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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

for
Clear Cell Renal Cell Carcinoma
Location: Durham NC, Charlotte NC, Atlanta GA, Columbus OH,
Sponsor: Xencor, Inc.

Sex: All

Age: 18+

Code: NCT05433142

Phase1, Recruiting

Caphosol for the Reduction of Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

for
Oral Mucositis
Location: Durham NC, Philadelphia PA, New York NY, Gainesville FL,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT00901732

Phase1, Phase2, Recruiting

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

for
Colorectal Anastomosis, Left-sided Colon Resection,
Location: Durham NC, Wynnewood PA, Columbus OH, New Haven CT,
Sponsor: Medtronic - MITG

Sex: All

Age: 18+

Code: NCT07351071

Recruiting

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

for
Advanced Solid Tumor Cancer
Location: Durham NC, Baltimore MD, Pittsburgh PA, Philadelphia PA,
Sponsor: Calico Life Sciences LLC

Sex: All

Age: 18+

Code: NCT04777994

Phase1, Recruiting

Phase I/II Trial of Doxil and Hyperthermia for Breast Cancer Patients With Chest Wall Recurrence or Stage IV Disease With Locally Advanced Breast Cancer

for
Breast Cancer
Location: Durham NC
Sponsor: National Center for Research Resources (NCRR)

Sex: Female

Age: 18 - 70+

Code: NCT00006433

Phase2, Recruiting

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A Study of YL201 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Chapel Hill NC, Fairfax VA, Washington D.C. DC,
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All

Age: 18+

Code: NCT05434234

Phase1, Phase2, Recruiting

Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration

for
Neovascular (Wet) Age-Related Macular Degeneration
Location: Wake Forest NC, Erie PA, The Woodlands TX, Bellaire TX,
Sponsor: Eyconis INC.

Sex: All

Age: 50+

Code: NCT07587515

Phase1, Phase2, Recruiting
Active & Responsive

Oxygen Toxicity: Mechanisms in Humans

for
Oxygen Toxicity, Hypercapnia, Seizures
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 45

Code: NCT05761756

Recruiting
Featured

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

for
Crohn's Disease
Location: Chapel Hill NC, Philadelphia PA, Cleveland OH,
Sponsor: AbbVie

Sex: All

Age: 2 - 17

Code: NCT06332534

Phase3, Recruiting
Featured

A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

for
Multiple Myeloma
Location: Chapel Hill NC, Roanoke VA, Fairfax VA, Atlanta GA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07095452

Phase2, Phase3, Recruiting
Featured

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia (CLL)
Location: Chapel Hill NC, Winston-Salem NC, Charlotte NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT04895436

Phase2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan

for
Solid Tumors Harboring MET Amplification
Location: Durham NC, Fairfax VA, New York NY, Nashville TN,
Sponsor: AbbVie

Sex: All

Age: 12+

Code: NCT07196644

Phase2, Recruiting
Featured

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for
Non-Small Cell Lung Cancer,
Location: Durham NC, Huntersville NC, Fairfax VA, Louisville KY,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT05005403

Phase1, Recruiting

Effect of Mobilization in Conjunction With Exercise in Participants With a History of Chronic Ankle Instability

for
Ankle Sprains
Location: Fayetteville NC, Winchester VA
Sponsor: Shenandoah University

Sex: All

Age: 18 - 35

Code: NCT03428620

Recruiting

A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

for
Heterozygous Familial Hypercholesterolemia,
Location: High Point NC, Philadelphia PA, Jacksonville FL,
Sponsor: Verve Therapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT06164730

Phase1, Recruiting

Pre- and Post-neuromusculoskeletal Injury Risk Evaluation for Return-to-Duty Enhancement

for
Musculoskeletal Injuries
Location: Fort Liberty NC, Bethesda MD
Sponsor: Womack Army Medical Center

Sex: All

Age: 18 - 44

Code: NCT05111925

Recruiting

Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI

for
Posttraumatic Headache, Mild Traumatic Brain Injury
Location: Fort Bragg NC, El Paso TX
Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine

Sex: All

Age: 18 - 50

Code: NCT05049057

Phase2, Recruiting

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

for
Concussion, Brain
Location: Fort Liberty NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 70+

Code: NCT05320822

Recruiting

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

for
Traumatic Brain Injury, Insomnia, Depression,
Location: Fort Bragg NC, Bethesda MD, Eglin Air Force Base FL,
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT05663034

Recruiting

Nutrition for Post-Traumatic Headache

for
Post-Traumatic Headache Chronic Without Intractable Headache
Location: Fort Bragg NC, Fort Belvoir VA, Bethesda MD
Sponsor: Uniformed Services University of the Health Sciences

Sex: All

Age: 18+

Code: NCT03272399

Phase2, Recruiting