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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

for
Overweight, Obesity
Location: Chapel Hill NC, Greensboro NC, Wilmington NC,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07392190

Phase3, Recruiting

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

for
Crohn Disease
Location: Chapel Hill NC, Suwanee GA, Crestview Hills KY,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07577843

Phase3, Recruiting

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

for
Acute Myeloid Leukemia With FLT3/ITD Mutation,
Location: Chapel Hill NC, Philadelphia PA, Columbus OH,
Sponsor: Uma Borate

Sex: All

Age: 18+

Code: NCT06222580

Phase1, Recruiting

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

for
Unresectable Melanoma, Metastatic Melanoma, Ocular Melanoma
Location: Chapel Hill NC, Nashville TN, Denver CO
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT06940739

Phase1, Phase2, Recruiting

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Chapel Hill NC, Norfolk VA, Philadelphia PA, Atlanta GA,
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06297226

Phase2, Recruiting

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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for
Solid Tumor
Location: Chapel Hill NC, Pittsburgh PA, Jacksonville FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT04939610

Phase1, Phase2, Recruiting

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for
Melanoma, Cutaneous Malignant
Location: Chapel Hill NC, Richmond VA, Baltimore MD,
Sponsor: Immatics US, Inc.

Sex: All

Age: 18+

Code: NCT06743126

Phase3, Recruiting

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

for
Surgery, Pain, Postoperative
Location: Chapel Hill NC, Camden NJ, Philadelphia PA, Detroit MI,
Sponsor: University of Michigan

Sex: All

Age: 18+

Code: NCT05722002

Recruiting

Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer (NSCLC)
Location: Chapel Hill NC, Fairfax VA, Washington D.C. DC,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT07288177

Phase2, Recruiting

Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma

for
Pancreatic Ductal Adenocarcinoma
Location: Chapel Hill NC, Philadelphia PA, New York NY,
Sponsor: Gulam Manji

Sex: All

Age: 18+

Code: NCT06048484

Phase2, Recruiting

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

for
Hormone Receptor Positive HER-2 Negative Breast Cancer,
Location: Chapel Hill NC, Richmond VA, Pittsburgh PA,
Sponsor: Puma Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT06369285

Phase2, Recruiting
New

Evaluation of the Melanin-Adjusted Blood Oxygen Sensor (MABOS) in ICU Settings

for
Hypoxemia
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 70+

Code: NCT07799454

Recruiting

Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

for
Acute Ischemic Stroke
Location: Raleigh NC, Camden NJ, Columbus OH, Toledo OH,
Sponsor: Basking Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT06226805

Phase2, Recruiting

Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

for
Ig-E Mediated Food Allergy
Location: Chapel Hill NC, Washington D.C. DC, Pittsburgh PA,
Sponsor: RAPT Therapeutics, Inc.

Sex: All

Age: 12 - 55

Code: NCT07220811

Phase2, Recruiting

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

for
Urothelial Cancer, Bladder Cancer
Location: Chapel Hill NC, Norfolk VA, Nashville TN,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT07129993

Phase2, Phase3, Recruiting

AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

for
Epithelial Ovarian Cancer
Location: Chapel Hill NC, Roanoke VA, Fairfax VA,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT07218809

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

for
Asthma
Location: Chapel Hill NC, Baltimore MD, Northfield NJ, Atlanta GA,
Sponsor: AstraZeneca

Sex: All

Age: 5 - 11

Code: NCT06023589

Phase3, Recruiting

Angelman Syndrome Natural History Study

for
Angelman Syndrome
Location: Carrboro NC, Atlanta GA, Nashville TN, Boston MA,
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT04507997

Recruiting

TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

for
Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy,
Location: Chapel Hill NC, Baltimore MD, New York NY, Nashville TN,
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07223203

Phase3, Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

for
SLE (Systemic Lupus), Lupus Erythematosus, Systemic,
Location: Chapel Hill NC, Boston MA, Chicago IL, St Louis MO,
Sponsor: CRISPR Therapeutics

Sex: All

Age: 18 - 70

Code: NCT06925542

Phase1, Recruiting