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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Emovi 3D Knee Assessment Device Intervention for Operational Readiness

for
Patellofemoral Pain, Patellofemoral Pain Syndrome
Location: Fort Liberty NC
Sponsor: Womack Army Medical Center

Sex: All

Age: 18 - 50

Code: NCT06517056

Recruiting

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

for
Breast Cancer
Location: Rocky Mount NC, Pinehurst NC, Winston-Salem NC,
Sponsor: Exact Sciences Corporation

Sex: All

Age: 18+

Code: NCT06401421

Recruiting

Vitamin D for Prostate Endocrine Therapy

for
Stage I Prostate Cancer AJCC v8,
Location: Rocky Mount NC, Roanoke VA, New Bern NC, Midlothian VA,
Sponsor: University of Rochester

Sex: Male

Age: 50+

Code: NCT05838716

Phase3, Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Wilson NC, Fredericksburg VA, Fairfax VA, Bethesda MD,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06692738

Phase3, Recruiting

Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Wilson NC, Pinehurst NC, Atlanta GA, Canton OH,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06899126

Phase3, Recruiting

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A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

for
Squamous Cell Carcinoma of Head and Neck
Location: Wilson NC, Charlottesville VA, Fairfax VA, Baltimore MD,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07276399

Phase3, Recruiting

BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

for
HR+/HER2- Breast Cancer
Location: Wilson NC, Blacksburg VA, Richmond VA, Kingsport TN,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07492641

Phase3, Recruiting

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Wilson NC, Winston-Salem NC, Charlotte NC, Fairfax VA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06667076

Phase2, Recruiting

ELEVATE-HFpEF Clinical Study

for
Heart Failure With Preserved Ejection Fraction (HFpEF)
Location: Durham NC, Falls Church VA, Charleston WV,
Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All

Age: 40+

Code: NCT06678841

Recruiting

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

for
Limited Stage Small Cell Lung Cancer
Location: Wilson NC, Salem VA, Norfolk VA, Fairfax VA,
Sponsor: SCRI Development Innovations, LLC

Sex: All

Age: 18+

Code: NCT06773910

Phase2, Recruiting

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic Solid Tumor
Location: Wilson NC, Fairfax VA, Atlanta GA, East Brunswick NJ,
Sponsor: Pliant Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06270706

Phase1, Recruiting

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for
Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer,
Location: Wilson NC, Pinehurst NC, Charlottesville VA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07222566

Phase3, Recruiting

Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

for
Severe Hypertriglyceridemia
Location: Greensboro NC, Wilmington NC, Pittsburgh PA,
Sponsor: Arrowhead Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06880770

Phase3, Recruiting

ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome

for
Dravet Syndrome
Location: Durham NC, Ann Arbor MI, Memphis TN, Montreal,
Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All

Age: 2 - 12

Code: NCT07531745

Phase1, Phase2, Recruiting

A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

for
Uncontrolled Gout
Location: Greensboro NC, Salisbury NC, Shelby NC, Charlotte NC,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT07388498

Phase3, Recruiting

Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

for
Obesity, Overweight
Location: Danville VA, Morehead City NC, Mauldin SC, Columbia MD,
Sponsor: Kailera

Sex: All

Age: 18+

Code: NCT07284875

Phase3, Recruiting

Utility of PharmacoGenomics for Reducing Adverse Drug Effects

for
Genetics of Drug Metabolism
Location: Asheboro NC, South Chesterfield VA, Asheville NC,
Sponsor: Companion Dx Reference Lab, LLC

Sex: All

Age: 18+

Code: NCT02081872

Recruiting

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

for
Uncontrolled Hypertension
Location: Asheboro NC, Monroe NC, Charlotte NC, Vienna VA,
Sponsor: Retension Pharmaceuticals. Inc.

Sex: All

Age: 18 - 70

Code: NCT07142356

Phase2, Recruiting

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for
Lymphoma, Malignant Solid Neoplasm
Location: Greensboro NC, Kernersville NC, Thomasville NC,
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT05006482

Phase3, Recruiting

Tesetaxel as First-line Therapy for Metastatic Breast Cancer

for
Breast Neoplasm
Location: Greensboro NC, New York NY, Dallas TX
Sponsor: Genta Incorporated

Sex: Female

Age: 18+

Code: NCT01221870

Phase2, Recruiting