Houston TX, Los Angeles CA
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06795022

Phase1, Phase2, Recruiting

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for
Proteinuric Kidney Disease
Location: St Louis MO, City of Saint Peters MO, Bowling Green KY,
Sponsor: Maze Therapeutics

Sex: All

Age: 18 - 68

Code: NCT06830629

Phase2, Recruiting

Study of AZD0754 in Participants With Metastatic Prostate Cancer

for
Metastatic Prostate Cancer
Location: St Louis MO, Atlanta GA, Houston TX, Philadelphia PA,
Sponsor: AstraZeneca

Sex: Male

Age: 18 - 70+

Code: NCT06267729

Phase1, Phase2, Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for
Non-Small Cell Lung Cancer
Location: St Louis MO, Carterville IL, Jonesboro AR,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT06767514

Phase3, Recruiting

A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

for
Plasma Cell Myeloma Refractory
Location: St Louis MO, Kansas City MO, Nashville TN,
Sponsor: Sanofi

Sex: All

Age: 18+

Code: NCT06356571

Phase2, Recruiting

Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)

for
Excessive Sleepiness, Shift-work Disorder
Location: St Louis MO, Chesterfield MO, Chicago IL,
Sponsor: Axsome Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT06568367

Phase3, Recruiting

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

for
Transthyretin Amyloidosis, ATTR-CM, ATTRv-PN, ATTR, ATTR-Mixed,
Location: St Louis MO, Indianapolis IN, Kansas City MO,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06465810

Recruiting

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

for
Solid Tumors
Location: St Louis MO, Nashville TN, Cleveland OH, Houston TX,
Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All

Age: 18+

Code: NCT06386146

Phase1, Phase2, Recruiting

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

for
Biliary Tract Cancer
Location: St Louis MO, Kansas City MO, Chicago IL, Niles IL,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06467357

Phase3, Recruiting

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Location: St Louis MO, Louisville KY, Nashville TN, Niles IL,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06129864

Phase3, Recruiting

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for
HER2-positive Gastric Cancer,
Location: St Louis MO, Louisville KY, Hinsdale IL, Chicago IL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06764875

Phase3, Recruiting

Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

for
Hereditary Angioedema (HAE)
Location: St Louis MO, Wheaton IL, Little Rock AR, Milwaukee WI,
Sponsor: Pharvaris Netherlands B.V.

Sex: All

Age: 12+

Code: NCT06679881

Phase3, Recruiting