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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for
Metastatic Uveal Melanoma
Location: Durham NC, Washington D.C. DC, Knoxville TN,
Sponsor: Replimune Inc.

Sex: All

Age: 0+

Code: NCT06581406

Phase2, Phase3, Recruiting

A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer

for
Prostate Cancer
Location: Durham NC, Basking Ridge NJ, Middletown NJ, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Male

Age: 18+

Code: NCT06457919

Phase1, Phase2, Recruiting

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

for
Prostate Cancer
Location: Durham NC, Roanoke VA, Washington D.C. DC, Athens GA,
Sponsor: Novartis Pharmaceuticals

Sex: Male

Age: 18 - 70+

Code: NCT05803941

Recruiting

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for
Myelodysplastic Syndrome
Location: Durham NC, Greenville NC, Richmond VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06577441

Phase2, Recruiting

Exercise and Soft Tissue Sarcoma

for
Soft Tissue Sarcoma
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 70+

Code: NCT04921917

Recruiting

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Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

for
Metastatic Prostate Cancer
Location: Durham NC, Myrtle Beach SC, Norfolk VA,
Sponsor: Janssen Research & Development, LLC

Sex: Male

Age: 18+

Code: NCT06800313

Phase1, Phase2, Recruiting

Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

for
Obstetrical Complications, Labor and Delivery Complication,
Location: Durham NC, Chapel Hill NC, Pittsburgh PA,
Sponsor: The George Washington University Biostatistics Center

Sex: Female

Age: 0+

Code: NCT06605118

Phase3, Recruiting

Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer

for
Stage I Uterine Corpus Endometrial Stromal Sarcoma AJCC v8,
Location: Durham NC, Chapel Hill NC, Raleigh NC, Richmond VA,
Sponsor: NRG Oncology

Sex: Female

Age: 18+

Code: NCT06388018

Phase2, Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

for
Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL,
Location: Durham NC, Newark DE, Columbus OH, Canton OH,
Sponsor: Schrödinger, Inc.

Sex: All

Age: 18+

Code: NCT05544019

Phase1, Recruiting

Deep Functional Phenotyping of the ALA Lung Health Cohort

for
Lung Diseases
Location: Durham NC, Winston-Salem NC, Baltimore MD,
Sponsor: Johns Hopkins University

Sex: All

Age: 25 - 35

Code: NCT06177717

Recruiting

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for
mCRPC (Metastatic Castration-resistant Prostate Cancer),
Location: Durham NC, Fairfax VA, Baltimore MD, Atlanta GA,
Sponsor: Pathos AI, Inc.

Sex: Male

Age: 18+

Code: NCT06785636

Phase1, Phase2, Recruiting

Cognitive and Neurological Pathologies in Pompe Disease

for
Pompe Disease
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 0 - 18

Code: NCT04639336

Recruiting

Pharmacokinetics of Drugs Administered to Children

for
Pediatric ALL
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 0 - 20

Code: NCT03481881

Recruiting

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

for
Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis,
Location: Durham NC, Richmond VA, Greenville SC, Falls Church VA,
Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All

Age: 18 - 70+

Code: NCT06563895

Phase3, Recruiting

Pilot Study for Speculum Free Cervical Cancer Screening

for
Cervical Cancer
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 21 - 65

Code: NCT04107181

Recruiting

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for
Lung Carcinoma
Location: Durham NC, Columbus OH, Newnan GA, New Haven CT,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06196008

Recruiting

Struvite Stones Antibiotic Study

for
Kidney Stones
Location: Durham NC, Baltimore MD, Athens OH, Cleveland OH,
Sponsor: University of British Columbia

Sex: All

Age: 19+

Code: NCT02375295

Recruiting

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for
Myelofibrosis, Post-PV MF, Post-ET Myelofibrosis,
Location: Durham NC, Wilson NC, Winston-Salem NC, Charlotte NC,
Sponsor: Kartos Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06479135

Phase3, Recruiting

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for
AL Amyloidosis
Location: Durham NC, Winston-Salem NC, Mooresville NC,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06022939

Phase3, Recruiting

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for
Heart Diseases, Coronary Artery Disease,
Location: Durham NC, Winston-Salem NC, Greenville NC,
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18+

Code: NCT04124120

Recruiting